PMID- 29668862
OWN - NLM
STAT- MEDLINE
DCOM- 20200716
LR  - 20200716
IS  - 1460-2199 (Electronic)
IS  - 1047-3211 (Linking)
VI  - 29
IP  - 5
DP  - 2019 May 1
TI  - Evidence That Default Network Connectivity During Rest Consolidates Social 
      Information.
PG  - 1910-1920
LID - 10.1093/cercor/bhy071 [doi]
AB  - Brain regions engaged during social inference, medial prefrontal cortex (MPFC) 
      and tempoparietal junction (TPJ), are also known to spontaneously engage during 
      rest. While this overlap is well known, the social cognitive function of engaging 
      these regions during rest remains unclear. Building on past research suggesting 
      that new information is committed to memory during rest, we explored whether one 
      function of MPFC and TPJ engagement during rest may be to consolidate new social 
      information. MPFC and TPJ regions significantly increased connectivity during 
      rest after encoding new social information (relative to baseline and post 
      nonsocial encoding rest periods). Moreover, greater connectivity between rTPJ and 
      MPFC, as well as other portions of the default network (vMPFC, anterior temporal 
      lobe, and middle temporal gyrus) during post social encoding rest corresponded 
      with superior social recognition and social associative memory. The tendency to 
      engage MPFC and TPJ during rest may tune people towards social learning.
CI  - (c) The Author(s) 2018. Published by Oxford University Press. All rights reserved. 
      For Permissions, please e-mail: journals.permissions@oup.com.
FAU - Meyer, Meghan L
AU  - Meyer ML
AD  - Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH, 
      USA.
FAU - Davachi, Lila
AU  - Davachi L
AD  - Department of Psychology, Columbia University, New York, NY, USA.
FAU - Ochsner, Kevin N
AU  - Ochsner KN
AD  - Department of Psychology, Columbia University, New York, NY, USA.
FAU - Lieberman, Matthew D
AU  - Lieberman MD
AD  - Department of Psychology, University of California, Los Angeles, CA, USA.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Cereb Cortex
JT  - Cerebral cortex (New York, N.Y. : 1991)
JID - 9110718
RN  - O3FX965V0I (Acetazolamide)
SB  - IM
MH  - Acetazolamide
MH  - Adult
MH  - Brain/*physiology
MH  - Brain Mapping
MH  - Female
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Memory Consolidation/*physiology
MH  - Neural Pathways/physiology
MH  - Parietal Lobe/physiology
MH  - Prefrontal Cortex/physiology
MH  - Social Behavior
MH  - *Social Perception
MH  - Temporal Lobe/physiology
MH  - Young Adult
OTO - NOTNLM
OT  - MPFC
OT  - TPJ
OT  - default network
OT  - memory consolidation
OT  - social cognition
EDAT- 2018/04/19 06:00
MHDA- 2020/07/17 06:00
CRDT- 2018/04/19 06:00
PHST- 2017/08/28 00:00 [received]
PHST- 2018/02/24 00:00 [revised]
PHST- 2018/04/19 06:00 [pubmed]
PHST- 2020/07/17 06:00 [medline]
PHST- 2018/04/19 06:00 [entrez]
AID - 4969845 [pii]
AID - 10.1093/cercor/bhy071 [doi]
PST - ppublish
SO  - Cereb Cortex. 2019 May 1;29(5):1910-1920. doi: 10.1093/cercor/bhy071.