PMID- 29689466
OWN - NLM
STAT- MEDLINE
DCOM- 20190520
LR  - 20190520
IS  - 1879-0534 (Electronic)
IS  - 0010-4825 (Linking)
VI  - 97
DP  - 2018 Jun 1
TI  - Reconstruction of optical absorption coefficient distribution in intravascular 
      photoacoustic imaging.
PG  - 37-49
LID - S0010-4825(18)30093-3 [pii]
LID - 10.1016/j.compbiomed.2018.04.012 [doi]
AB  - Intravascular photoacoustic (IVPA) imaging can discriminate between normal 
      arterial tissues and atheromatous plaques in images, particularly images of 
      lipid-rich plaques with high spatial resolution and optical contrast. However, 
      conventional IVPA only recovers the deposited optical energy that is the product 
      of the tissue optical absorption coefficient and local optical fluence. Herein, a 
      one-step model-based method for single-wavelength IVPA imaging system is 
      proposed. The proposed method directly reconstructs the optical absorption 
      coefficient from the boundary measurement of acoustic pressure. To obtain the 
      theoretical optical deposition, light illumination and transport in multilayered 
      vessel-wall tissues are numerically modelled with the diffusion approximation to 
      radiative transfer equation. Then, the generation and propagation of 
      photoacoustic (PA) waves in acoustically homogeneous vessel-wall tissues are 
      modelled by using the PA wave equation. The theoretical acoustic pressure series 
      is thus obtained. Finally, the optical absorption coefficient is iteratively 
      updated from an initial guess by minimising a nonlinear least-square error 
      function to quantify the difference between the measured and theoretical acoustic 
      pressure with split Bregman optimisation based on total-variation regularisation. 
      The numerical simulation experiments demonstrated that optical absorption 
      coefficient maps can be directly recovered on the basis of the acoustic boundary 
      measurement of vascular cross-sections. Compared with the optical deposition map, 
      the optical absorption coefficient map can provide more reliable qualitative and 
      quantitative information on the morphology and optical properties of the imaged 
      arteries. The proposed method enables the accurate and reliable evaluation of 
      atheromatous lesions and the early identification of vulnerable plaques.
CI  - Copyright (c) 2018 Elsevier Ltd. All rights reserved.
FAU - Zheng, Sun
AU  - Zheng S
AD  - Department of Electronic and Communication Engineering, North China Electric 
      Power University, Baoding 071003, China. Electronic address: 
      sunzheng_tju@163.com.
FAU - Lan, Zheng
AU  - Lan Z
AD  - Department of Electronic and Communication Engineering, North China Electric 
      Power University, Baoding 071003, China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20180422
PL  - United States
TA  - Comput Biol Med
JT  - Computers in biology and medicine
JID - 1250250
SB  - IM
MH  - Computer Simulation
MH  - Equipment Design
MH  - Humans
MH  - Image Processing, Computer-Assisted/*methods
MH  - Models, Cardiovascular
MH  - Phantoms, Imaging
MH  - Photoacoustic Techniques/*methods
MH  - Plaque, Atherosclerotic/diagnostic imaging
MH  - Ultrasonography, Interventional/*methods
OTO - NOTNLM
OT  - Intravascular photoacoustics (IVPA)
OT  - Inverse problem
OT  - Optical absorption coefficient
OT  - Optical inversion
OT  - Quantitative intravascular photoacoustics (qIVPA)
EDAT- 2018/04/25 06:00
MHDA- 2019/05/21 06:00
CRDT- 2018/04/25 06:00
PHST- 2017/12/27 00:00 [received]
PHST- 2018/04/16 00:00 [revised]
PHST- 2018/04/16 00:00 [accepted]
PHST- 2018/04/25 06:00 [pubmed]
PHST- 2019/05/21 06:00 [medline]
PHST- 2018/04/25 06:00 [entrez]
AID - S0010-4825(18)30093-3 [pii]
AID - 10.1016/j.compbiomed.2018.04.012 [doi]
PST - ppublish
SO  - Comput Biol Med. 2018 Jun 1;97:37-49. doi: 10.1016/j.compbiomed.2018.04.012. Epub 
      2018 Apr 22.