PMID- 29660236
OWN - NLM
STAT- MEDLINE
DCOM- 20190304
LR  - 20200225
IS  - 1364-3703 (Electronic)
IS  - 1464-6722 (Print)
IS  - 1364-3703 (Linking)
VI  - 19
IP  - 9
DP  - 2018 Sep
TI  - Oxylipins from both pathogen and host antagonize jasmonic acid-mediated defence 
      via the 9-lipoxygenase pathway in Fusarium verticillioides infection of maize.
PG  - 2162-2176
LID - 10.1111/mpp.12690 [doi]
AB  - Oxylipins are a newly emerging group of signals that serve defence roles or 
      promote virulence. To identify specific host and fungal genes and oxylipins 
      governing the interactions between maize and Fusarium verticillioides, maize 
      wild-type and lipoxygenase3 (lox3) mutant were inoculated with either 
      F. verticillioides wild-type or linoleate-diol-synthase 1-deleted mutant 
      (DeltaFvlds1D). The results showed that lox3 mutants were more resistant to 
      F. verticillioides. The reduced colonization on lox3 was associated with reduced 
      fumonisin production and with a stronger and earlier induction of ZmLOX4, ZmLOX5 
      and ZmLOX12. In addition to the reported defence function of ZmLOX12, we showed 
      that lox4 and lox5 mutants were more susceptible to F. verticillioides and 
      possessed decreased jasmonate levels during infection, suggesting that these 
      genes are essential for jasmonic acid (JA)-mediated defence. Oxylipin profiling 
      revealed a dramatic reduction in fungal linoleate diol synthase 1 (LDS1)-derived 
      oxylipins, especially 8-HpODE (8-hydroperoxyoctadecenoic acid), in infected lox3 
      kernels, indicating the importance of this molecule in virulence. Collectively, 
      we make the following conclusions: (1) LOX3 is a major susceptibility factor 
      induced by fungal LDS1-derived oxylipins to suppress JA-stimulating 9-LOXs; (2) 
      LOX3-mediated signalling promotes the biosynthesis of virulence-promoting 
      oxylipins in the fungus; and (3) both fungal LDS1- and host LOX3-produced 
      oxylipins are essential for the normal infection and colonization processes of 
      maize seed by F. verticillioides.
CI  - (c) 2018 BSPP and John Wiley & Sons Ltd.
FAU - Battilani, Paola
AU  - Battilani P
AD  - Department of Sustainable Crop Production, Universita Cattolica del Sacro Cuore, 
      29122 Piacenza, Italy.
FAU - Lanubile, Alessandra
AU  - Lanubile A
AUID- ORCID: 0000-0002-1868-4469
AD  - Department of Sustainable Crop Production, Universita Cattolica del Sacro Cuore, 
      29122 Piacenza, Italy.
FAU - Scala, Valeria
AU  - Scala V
AD  - CREA-DC, Consiglio per la Ricerca in Agricoltura e l'Analisi dell'Economia 
      Agraria, Research Center for Plant Protection and Certification, 00156 Rome, 
      Italy.
FAU - Reverberi, Massimo
AU  - Reverberi M
AD  - Department of Environmental Biology, University of Rome "Sapienza", 00165 Rome, 
      Italy.
FAU - Gregori, Rossella
AU  - Gregori R
AD  - Department of Sustainable Crop Production, Universita Cattolica del Sacro Cuore, 
      29122 Piacenza, Italy.
FAU - Falavigna, Claudia
AU  - Falavigna C
AD  - Department of Organic and Industrial Chemistry, University of Parma, 43124 Parma, 
      Italy.
FAU - Dall'asta, Chiara
AU  - Dall'asta C
AD  - Department of Organic and Industrial Chemistry, University of Parma, 43124 Parma, 
      Italy.
FAU - Park, Yong-Soon
AU  - Park YS
AD  - BK21 plus program, College of Biological Sciences and Biotechnology, Chungnam 
      National University, Daejeon 34134, South Korea.
FAU - Bennett, John
AU  - Bennett J
AD  - Department of Plant Pathology and Microbiology, Texas A&M University, College 
      Station, TX 77843-2132, USA.
FAU - Borrego, Eli J
AU  - Borrego EJ
AUID- ORCID: 0000-0002-3538-3203
AD  - Department of Plant Pathology and Microbiology, Texas A&M University, College 
      Station, TX 77843-2132, USA.
FAU - Kolomiets, Michael V
AU  - Kolomiets MV
AUID- ORCID: 0000-0003-1038-9534
AD  - Department of Plant Pathology and Microbiology, Texas A&M University, College 
      Station, TX 77843-2132, USA.
LA  - eng
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20180717
PL  - England
TA  - Mol Plant Pathol
JT  - Molecular plant pathology
JID - 100954969
RN  - 0 (Cyclopentanes)
RN  - 0 (Oxylipins)
RN  - 6RI5N05OWW (jasmonic acid)
RN  - EC 1.13.11.12 (Lipoxygenase)
SB  - IM
MH  - Cyclopentanes/*metabolism
MH  - Fusarium/*pathogenicity
MH  - Lipoxygenase/*metabolism
MH  - Oxylipins/*metabolism
MH  - Plant Diseases/*microbiology
MH  - Zea mays/*microbiology
PMC - PMC6638020
OTO - NOTNLM
OT  - Fusarium
OT  - jasmonic acid
OT  - linoleate diol synthase
OT  - maize
OT  - oxylipin cross-talk
OT  - susceptibility genes
EDAT- 2018/04/17 06:00
MHDA- 2019/03/05 06:00
PMCR- 2018/07/17
CRDT- 2018/04/17 06:00
PHST- 2018/02/08 00:00 [received]
PHST- 2018/03/22 00:00 [revised]
PHST- 2018/04/08 00:00 [accepted]
PHST- 2018/04/17 06:00 [pubmed]
PHST- 2019/03/05 06:00 [medline]
PHST- 2018/04/17 06:00 [entrez]
PHST- 2018/07/17 00:00 [pmc-release]
AID - MPP12690 [pii]
AID - 10.1111/mpp.12690 [doi]
PST - ppublish
SO  - Mol Plant Pathol. 2018 Sep;19(9):2162-2176. doi: 10.1111/mpp.12690. Epub 2018 Jul 
      17.