PMID- 29702837
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20191120
IS  - 2212-1102 (Electronic)
IS  - 2212-1099 (Linking)
VI  - 2
IP  - 1
DP  - 2013 May
TI  - Assessment of Adverse Events and Quality of Life of Cancer Patients in a 
      Secondary Level Care, Rural Hospital in South India.
PG  - 103-106
LID - S2212-1099(13)00012-5 [pii]
LID - 10.1016/j.vhri.2013.01.011 [doi]
AB  - OBJECTIVE: To grade adverse events (AEs) occurring after chemotherapy in the 
      cancer patients and to explore the quality-of-life (QOL) findings among 
      posttherapy cancer patients in a rural, secondary level care Indian hospital. 
      METHODS: A cross-sectional study was carried out during a 6-month period in a 
      rural secondary level care hospital situated at Anantapur district in South 
      India. Patient and cancer demographics were collected from the cases treated in 
      the study site. The European Organization for Research and Treatment of Cancer 
      Quality of Life Questionnaire-C30 v 3.0 Telugu (regional language of the study 
      site) module and Common Terminology Criteria for Adverse Events v 4.0 of Cancer 
      Therapy Evaluation Program, USA, were used to assess the QOL and severity grades 
      of AEs, respectively. RESULTS: Most AEs were mild or moderate, with only a few 
      being severe. Insomnia (27.98%), nausea (13.50%), vomiting (12.81%), fatigue 
      (10.90%), and pain (11.68%) were common, with insomnia being the most frequent. 
      The different scores of the QOL scale (functional, symptomatic, financial, and 
      global health status scores) were assessed independently. Among the functional 
      scale parameters, the cognitive and physical functioning scores were good (85.14 
      and 82.79, respectively) and the social, emotional, and role functioning scores 
      were moderate (77.94, 72.30, and 71.65, respectively). The overall effect of 
      symptoms on QOL showed that the pain score was higher and interfered to a higher 
      extent in patients (36.02) and the dyspnea score was the least and occurred to a 
      lesser extent (7.20). But certain variables such as anorexia, for example, showed 
      a greater interquartile range and SD, which implied that it gave a lesser chance 
      for the prediction of results for that particular condition. Financial burden 
      existed to a moderate level on an average in all the patients. CONCLUSIONS: The 
      occurrence and severity of AEs was low, indicating that the patients tolerated 
      and responded well to therapy. The survivorship is yet to be estimated and the 
      life expectancy to be studied by further investigation of the subjects.
CI  - Copyright (c) 2013 International Society for Pharmacoeconomics and Outcomes 
      Research (ISPOR). Published by Elsevier Inc. All rights reserved.
FAU - Sowmya, S K R
AU  - Sowmya SKR
AD  - Department of Pharmacy Practice, Raghavendra Institute of Pharmaceutical 
      Education & Research, Anantapur, AP, India.
FAU - Thomas, Dixon
AU  - Thomas D
AD  - Department of Pharmacy Practice, Raghavendra Institute of Pharmaceutical 
      Education & Research, Anantapur, AP, India. Electronic address: 
      dixon.thomas@gmail.com.
FAU - Zachariah, Seeba
AU  - Zachariah S
AD  - Department of Pharmacy Practice, Raghavendra Institute of Pharmaceutical 
      Education & Research, Anantapur, AP, India.
FAU - Daniel Sunad, Alexander
AU  - Daniel Sunad A
AD  - RDT Hospital, Bathalapalli, Anantapur, AP, India.
LA  - eng
PT  - Journal Article
DEP - 20130315
PL  - United States
TA  - Value Health Reg Issues
JT  - Value in health regional issues
JID - 101592642
OTO - NOTNLM
OT  - CTCAE
OT  - EORTC-QLQ C30
OT  - QOL
OT  - adverse events
OT  - chemotherapy
EDAT- 2013/05/01 00:00
MHDA- 2013/05/01 00:01
CRDT- 2018/04/29 06:00
PHST- 2018/04/29 06:00 [entrez]
PHST- 2013/05/01 00:00 [pubmed]
PHST- 2013/05/01 00:01 [medline]
AID - S2212-1099(13)00012-5 [pii]
AID - 10.1016/j.vhri.2013.01.011 [doi]
PST - ppublish
SO  - Value Health Reg Issues. 2013 May;2(1):103-106. doi: 10.1016/j.vhri.2013.01.011. 
      Epub 2013 Mar 15.