PMID- 29682725
OWN - NLM
STAT- MEDLINE
DCOM- 20181029
LR  - 20221207
IS  - 1365-4632 (Electronic)
IS  - 0011-9059 (Linking)
VI  - 57
IP  - 7
DP  - 2018 Jul
TI  - Atopic labial pigmentation: a new diagnostic feature in Asian patients with 
      atopic dermatitis.
PG  - 817-821
LID - 10.1111/ijd.14010 [doi]
AB  - BACKGROUND: Pigmented lesions on the lips can be caused by physiological or 
      pathological factors, along with exogenous or endogenous factors. Many patients 
      with atopic dermatitis (AD) and labial pigmentation are seen in clinical 
      practice. The aim of our study was to further explore the association of labial 
      pigmentation and AD. METHODS: We performed a retrospective chart review of 
      patients who visited the Department of Dermatology at Kyung Hee Medical Center, 
      Seoul, Korea, from January 1 to December 31, 2016. The study consisted of 178 
      patients with AD and a control group of 178 age- and sex-matched patients without 
      AD. RESULTS: The patients with AD had both a significantly higher prevalence of 
      labial pigmented lesions and a significantly higher number of labial pigmented 
      lesions than was observed in the control group. Moreover, the pigmented lesions 
      were found mainly in the middle section of the upper lip and showed multifocal 
      distribution. The patients with AD and labial pigmentation were significantly 
      younger at the onset of AD, showed a greater association with allergic disorder, 
      and had a higher immunoglobulin E (IgE) level than patients without labial 
      pigmentation. CONCLUSION: Our findings strongly suggest that labial pigmentation 
      occurs in patients with AD. Although labial pigmentation was not present in all 
      patients with AD, this might be a particularly helpful diagnostic feature of AD 
      in Asian patients.
CI  - (c) 2018 The International Society of Dermatology.
FAU - Kang, In-Hye
AU  - Kang IH
AUID- ORCID: 0000-0003-0659-122X
AD  - Department of Dermatology, School of Medicine, Kyung Hee University, Seoul, 
      Korea.
FAU - Jeong, Ki-Heon
AU  - Jeong KH
AD  - Department of Dermatology, School of Medicine, Kyung Hee University, Seoul, 
      Korea.
FAU - Lee, Mu-Hyoung
AU  - Lee MH
AD  - Department of Dermatology, School of Medicine, Kyung Hee University, Seoul, 
      Korea.
FAU - Shin, Min-Kyung
AU  - Shin MK
AUID- ORCID: 0000-0001-9834-7931
AD  - Department of Dermatology, School of Medicine, Kyung Hee University, Seoul, 
      Korea.
LA  - eng
PT  - Journal Article
DEP - 20180423
PL  - England
TA  - Int J Dermatol
JT  - International journal of dermatology
JID - 0243704
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Age of Onset
MH  - Asian People
MH  - Case-Control Studies
MH  - Comorbidity
MH  - Dermatitis, Atopic/blood/*epidemiology
MH  - Female
MH  - Humans
MH  - Immune System Diseases/epidemiology
MH  - Immunoglobulin E/blood
MH  - *Lip
MH  - Male
MH  - Pigmentation Disorders/blood/*epidemiology
MH  - Prevalence
MH  - Republic of Korea/epidemiology
MH  - Retrospective Studies
MH  - Young Adult
EDAT- 2018/04/24 06:00
MHDA- 2018/10/30 06:00
CRDT- 2018/04/24 06:00
PHST- 2017/11/28 00:00 [received]
PHST- 2018/03/22 00:00 [revised]
PHST- 2018/04/02 00:00 [accepted]
PHST- 2018/04/24 06:00 [pubmed]
PHST- 2018/10/30 06:00 [medline]
PHST- 2018/04/24 06:00 [entrez]
AID - 10.1111/ijd.14010 [doi]
PST - ppublish
SO  - Int J Dermatol. 2018 Jul;57(7):817-821. doi: 10.1111/ijd.14010. Epub 2018 Apr 23.