PMID- 29624126
OWN - NLM
STAT- MEDLINE
DCOM- 20190715
LR  - 20230928
IS  - 1552-8456 (Electronic)
IS  - 0193-9459 (Print)
IS  - 0193-9459 (Linking)
VI  - 41
IP  - 4
DP  - 2019 Apr
TI  - Health-Related Quality of Life and Personal Life Goals of Adults With Sickle Cell 
      Disease After Hematopoietic Stem Cell Transplantation.
PG  - 555-575
LID - 10.1177/0193945918768277 [doi]
AB  - Allogeneic hematopoietic stem cell transplantation (HSCT) from a human leukocyte 
      antigen (HLA)-matched sibling donor offers a unique therapy to reverse SCD. This 
      mixed-methods study explores recipients' perception of HSCT success, personal 
      life goals, and associated health-related quality of life (HRQOL) more than 1 
      year after HSCT. Recipients completed the Short Form-36, version 1 (SF-36v1) 
      HRQOL survey followed by a 60- to 90-min face-to-face or telephone audio-recorded 
      interview. Eleven of 15 eligible recipients participated in the study. Although 
      the eight HRQOL subscale scores varied, the three recipients with a successful 
      HSCT and the highest scores were pursuing their personal life goals. The four 
      with avascular necrosis (AVN) had lower scores related to AVN limitations, yet 
      they were pursuing their personal goals. The two reporting a failed HSCT had 
      reverted back to having SCD, and their subscale scores were among the lowest. Our 
      results show that HSCT success, ability to pursue goals, and HRQOL align in 
      predictable ways.
FAU - Gallo, Agatha M
AU  - Gallo AM
AUID- ORCID: 0000-0002-4419-8210
AD  - 1 University of Illinois at Chicago, IL, USA.
FAU - Patil, Crystal
AU  - Patil C
AD  - 1 University of Illinois at Chicago, IL, USA.
FAU - Adeniyi, Tokunbo
AU  - Adeniyi T
AD  - 1 University of Illinois at Chicago, IL, USA.
FAU - Hsu, Lewis L
AU  - Hsu LL
AD  - 1 University of Illinois at Chicago, IL, USA.
FAU - Rondelli, Damiano
AU  - Rondelli D
AD  - 1 University of Illinois at Chicago, IL, USA.
FAU - Saraf, Santosh
AU  - Saraf S
AD  - 1 University of Illinois at Chicago, IL, USA.
LA  - eng
GR  - K23 HL125984/HL/NHLBI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20180406
PL  - United States
TA  - West J Nurs Res
JT  - Western journal of nursing research
JID - 7905435
SB  - IM
MH  - Adult
MH  - Anemia, Sickle Cell/psychology/*therapy
MH  - Female
MH  - *Goals
MH  - Hematopoietic Stem Cell Transplantation/methods/psychology/*standards
MH  - Humans
MH  - Illinois
MH  - Interviews as Topic/methods
MH  - Male
MH  - Middle Aged
MH  - Psychometrics/instrumentation/methods
MH  - Qualitative Research
MH  - Quality of Life/*psychology
MH  - Surveys and Questionnaires
PMC - PMC6167199
MID - NIHMS976708
OTO - NOTNLM
OT  - health-related quality of life
OT  - mixed methods
OT  - personal life goals
OT  - sickle cell disease
OT  - stem cell transplantation
EDAT- 2018/04/07 06:00
MHDA- 2019/07/16 06:00
PMCR- 2020/04/01
CRDT- 2018/04/07 06:00
PHST- 2018/04/07 06:00 [pubmed]
PHST- 2019/07/16 06:00 [medline]
PHST- 2018/04/07 06:00 [entrez]
PHST- 2020/04/01 00:00 [pmc-release]
AID - 10.1177/0193945918768277 [doi]
PST - ppublish
SO  - West J Nurs Res. 2019 Apr;41(4):555-575. doi: 10.1177/0193945918768277. Epub 2018 
      Apr 6.