PMID- 29685482
OWN - NLM
STAT- MEDLINE
DCOM- 20190423
LR  - 20190423
IS  - 1532-866X (Electronic)
IS  - 0049-0172 (Linking)
VI  - 48
IP  - 4
DP  - 2019 Feb
TI  - Patient acceptable symptom state and minimal clinically important difference for 
      patient-reported outcomes in systemic sclerosis: A secondary analysis of a 
      randomized controlled trial comparing personalized physical therapy to usual 
      care.
PG  - 694-700
LID - S0049-0172(18)30063-5 [pii]
LID - 10.1016/j.semarthrit.2018.03.013 [doi]
AB  - BACKGROUND: To estimate patient acceptable symptom state (PASS) and minimal 
      clinically important difference (MCID) for patient-reported outcomes in systemic 
      sclerosis (SSc). METHODS: We conducted a secondary analysis of the SCLEREDUC 
      trial, a 12-month randomized controlled trial comparing the efficacy of physical 
      therapy to usual care in 220 SSc patients followed-up from September 2005 to 
      October 2010. Self-rated state and change in patient health at 12 months were 
      assessed by using 2 external anchors extracted from the Medical Outcomes Study 
      36-Item Short-Form. Patients who self-rated their health as "excellent", "very 
      good" or "good" were the PASS group and those who self-rated their health change 
      as "somewhat better" were the MCID group. Main outcomes were the estimates of 
      PASS by using the 75th percentile method and of MCID by using the mean change in 
      scores method for pain and activity limitation. RESULTS: PASS (95% confidence 
      interval) and mean (SD) MCID estimates at 12 months were 53.75 (34.00 to 68.00) 
      and -6.74 (32.02) for the joint-pain visual analog scale (range 0-100), 1.41 
      (1.13 to 1.63) and -0.21 (0.48) for the Health Assessment Questionnaire (HAQ, 
      range 0-3), 1.27 (1.07 to 1.62) and -0.13 (0.45) for the scleroderma HAQ (range 
      0-3), 26.00 (17.00 to 37.00) and -3.38 (9.87) for the Cochin Hand Function Scale 
      (range 0-90), and 19.40 (17.20 to 21.90) and -5.69 (6.79) for the 
      McMaster-Toronto Arthritis Patient Preference Disability Questionnaire (range 
      0-30), respectively. CONCLUSIONS: We provide, for the first time, the PASS and 
      MCID estimates for pain and activity limitation in SSc. TRIAL REGISTRATION: 
      ClinicalTrials.gov Identifier: NCT00318188. First Posted: April 26, 2006.
CI  - Copyright (c) 2018 Elsevier Inc. All rights reserved.
FAU - Daste, Camille
AU  - Daste C
AD  - AP-HP, Service de Reeducation et de Readaptation de l'Appareil Locomoteur et des 
      Pathologies du Rachis, Hopitaux Universitaires Paris Centre-Groupe Hospitalier 
      Cochin, Paris, France; INSERM UMR 1153, Centre de Recherche Epidemiologie et 
      Statistique Paris Sorbonne Cite, ECaMO Team, Paris, France.
FAU - Rannou, Francois
AU  - Rannou F
AD  - AP-HP, Service de Reeducation et de Readaptation de l'Appareil Locomoteur et des 
      Pathologies du Rachis, Hopitaux Universitaires Paris Centre-Groupe Hospitalier 
      Cochin, Paris, France; Sorbonne Paris Cite, Universite Paris Descartes, Faculte 
      de Medecine, Paris, France; INSERM UMR 1124, Laboratoire de Pharmacologie, 
      Toxicologie et Signalisation Cellulaire, Faculte des Sciences Fondamentales et 
      Biomedicales, Centre Universitaire des Saints-Peres, Paris, France.
FAU - Mouthon, Luc
AU  - Mouthon L
AD  - Sorbonne Paris Cite, Universite Paris Descartes, Faculte de Medecine, Paris, 
      France; AP-HP, Service de Medecine Interne, Centre de Reference des Maladies 
      Rares, Hopitaux Universitaires Paris Centre-Groupe Hospitalier Cochin, Paris, 
      France.
FAU - Sanchez, Katherine
AU  - Sanchez K
AD  - AP-HP, Service de Reeducation et de Readaptation de l'Appareil Locomoteur et des 
      Pathologies du Rachis, Hopitaux Universitaires Paris Centre-Groupe Hospitalier 
      Cochin, Paris, France.
FAU - Roren, Alexandra
AU  - Roren A
AD  - AP-HP, Service de Reeducation et de Readaptation de l'Appareil Locomoteur et des 
      Pathologies du Rachis, Hopitaux Universitaires Paris Centre-Groupe Hospitalier 
      Cochin, Paris, France; INSERM UMR 1153, Centre de Recherche Epidemiologie et 
      Statistique Paris Sorbonne Cite, ECaMO Team, Paris, France.
