PMID- 29651354
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220408
IS  - 2090-6722 (Print)
IS  - 2090-6730 (Electronic)
VI  - 2018
DP  - 2018
TI  - Evolution of Choroidal Neovascularization due to Presumed Ocular Histoplasmosis 
      Syndrome on Multimodal Imaging including Optical Coherence Tomography 
      Angiography.
PG  - 4098419
LID - 10.1155/2018/4098419 [doi]
LID - 4098419
AB  - A 37-year-old Caucasian woman presented with acute decrease in central vision in 
      her right eye and was found to have subfoveal choroidal neovascularization (CNV) 
      due to presumed ocular histoplasmosis syndrome (POHS). Her visual acuity improved 
      from 20/70 to 20/20 at her 6-month follow-up, after 3 consecutive monthly 
      intravitreal bevacizumab injections were initiated at her first visit. Although 
      no CNV activity was seen on fluorescein angiography (FA) or spectral-domain 
      optical coherence tomography (SD-OCT) at her 2-month, 4-month, and 6-month 
      follow-up visits, persistent flow in the CNV lesion was detected on optical 
      coherence tomography angiography (OCTA). OCTA shows persistent vascular flow as 
      well as changes in vascular flow in CNV lesions associated with POHS, indicating 
      the continued presence of patent vessels and changes in these CNV lesions, even 
      when traditional imaging of the lesion with OCT and FA indicates stability of the 
      lesion with no disease activity. Additional cases with longitudinal follow-up are 
      needed to assess how OCTA should be incorporated into clinical practice.
FAU - Liu, T Y Alvin
AU  - Liu TYA
AD  - Retina Division, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, 
      USA.
FAU - Zhang, Alice Yang
AU  - Zhang AY
AD  - Retina Division, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, 
      USA.
AD  - Department of Ophthalmology, University of North Carolina at Chapel Hill, Chapel 
      Hill, NC, USA.
FAU - Wenick, Adam
AU  - Wenick A
AUID- ORCID: 0000-0002-6826-7460
AD  - Retina Division, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, 
      USA.
LA  - eng
PT  - Case Reports
DEP - 20180213
PL  - United States
TA  - Case Rep Ophthalmol Med
JT  - Case reports in ophthalmological medicine
JID - 101581018
PMC - PMC5830978
EDAT- 2018/04/14 06:00
MHDA- 2018/04/14 06:01
PMCR- 2018/02/13
CRDT- 2018/04/14 06:00
PHST- 2017/12/28 00:00 [received]
PHST- 2018/01/21 00:00 [accepted]
PHST- 2018/04/14 06:00 [entrez]
PHST- 2018/04/14 06:00 [pubmed]
PHST- 2018/04/14 06:01 [medline]
PHST- 2018/02/13 00:00 [pmc-release]
AID - 10.1155/2018/4098419 [doi]
PST - epublish
SO  - Case Rep Ophthalmol Med. 2018 Feb 13;2018:4098419. doi: 10.1155/2018/4098419. 
      eCollection 2018.