PMID- 29687368 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20180611 LR - 20181114 IS - 1573-4994 (Electronic) IS - 1053-0509 (Linking) VI - 28 IP - 2 DP - 2018 Mar TI - Fluorescent Determination of Succinylcholine Chloride by Naphthalimide/ Stilbazolium Dye subset CP5A. PG - 581-587 LID - 10.1007/s10895-018-2219-2 [doi] AB - Succinylcholine Chloride (SCC), a short-acting neuromuscular relaxant, is non-fluorescent in aqueous solutions. This property makes it impossible to be determined by direct fluorescent method. Naphthalimide dye (NA) exhibits very strong fluorescence emissions in aqueous solution, after complexing with carboxylatopillar[5]arene (CP5A) in aqueous solutions, the fluorescent quenched intensity of complex was observed. On the contraty, stilbazolium dye (SA) exhibits weak fluorescence emissions in aqueous solution, after being included by CP5A, a fluorescence enhancement was observed. However, adding SCC to the NA subset CP5A or SA subset CP5A complex solution led to the recovery of the fluorescence intensity, in the meantime, the color of SA subset CP5A solution changed from dark yellow to light yellow. The competitive supramolecular interaction between SCC, NA and SA for CP5A was studied by spectrofluorometry, (1)H NMR. Herein, a FID (fluorescence indicator displacement) system to detect SCC based on NA subset CP5A and SA subset CP5A complex was developed. FAU - Pan, Qianxia AU - Pan Q AD - Department of Chemistry and Molecular Engineering, School of Nanjing Tech University, Nanjing, China. FAU - He, Zihui AU - He Z AD - Department of Chemistry and Molecular Engineering, School of Nanjing Tech University, Nanjing, China. FAU - Xia, Dongdong AU - Xia D AD - Department of Chemistry and Molecular Engineering, School of Nanjing Tech University, Nanjing, China. FAU - Gu, Xiaomin AU - Gu X AD - Department of College of Food Science and Light Industry, School of Nanjing Tech University, Nanjing, China. FAU - Wang, Haibo AU - Wang H AUID- ORCID: 0000-0002-4682-5580 AD - Department of Chemistry and Molecular Engineering, School of Nanjing Tech University, Nanjing, China. wanghaibo@njut.edu.cn. FAU - Sun, Jie AU - Sun J AD - Department of College of Food Science and Light Industry, School of Nanjing Tech University, Nanjing, China. sunjie5516@126.com. LA - eng GR - 21406108/National Natural Science Foundation of China/ PT - Journal Article DEP - 20180423 PL - Netherlands TA - J Fluoresc JT - Journal of fluorescence JID - 9201341 OTO - NOTNLM OT - CP5A OT - Determination OT - Dye OT - Fluorescence OT - Succinylcholine chloride EDAT- 2018/04/25 06:00 MHDA- 2018/04/25 06:01 CRDT- 2018/04/25 06:00 PHST- 2017/12/29 00:00 [received] PHST- 2018/03/12 00:00 [accepted] PHST- 2018/04/25 06:00 [pubmed] PHST- 2018/04/25 06:01 [medline] PHST- 2018/04/25 06:00 [entrez] AID - 10.1007/s10895-018-2219-2 [pii] AID - 10.1007/s10895-018-2219-2 [doi] PST - ppublish SO - J Fluoresc. 2018 Mar;28(2):581-587. doi: 10.1007/s10895-018-2219-2. Epub 2018 Apr 23.