PMID- 29656266
OWN - NLM
STAT- MEDLINE
DCOM- 20190114
LR  - 20190114
IS  - 1573-2517 (Electronic)
IS  - 0165-0327 (Linking)
VI  - 235
DP  - 2018 Aug 1
TI  - Cortical and subcortical changes in patients with premenstrual syndrome.
PG  - 191-197
LID - S0165-0327(18)30198-8 [pii]
LID - 10.1016/j.jad.2018.04.046 [doi]
AB  - BACKGROUND: Premenstrual syndrome (PMS) is characterized by a series of 
      emotional, physical and behavioral symptoms. Although PMS is related to 
      dysfunctions of the central nervous system, the neuropathological mechanism of 
      PMS still has not been clearly established. The aim of this study is to evaluate 
      potential differences in both cortical thickness and subcortical volumes in PMS 
      patients compared to healthy controls (HCs). METHODS: Twenty PMS patients and 
      twenty HCs underwent a structural magnetic resonance imaging scan and clinical 
      assessment. Cortical thickness and subcortical volumes were computed using the 
      FreeSurfer image analysis suite. Relationships between cortical 
      thickness/subcortical volumes and the daily rating of severity of problems (DRSP) 
      score were then measured in patients. RESULTS: Compared to HCs, PMS patients 
      exhibited reduced cortical thickness in the medial prefrontal cortex (MPFC), 
      orbitofrontal cortex (OFC) and insula, and increased subcortical volumes of the 
      amygdala, thalamus and pallidum. Furthermore, negative correlations were detected 
      between the DRSP and cortical thickness in the anterior cingulate cortex and 
      precuneus. LIMITATIONS: The study is limited by a small sample size and narrow 
      age range of participants. CONCLUSIONS: Our findings indicate that the abnormal 
      morphological changes are mainly implicated in emotional regulation and visceral 
      perception in PMS patients. We hope that our study may contribute to a better 
      understanding of PMS.
CI  - Copyright (c) 2018 Elsevier B.V. All rights reserved.
FAU - Liu, Peng
AU  - Liu P
AD  - Engineering Research Center of Molecular and Neuro Imaging Ministry of Education, 
      Life Sciences Research Center, School of Life Sciences and Technology, Xidian 
      University, Xi'an, Shaanxi 710071, China. Electronic address: 
      liupengphd@gmail.com.
FAU - Wei, Ying
AU  - Wei Y
AD  - Engineering Research Center of Molecular and Neuro Imaging Ministry of Education, 
      Life Sciences Research Center, School of Life Sciences and Technology, Xidian 
      University, Xi'an, Shaanxi 710071, China.
FAU - Fan, Yingying
AU  - Fan Y
AD  - Engineering Research Center of Molecular and Neuro Imaging Ministry of Education, 
      Life Sciences Research Center, School of Life Sciences and Technology, Xidian 
      University, Xi'an, Shaanxi 710071, China.
FAU - Liao, Hai
AU  - Liao H
AD  - Engineering Research Center of Molecular and Neuro Imaging Ministry of Education, 
      Life Sciences Research Center, School of Life Sciences and Technology, Xidian 
      University, Xi'an, Shaanxi 710071, China.
FAU - Wang, Geliang
AU  - Wang G
AD  - Engineering Research Center of Molecular and Neuro Imaging Ministry of Education, 
      Life Sciences Research Center, School of Life Sciences and Technology, Xidian 
      University, Xi'an, Shaanxi 710071, China.
FAU - Li, Ru
AU  - Li R
AD  - Engineering Research Center of Molecular and Neuro Imaging Ministry of Education, 
      Life Sciences Research Center, School of Life Sciences and Technology, Xidian 
      University, Xi'an, Shaanxi 710071, China.
FAU - Duan, Gaoxiong
AU  - Duan G
AD  - Department of Radiology, First Affiliated Hospital, Guangxi University of Chinese 
      Medicine, Nanning, Guangxi 530023, China.
FAU - Deng, Demao
AU  - Deng D
AD  - Department of Radiology, First Affiliated Hospital, Guangxi University of Chinese 
      Medicine, Nanning, Guangxi 530023, China. Electronic address: demaodeng@163.com.
FAU - Qin, Wei
AU  - Qin W
AD  - Engineering Research Center of Molecular and Neuro Imaging Ministry of Education, 
      Life Sciences Research Center, School of Life Sciences and Technology, Xidian 
      University, Xi'an, Shaanxi 710071, China. Electronic address: wqin@xidian.edu.cn.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20180407
PL  - Netherlands
TA  - J Affect Disord
JT  - Journal of affective disorders
JID - 7906073
SB  - IM
MH  - Adult
MH  - Amygdala/diagnostic imaging/pathology
MH  - Case-Control Studies
MH  - Cerebral Cortex/diagnostic imaging/*pathology
MH  - Female
MH  - Gyrus Cinguli/diagnostic imaging/pathology
MH  - Humans
MH  - Magnetic Resonance Imaging/*methods
MH  - Middle Aged
MH  - Organ Size
MH  - Parietal Lobe/diagnostic imaging/pathology
MH  - Premenstrual Syndrome/diagnostic imaging/*pathology
OTO - NOTNLM
OT  - Cortical thickness
OT  - Magnetic resonance imaging
OT  - Morphology
OT  - Premenstrual syndrome
OT  - Subcortical volumes
EDAT- 2018/04/16 06:00
MHDA- 2019/01/15 06:00
CRDT- 2018/04/16 06:00
PHST- 2018/01/30 00:00 [received]
PHST- 2018/03/20 00:00 [revised]
PHST- 2018/04/04 00:00 [accepted]
PHST- 2018/04/16 06:00 [pubmed]
PHST- 2019/01/15 06:00 [medline]
PHST- 2018/04/16 06:00 [entrez]
AID - S0165-0327(18)30198-8 [pii]
AID - 10.1016/j.jad.2018.04.046 [doi]
PST - ppublish
SO  - J Affect Disord. 2018 Aug 1;235:191-197. doi: 10.1016/j.jad.2018.04.046. Epub 
      2018 Apr 7.