PMID- 29623218
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220316
IS  - 2058-4601 (Print)
IS  - 2058-4601 (Electronic)
VI  - 7
IP  - 3
DP  - 2018 Mar
TI  - The influence of a peritoneovenous shunt for cirrhotic and malignant intractable 
      ascites on renal function.
PG  - 2058460118764208
LID - 10.1177/2058460118764208 [doi]
LID - 2058460118764208
AB  - BACKGROUND: Peritoneovenous shunts (PVS) are widely used for palliation of 
      intractable ascites caused by peritoneal carcinomatosis (PC) or liver cirrhosis 
      (LC). Some patients who need PVS have renal dysfunction. However, renal 
      dysfunction is considered a relative contraindication. Therefore, it is important 
      to assess renal function before PVS placement. PURPOSE: To evaluate the 
      relationship between PVS and renal function. MATERIAL AND METHODS: Between 
      October 2007 and July 2015, 60 patients (PC = 47; LC = 10; others = 3) underwent 
      PVS placement for intractable ascites. Changes in estimated glomerular filtration 
      rate (eGFR) and other adverse events (AEs) were retrospectively analyzed. 
      RESULTS: Changes in eGFR before, one day after, and one week after PVS placement 
      could be evaluated in 46 patients. The median eGFR before, one day after, and one 
      week after was 56.5, 59.1, and 64.7 mL/min/1.73 m(2), respectively (P < 0.05). 
      These values were 61.6, 72, and 67.1 mL/min/1.73 m(2), respectively, in PC 
      patients (n = 34; P < 0.05) and 28.5, 27, and 37.2 mL/min/1.73 m(2), 
      respectively, in LC patients (n = 10; P < 0.05). In 17 patients with moderate to 
      severe renal dysfunction (eGFR < 45), these values were 23.4, 23.7, and 
      30.5 mL/min/1.73 m(2), respectively. The most frequent AE was PVS catheter 
      obstruction, which occurred in 12 patients (20.7%). Clinical disseminated 
      intravascular coagulation occurred in six patients (10.3%) and caused death in 
      three patients (5.2%). CONCLUSION: PVS placement for intractable ascites is 
      associated with various AEs. However, PVS appeared to promote renal function, 
      especially in patients with renal impairment.
FAU - Segawa, Takafumi
AU  - Segawa T
AD  - Department of Radiology, Iwate Medical University, Morioka, Japan.
FAU - Kato, Kenichi
AU  - Kato K
AD  - Department of Radiology, Iwate Medical University, Morioka, Japan.
FAU - Kawashima, Kazuya
AU  - Kawashima K
AD  - Department of Radiology, Iwate Medical University, Morioka, Japan.
FAU - Suzuki, Tomohiro
AU  - Suzuki T
AD  - Department of Radiology, Iwate Medical University, Morioka, Japan.
FAU - Ehara, Shigeru
AU  - Ehara S
AD  - Department of Radiology, Iwate Medical University, Morioka, Japan.
LA  - eng
PT  - Journal Article
DEP - 20180326
PL  - England
TA  - Acta Radiol Open
JT  - Acta radiologica open
JID - 101651010
PMC - PMC5881988
OTO - NOTNLM
OT  - Peritoneovenous shunt
OT  - ascites
OT  - liver cirrhosis
OT  - peritoneal carcinomatosis
EDAT- 2018/04/07 06:00
MHDA- 2018/04/07 06:01
PMCR- 2018/03/26
CRDT- 2018/04/07 06:00
PHST- 2017/07/21 00:00 [received]
PHST- 2018/02/10 00:00 [accepted]
PHST- 2018/04/07 06:00 [entrez]
PHST- 2018/04/07 06:00 [pubmed]
PHST- 2018/04/07 06:01 [medline]
PHST- 2018/03/26 00:00 [pmc-release]
AID - 10.1177_2058460118764208 [pii]
AID - 10.1177/2058460118764208 [doi]
PST - epublish
SO  - Acta Radiol Open. 2018 Mar 26;7(3):2058460118764208. doi: 
      10.1177/2058460118764208. eCollection 2018 Mar.