PMID- 2966035
OWN - NLM
STAT- MEDLINE
DCOM- 19880602
LR  - 20190706
IS  - 0090-3493 (Print)
IS  - 0090-3493 (Linking)
VI  - 16
IP  - 5
DP  - 1988 May
TI  - Multicomponent noninvasive physiologic monitoring of circulatory function.
PG  - 482-90
AB  - A multicomponent noninvasive monitoring system for high-risk critically ill 
      patients was developed and tested in a series of 58 high-risk surgical patients. 
      The system was comprised of a thoracic electric bioimpedance (TEB) method for 
      cardiac output estimation, laser-Doppler velocimeter for small vessel flow, 
      transcutaneous oxygen (PtcO2) sensor for tissue oxygenation, pulse oximeter for 
      arterial hemoglobin saturation (SaO2) and finger pressor sensor for arterial 
      pressure. In a series of critically ill patients, this noninvasive system was 
      compared with the widely used invasive monitoring system with systemic and 
      pulmonary artery catheters. Despite theoretical limitations of TEB as a measure 
      of cardiac output, there was a satisfactory correlation (r = .83) of cardiac 
      output measured by thermodilution (TD) and TEB throughout a wide range of severe 
      illnesses. Moreover, changes in TEB cardiac output satisfactorily tracked changes 
      in TD cardiac output (r = .91). There was poor correlation between TD cardiac 
      output and BP or heart rate. The incidence of abruptly changing physiologic 
      patterns was observed with simultaneously monitored invasive and noninvasive 
      systems. Descriptions were made of the central circulation, peripheral perfusion, 
      and pulmonary function; common interactive responses of these circulations were 
      also evaluated. Monitored events defined as abrupt reductions in these variables 
      often occurred from reduced cardiac output, PtcO2 or PtcO2/PaO2 index, and 
      infrequently from unanticipated reductions in SaO2. Recovery from the nadir of 
      the monitored event was associated usually with improvements in flow, PtcO2, or 
      both. Hemodynamic and oxygen transport patterns of a few commonly encountered 
      patterns are described.
FAU - Shoemaker, W C
AU  - Shoemaker WC
AD  - Department of Surgery, King-Drew Medical Center, Los Angeles, CA.
FAU - Appel, P L
AU  - Appel PL
FAU - Kram, H B
AU  - Kram HB
FAU - Nathan, R C
AU  - Nathan RC
FAU - Thompson, J L
AU  - Thompson JL
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Crit Care Med
JT  - Critical care medicine
JID - 0355501
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - *Cardiac Output
MH  - Critical Care/methods
MH  - Evaluation Studies as Topic
MH  - Female
MH  - Hemodynamics
MH  - Humans
MH  - Male
MH  - Microcomputers
MH  - Middle Aged
MH  - Monitoring, Physiologic/*methods
MH  - Mortality
MH  - Oximetry
MH  - Rheology
MH  - Thermodilution
EDAT- 1988/05/01 00:00
MHDA- 1988/05/01 00:01
CRDT- 1988/05/01 00:00
PHST- 1988/05/01 00:00 [pubmed]
PHST- 1988/05/01 00:01 [medline]
PHST- 1988/05/01 00:00 [entrez]
AID - 10.1097/00003246-198805000-00004 [doi]
PST - ppublish
SO  - Crit Care Med. 1988 May;16(5):482-90. doi: 10.1097/00003246-198805000-00004.