PMID- 29660696 OWN - NLM STAT- MEDLINE DCOM- 20180926 LR - 20221207 IS - 1879-0046 (Electronic) IS - 0376-8716 (Linking) VI - 187 DP - 2018 Jun 1 TI - Investigating the correlation between wastewater analysis and roadside drug testing in South Australia. PG - 123-126 LID - S0376-8716(18)30195-9 [pii] LID - 10.1016/j.drugalcdep.2018.02.030 [doi] AB - BACKGROUND: The societal impact of drug use is well known. An example is when drug-intoxicated drivers increase the burden on policing and healthcare services. METHODS: This work presents the correlation of wastewater analysis (using UHPLC-MS/MS) and positive roadside drug testing results for methamphetamine, 3,4-methylenedioxymethamphetamine (MDMA) and cannabis from December 2011-December 2016 in South Australia. RESULTS: Methamphetamine and MDMA showed similar trends between the data sources with matching increases and decreases, respectively. Cannabis was relatively steady based on wastewater analysis, but the roadside drug testing data started to diverge in the final part of the measurement period. CONCLUSIONS: The ability to triangulate data as shown here validates both wastewater analysis and roadside drug testing. This suggests that changes in overall population drug use revealed by WWA is consistent and proportional with changes in drug-driving behaviours. The results show that, at higher levels of drug use as measured by wastewater analysis, there is an increase in drug driving in the community and therefore more strain on health services and police. CI - Copyright (c) 2018 Elsevier B.V. All rights reserved. FAU - Bade, Richard AU - Bade R AD - School of Pharmacy and Medical Sciences, University of South Australia, GPO Box 2471, Adelaide, SA 5001, Australia. FAU - Tscharke, Benjamin J AU - Tscharke BJ AD - School of Pharmacy and Medical Sciences, University of South Australia, GPO Box 2471, Adelaide, SA 5001, Australia. FAU - Longo, Marie AU - Longo M AD - Drug and Alcohol Services South Australia, Adelaide, SA, Australia. FAU - Cooke, Richard AU - Cooke R AD - Drug and Alcohol Services South Australia, Adelaide, SA, Australia. FAU - White, Jason M AU - White JM AD - School of Pharmacy and Medical Sciences, University of South Australia, GPO Box 2471, Adelaide, SA 5001, Australia. FAU - Gerber, Cobus AU - Gerber C AD - School of Pharmacy and Medical Sciences, University of South Australia, GPO Box 2471, Adelaide, SA 5001, Australia. Electronic address: cobus.gerber@unisa.edu.au. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20180410 PL - Ireland TA - Drug Alcohol Depend JT - Drug and alcohol dependence JID - 7513587 RN - 0 (Cannabinoids) RN - 0 (Illicit Drugs) RN - 0 (Waste Water) RN - 44RAL3456C (Methamphetamine) RN - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine) SB - IM MH - Cannabinoids/analysis MH - Cannabis MH - Driving Under the Influence/*statistics & numerical data MH - Humans MH - Illicit Drugs/*analysis MH - Methamphetamine/analysis MH - N-Methyl-3,4-methylenedioxyamphetamine/analysis MH - Police MH - Reproducibility of Results MH - South Australia/epidemiology MH - Substance Abuse Detection/*methods MH - Substance-Related Disorders/diagnosis/epidemiology MH - Tandem Mass Spectrometry MH - Wastewater/*analysis OTO - NOTNLM OT - Australia OT - Illicit drugs OT - Roadside drug testing OT - Wastewater EDAT- 2018/04/17 06:00 MHDA- 2018/09/27 06:00 CRDT- 2018/04/17 06:00 PHST- 2017/11/29 00:00 [received] PHST- 2018/02/10 00:00 [revised] PHST- 2018/02/25 00:00 [accepted] PHST- 2018/04/17 06:00 [pubmed] PHST- 2018/09/27 06:00 [medline] PHST- 2018/04/17 06:00 [entrez] AID - S0376-8716(18)30195-9 [pii] AID - 10.1016/j.drugalcdep.2018.02.030 [doi] PST - ppublish SO - Drug Alcohol Depend. 2018 Jun 1;187:123-126. doi: 10.1016/j.drugalcdep.2018.02.030. Epub 2018 Apr 10.