FAU - Tiffreau, Vincent
AU  - Tiffreau V
AD  - Universite Lille 2, Lille, France; Service de Medecine Physique et de 
      Readaptation, CHU de Lille, Lille, France.
FAU - Hachulla, Eric
AU  - Hachulla E
AD  - Universite Lille 2, Lille, France; Service de Medecine Interne, Centre de 
      Reference des Maladies Auto-immunes et Systemiques Rares, CHU de Lille, Lille, 
      France.
FAU - Thoumie, Philippe
AU  - Thoumie P
AD  - Sorbonne Paris Cite, Universite Paris Pierre et Marie Curie, Faculte de Medecine, 
      Paris, France; AP-HP, Service de Medecine Physique et de Readaptation, Hopital 
      Rothschild, Paris, France.
FAU - Cabane, Jean
AU  - Cabane J
AD  - AP-HP, Service de Medecine Interne, Hopital Saint-Antoine, Paris, France.
FAU - Chatelus, Emmanuel
AU  - Chatelus E
AD  - Hopitaux Universitaires de Strasbourg, Service de Rhumatologie, Hopital 
      Hautepierre, Federation de Medecine Translationnelle de Strasbourg, Strasbourg, 
      France; INSERM UMR 1109, Universite de Strasbourg, Strasbourg, France.
FAU - Sibilia, Jean
AU  - Sibilia J
AD  - Hopitaux Universitaires de Strasbourg, Service de Rhumatologie, Hopital 
      Hautepierre, Federation de Medecine Translationnelle de Strasbourg, Strasbourg, 
      France; INSERM UMR 1109, Universite de Strasbourg, Strasbourg, France.
FAU - Poiraudeau, Serge
AU  - Poiraudeau S
AD  - AP-HP, Service de Reeducation et de Readaptation de l'Appareil Locomoteur et des 
      Pathologies du Rachis, Hopitaux Universitaires Paris Centre-Groupe Hospitalier 
      Cochin, Paris, France; INSERM UMR 1153, Centre de Recherche Epidemiologie et 
      Statistique Paris Sorbonne Cite, ECaMO Team, Paris, France; Sorbonne Paris Cite, 
      Universite Paris Descartes, Faculte de Medecine, Paris, France; Institut 
      Federatif de Recherche sur le Handicap, Paris, France.
FAU - Nguyen, Christelle
AU  - Nguyen C
AD  - AP-HP, Service de Reeducation et de Readaptation de l'Appareil Locomoteur et des 
      Pathologies du Rachis, Hopitaux Universitaires Paris Centre-Groupe Hospitalier 
      Cochin, Paris, France; Sorbonne Paris Cite, Universite Paris Descartes, Faculte 
      de Medecine, Paris, France; INSERM UMR 1124, Laboratoire de Pharmacologie, 
      Toxicologie et Signalisation Cellulaire, Faculte des Sciences Fondamentales et 
      Biomedicales, Centre Universitaire des Saints-Peres, Paris, France. Electronic 
      address: christelle.nguyen2@aphp.fr.
LA  - eng
SI  - ClinicalTrials.gov/NCT00318188
PT  - Comparative Study
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20180327
PL  - United States
TA  - Semin Arthritis Rheum
JT  - Seminars in arthritis and rheumatism
JID - 1306053
SB  - IM
MH  - Adult
MH  - Aged
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Minimal Clinically Important Difference
MH  - Patient Reported Outcome Measures
MH  - Patient Satisfaction
MH  - *Physical Therapy Modalities
MH  - Scleroderma, Systemic/drug therapy/*therapy
OTO - NOTNLM
OT  - Minimal clinically important difference
OT  - Patient acceptable symptom state
OT  - Patient-reported outcomes
OT  - Systemic sclerosis
EDAT- 2018/04/25 06:00
MHDA- 2019/04/24 06:00
CRDT- 2018/04/25 06:00
PHST- 2018/02/03 00:00 [received]
PHST- 2018/03/10 00:00 [revised]
PHST- 2018/03/23 00:00 [accepted]
PHST- 2018/04/25 06:00 [pubmed]
PHST- 2019/04/24 06:00 [medline]
PHST- 2018/04/25 06:00 [entrez]
AID - S0049-0172(18)30063-5 [pii]
AID - 10.1016/j.semarthrit.2018.03.013 [doi]
PST - ppublish
SO  - Semin Arthritis Rheum. 2019 Feb;48(4):694-700. doi: 
      10.1016/j.semarthrit.2018.03.013. Epub 2018 Mar 27.