PMID- 29625186 OWN - NLM STAT- MEDLINE DCOM- 20191030 LR - 20191030 IS - 1532-0480 (Electronic) IS - 1532-0464 (Linking) VI - 83 DP - 2018 Jul TI - Bimodal fuzzy analytic hierarchy process (BFAHP) for coronary heart disease risk assessment. PG - 204-216 LID - S1532-0464(18)30064-9 [pii] LID - 10.1016/j.jbi.2018.03.016 [doi] AB - Rooted deeply in medical multiple criteria decision-making (MCDM), risk assessment is very important especially when applied to the risk of being affected by deadly diseases such as coronary heart disease (CHD). CHD risk assessment is a stochastic, uncertain, and highly dynamic process influenced by various known and unknown variables. In recent years, there has been a great interest in fuzzy analytic hierarchy process (FAHP), a popular methodology for dealing with uncertainty in MCDM. This paper proposes a new FAHP, bimodal fuzzy analytic hierarchy process (BFAHP) that augments two aspects of knowledge, probability and validity, to fuzzy numbers to better deal with uncertainty. In BFAHP, fuzzy validity is computed by aggregating the validities of relevant risk factors based on expert knowledge and collective intelligence. By considering both soft and statistical data, we compute the fuzzy probability of risk factors using the Bayesian formulation. In BFAHP approach, these fuzzy validities and fuzzy probabilities are used to construct a reciprocal comparison matrix. We then aggregate fuzzy probabilities and fuzzy validities in a pairwise manner for each risk factor and each alternative. BFAHP decides about being affected and not being affected by ranking of high and low risks. For evaluation, the proposed approach is applied to the risk of being affected by CHD using a real dataset of 152 patients of Iranian hospitals. Simulation results confirm that adding validity in a fuzzy manner can accrue more confidence of results and clinically useful especially in the face of incomplete information when compared with actual results. Applying the proposed BFAHP on CHD risk assessment of the dataset, it yields high accuracy rate above 85% for correct prediction. In addition, this paper recognizes that the risk factors of diastolic blood pressure in men and high-density lipoprotein in women are more important in CHD than other risk factors. CI - Copyright (c) 2018 Elsevier Inc. All rights reserved. FAU - Sabahi, Farnaz AU - Sabahi F AD - Soft Computing Laboratory, Faculty of Electrical and Computer Engineering, Urmia University, Urmia, Iran. Electronic address: f.sabahi@urmia.ac.ir. LA - eng PT - Journal Article DEP - 20180404 PL - United States TA - J Biomed Inform JT - Journal of biomedical informatics JID - 100970413 SB - IM MH - Bayes Theorem MH - Clinical Decision-Making MH - Computer Simulation MH - Coronary Disease/*diagnosis MH - *Diagnosis, Computer-Assisted MH - Female MH - *Fuzzy Logic MH - Humans MH - Male MH - Risk Assessment/*methods MH - Risk Factors MH - Uncertainty OTO - NOTNLM OT - Coronary Heart Disease (CHD) OT - Fuzzy Analytic Hierarchy Process (FAHP) OT - Multi-criteria Decision-Making (MCDM) OT - Validity EDAT- 2018/04/07 06:00 MHDA- 2019/10/31 06:00 CRDT- 2018/04/07 06:00 PHST- 2017/07/31 00:00 [received] PHST- 2018/03/13 00:00 [revised] PHST- 2018/03/31 00:00 [accepted] PHST- 2018/04/07 06:00 [pubmed] PHST- 2019/10/31 06:00 [medline] PHST- 2018/04/07 06:00 [entrez] AID - S1532-0464(18)30064-9 [pii] AID - 10.1016/j.jbi.2018.03.016 [doi] PST - ppublish SO - J Biomed Inform. 2018 Jul;83:204-216. doi: 10.1016/j.jbi.2018.03.016. Epub 2018 Apr 4.