PMID- 29665228
OWN - NLM
STAT- MEDLINE
DCOM- 20190521
LR  - 20231019
IS  - 1097-0193 (Electronic)
IS  - 1065-9471 (Print)
IS  - 1065-9471 (Linking)
VI  - 39
IP  - 8
DP  - 2018 Aug
TI  - Ultra-high-field fMRI insights on insight: Neural correlates of the Aha!-moment.
PG  - 3241-3252
LID - 10.1002/hbm.24073 [doi]
AB  - Finding creative solutions to difficult problems is a fundamental aspect of human 
      culture and a skill highly needed. However, the exact neural processes underlying 
      creative problem solving remain unclear. Insightful problem solving tasks were 
      shown to be a valid method for investigating one subcomponent of creativity: the 
      Aha!-moment. Finding insightful solutions during a remote associates task (RAT) 
      was found to elicit specific cortical activity changes. Considering the strong 
      affective components of Aha!-moments, as manifested in the subjectively 
      experienced feeling of relief following the sudden emergence of the solution of 
      the problem without any conscious forewarning, we hypothesized the subcortical 
      dopaminergic reward network to be critically engaged during Aha. To investigate 
      those subcortical contributions to insight, we employed ultra-high-field 7 T fMRI 
      during a German Version of the RAT. During this task, subjects were exposed to 
      word triplets and instructed to find a solution word being associated with all 
      the three given words. They were supposed to press a button as soon as they felt 
      confident about their solution without further revision, allowing us to capture 
      the exact event of Aha!-moment. Besides the finding on cortical involvement of 
      the left anterior middle temporal gyrus (aMTG), here we showed for the first time 
      robust subcortical activity changes related to insightful problem solving in the 
      bilateral thalamus, hippocampus, and the dopaminergic midbrain comprising ventral 
      tegmental area (VTA), nucleus accumbens (NAcc), and caudate nucleus. These 
      results shed new light on the affective neural mechanisms underlying insightful 
      problem solving.
CI  - (c) 2018 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc.
FAU - Tik, Martin
AU  - Tik M
AUID- ORCID: 0000-0002-6571-4413
AD  - MR Center of Excellence, Center for Medical Physics and Biomedical Engineering, 
      Medical University of Vienna, Wien, Austria.
FAU - Sladky, Ronald
AU  - Sladky R
AD  - MR Center of Excellence, Center for Medical Physics and Biomedical Engineering, 
      Medical University of Vienna, Wien, Austria.
FAU - Luft, Caroline Di Bernardi
AU  - Luft CDB
AD  - Queen Mary University of London, School of Biological and Chemical Sciences, 
      London, United Kingdom.
AD  - Department of Psychology, Goldsmiths University of London, London, United 
      Kingdom.
FAU - Willinger, David
AU  - Willinger D
AD  - MR Center of Excellence, Center for Medical Physics and Biomedical Engineering, 
      Medical University of Vienna, Wien, Austria.
FAU - Hoffmann, Andre
AU  - Hoffmann A
AD  - MR Center of Excellence, Center for Medical Physics and Biomedical Engineering, 
      Medical University of Vienna, Wien, Austria.
FAU - Banissy, Michael J
AU  - Banissy MJ
AUID- ORCID: 0000-0001-6609-8651
AD  - Queen Mary University of London, School of Biological and Chemical Sciences, 
      London, United Kingdom.
FAU - Bhattacharya, Joydeep
AU  - Bhattacharya J
AUID- ORCID: 0000-0003-3443-9049
AD  - Department of Psychology, Goldsmiths University of London, London, United 
      Kingdom.
FAU - Windischberger, Christian
AU  - Windischberger C
AUID- ORCID: 0000-0002-9944-0190
AD  - MR Center of Excellence, Center for Medical Physics and Biomedical Engineering, 
      Medical University of Vienna, Wien, Austria.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20180417
PL  - United States
TA  - Hum Brain Mapp
JT  - Human brain mapping
JID - 9419065
SB  - IM
MH  - Adult
MH  - Association
MH  - Brain/*diagnostic imaging/*physiology
MH  - Brain Mapping
MH  - *Creativity
MH  - Emotions/physiology
MH  - Female
MH  - Humans
MH  - *Magnetic Resonance Imaging/instrumentation
MH  - Male
MH  - Problem Solving/*physiology
MH  - Young Adult
PMC - PMC6055807
OTO - NOTNLM
OT  - 7 Tesla fMRI
OT  - RAT
OT  - affect
OT  - creativity
OT  - dopamine
OT  - insight
OT  - language processing
OT  - learning
OT  - subcortical
EDAT- 2018/04/18 06:00
MHDA- 2019/05/22 06:00
PMCR- 2018/04/17
CRDT- 2018/04/18 06:00
PHST- 2017/08/25 00:00 [received]
PHST- 2018/03/09 00:00 [revised]
PHST- 2018/03/26 00:00 [accepted]
PHST- 2018/04/18 06:00 [pubmed]
PHST- 2019/05/22 06:00 [medline]
PHST- 2018/04/18 06:00 [entrez]
PHST- 2018/04/17 00:00 [pmc-release]
AID - HBM24073 [pii]
AID - 10.1002/hbm.24073 [doi]
PST - ppublish
SO  - Hum Brain Mapp. 2018 Aug;39(8):3241-3252. doi: 10.1002/hbm.24073. Epub 2018 Apr 
      17.