PMID- 29663530 OWN - NLM STAT- MEDLINE DCOM- 20181106 LR - 20181106 IS - 1439-0507 (Electronic) IS - 0933-7407 (Linking) VI - 61 IP - 8 DP - 2018 Aug TI - Geographical evaluation of Neuroparacoccidioidomycosis and Paracoccidioidomycosis in Southern Brazil. PG - 587-593 LID - 10.1111/myc.12782 [doi] AB - Paracoccidioidomycosis (PCM) is the most prevalent systemic mycosis among immunocompetent patients in Latin America. This study aimed to describe the expansion over time and the geographical distribution of confirmed Neuroparacoccidioidomycosis (NPCM) and PCM cases, and relate it to environmental characteristics such as climate, soil types and coffee crops. This was a retrospective study of autopsy and biopsy reports between 1951 and 2014 from the Medical Pathology Section of the Hospital de Clinicas, Universidade Federal do Parana (UFPR), Curitiba, Southern Brazil. PCM was predominant in male agricultural workers. PCM cases predominated in areas with subtropical climate with hot summers in North West Parana state. NPCM cases were distributed statewide more frequent in rural than metropolitan area. There was no association with climate, soil type, or coffee crop culture. Most of the PCM cases were in the metropolitan area of the capital, chiefly due to migration fluxes. Even though the history is predominantly agricultural, PCM cases were distributed mainly in the metropolitan area of the state capital, there was no association with climate and soil. NPCM cases were numerically more frequent in rural than metropolitan area. CI - (c) 2018 Blackwell Verlag GmbH. FAU - de Almeida, Sergio Monteiro AU - de Almeida SM AUID- ORCID: 0000-0001-5690-105X AD - Medical Pathology Department, School of Medicine, Universidade Federal do Parana, Curitiba, Parana, Brazil. AD - Virology Laboratory, Hospital de Clinicas, Universidade Federal do Parana, Curitiba, Parana, Brazil. AD - Faculdades Pequeno Principe, Curitiba, Parana, Brazil. AD - Instituto de Pesquisa Pele Pequeno Principe, Curitiba, Parana, Brazil. FAU - Salvador, Gabriel L O AU - Salvador GLO AD - Medical Pathology Department, School of Medicine, Universidade Federal do Parana, Curitiba, Parana, Brazil. FAU - Roza, Thiago Henrique AU - Roza TH AD - Medical Pathology Department, School of Medicine, Universidade Federal do Parana, Curitiba, Parana, Brazil. FAU - Izycki, Luis Felipe AU - Izycki LF AD - Medical Pathology Department, School of Medicine, Universidade Federal do Parana, Curitiba, Parana, Brazil. FAU - Dos Santos, Isaias AU - Dos Santos I AD - Medical Pathology Department, School of Medicine, Universidade Federal do Parana, Curitiba, Parana, Brazil. FAU - Aragao, Afonso AU - Aragao A AD - Medical Pathology Department, School of Medicine, Universidade Federal do Parana, Curitiba, Parana, Brazil. FAU - Kulik, Amanda AU - Kulik A AD - Faculdades Pequeno Principe, Curitiba, Parana, Brazil. AD - Instituto de Pesquisa Pele Pequeno Principe, Curitiba, Parana, Brazil. FAU - Muro, Marisol AU - Muro M AD - Mycology Laboratory, Hospital de Clinicas, Universidade Federal do Parana, Curitiba, Parana, Brazil. FAU - Torres, Luis Fernando Bleggi AU - Torres LFB AD - Medical Pathology Department, School of Medicine, Universidade Federal do Parana, Curitiba, Parana, Brazil. AD - Faculdades Pequeno Principe, Curitiba, Parana, Brazil. AD - Instituto de Pesquisa Pele Pequeno Principe, Curitiba, Parana, Brazil. FAU - de Noronha, Lucia AU - de Noronha L AD - Medical Pathology Department, School of Medicine, Universidade Federal do Parana, Curitiba, Parana, Brazil. AD - Laboratorio de Patologia Experimental, Escola de Medicina- Pontificia Universidade Catolica do Parana, Curitiba, Parana, Brazil. LA - eng PT - Journal Article DEP - 20180620 PL - Germany TA - Mycoses JT - Mycoses JID - 8805008 SB - IM MH - Adult MH - Brazil/epidemiology MH - Central Nervous System Fungal Infections/*epidemiology MH - Climate MH - Environmental Exposure MH - Female MH - Humans MH - Male MH - Middle Aged MH - Occupational Exposure MH - Paracoccidioidomycosis/*epidemiology MH - Prevalence MH - Retrospective Studies MH - *Topography, Medical MH - Urban Population OTO - NOTNLM OT - Paracoccidioides spp OT - Neuroparacoccidioidomycosis OT - autopsy OT - biopsy OT - central nervous system OT - environmental factors EDAT- 2018/04/18 06:00 MHDA- 2018/11/07 06:00 CRDT- 2018/04/18 06:00 PHST- 2018/04/03 00:00 [received] PHST- 2018/04/05 00:00 [accepted] PHST- 2018/04/18 06:00 [pubmed] PHST- 2018/11/07 06:00 [medline] PHST- 2018/04/18 06:00 [entrez] AID - 10.1111/myc.12782 [doi] PST - ppublish SO - Mycoses. 2018 Aug;61(8):587-593. doi: 10.1111/myc.12782. Epub 2018 Jun 20.