PMID- 29641743
OWN - NLM
STAT- MEDLINE
DCOM- 20181001
LR  - 20220317
IS  - 2013-6463 (Electronic)
IS  - 1575-0620 (Print)
IS  - 1575-0620 (Linking)
VI  - 20
IP  - 1
DP  - 2018
TI  - Prevalence and associated risk factors of latent tuberculosis infection in a 
      Spanish prison.
PG  - 4-10
LID - S1575-06202018000100004 [pii]
AB  - AIM: To determine the prevalence of latent tuberculosis infection (LTI) in a 
      Spanish prison, analyze the main sociodemographic and clinical variables 
      associated with this condition and estimate the percentage of individuals with 
      LTI who have received chemoprophylactic treatment. MATERIALS AND METHODS: 
      Cross-sectional study including inmates hosted in the Madrid VI Prison on 
      16/07/2016. Exclusion criteria: history of tuberculosis; non-updated tuberculin 
      test according to the Tuberculosis Prevention and Control Program in Prisons 
      protocol. Information of the variables was collected from SANIT and SIP programs, 
      and by checking the clinical records of inmates. Description of the participant 
      population and comparison between the frequency of distribution of the 
      independent variables in LTI present and absent groups were performed, the last 
      calculating the p value with Ji2 and Mann-Whitney U tests. Bivariate and 
      multivariate analysis have been carried out with a logistic regression model. 
      RESULTS: 936 individuals have been included. The prevalence of LTI in prison is 
      54.6%. This condition has been linked to the sociodemographic variables age, sex 
      and nationality of origin, being age the one that has shown the strongest 
      association. Among the other factors analyzed, only HCV infection behaves as a 
      predictor of LTI. 30.3% of the individuals with LTI have completed or are 
      receiving chemoprophylactic treatment in the moment of the study. DISCUSSION: LTI 
      prevalence is high in the Spanish current prison population. The results of the 
      study emphasize the relevance of the LTI screening in the prison setting, 
      specially among high risk groups, and point out the need of a greater effort in 
      the indication and completion of the chemoprophylactic treatment.
FAU - Lopez de Goicoechea-Saiz, M E
AU  - Lopez de Goicoechea-Saiz ME
AD  - Facultativo de Sanidad Penitenciaria. Centro Penitenciario Madrid VI. Madrid 
      (Espana).
FAU - Sternberg, F
AU  - Sternberg F
AD  - Subdirector Medico. Centro Penitenciario Madrid VI. Madrid (Espana).
FAU - Portilla-Sogorb, J
AU  - Portilla-Sogorb J
AD  - Jefe de Servicio de Medicina Interna. Hospital General Universitario de Alicante. 
      Alicante (Espana).
LA  - eng
PT  - Journal Article
PL  - Spain
TA  - Rev Esp Sanid Penit
JT  - Revista espanola de sanidad penitenciaria
JID - 101284897
RN  - 0 (Antitubercular Agents)
SB  - IM
CIN - Rev Esp Sanid Penit. 2019;21(2):111-112. PMID: 31642862
MH  - Adult
MH  - Aged
MH  - Antitubercular Agents/therapeutic use
MH  - Cross-Sectional Studies
MH  - Female
MH  - Humans
MH  - Latent Tuberculosis/drug therapy/*epidemiology/etiology
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Prevalence
MH  - Prisoners/*statistics & numerical data
MH  - Prisons
MH  - Risk Factors
MH  - Spain/epidemiology
PMC - PMC6279181
EDAT- 2018/04/12 06:00
MHDA- 2018/10/03 06:00
PMCR- 2018/01/01
CRDT- 2018/04/12 06:00
PHST- 2017/03/17 00:00 [received]
PHST- 2017/07/06 00:00 [accepted]
PHST- 2018/04/12 06:00 [entrez]
PHST- 2018/04/12 06:00 [pubmed]
PHST- 2018/10/03 06:00 [medline]
PHST- 2018/01/01 00:00 [pmc-release]
AID - S1575-06202018000100004 [pii]
AID - 00002 [pii]
PST - ppublish
SO  - Rev Esp Sanid Penit. 2018;20(1):4-10.