PMID- 2971638 OWN - NLM STAT- MEDLINE DCOM- 19881109 LR - 20190510 IS - 0910-5050 (Print) IS - 1876-4673 (Electronic) IS - 0910-5050 (Linking) VI - 79 IP - 7 DP - 1988 Jul TI - Expression of CR2 (C3d receptor) on the cell membranes of adult T cell leukemia. PG - 805-8 AB - MT-2 cells, which produce human T-cell lymphotropic virus type I (HTLV-I), are known to have a complement receptor. We have established that the complement receptor is CR2 which binds C3d on immune complexes but not CR1. CR2 was also detected on ATL-3I cells but no complement receptor was detected on ATL-1K cells which lack ATL antigen (ATLA). Since CR2 is not detectable on normal T lymphocytes, the presence of CR2 on some ATL cells might suggest that ATL cells were derived from a particular minor lineage of T cells, or HTLV-I has a capacity to induce CR2, which has been demonstrated to be an a-type growth factor for B lymphocytes and to be a receptor for Epstein-Barr virus. FAU - Kai, C AU - Kai C AD - Department of Microbiology, Fukuoka University School of Medicine. FAU - Okada, N AU - Okada N FAU - Okada, H AU - Okada H LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Japan TA - Jpn J Cancer Res JT - Japanese journal of cancer research : Gann JID - 8509412 RN - 0 (Antigens, Differentiation, B-Lymphocyte) RN - 0 (HTLV-I Antigens) RN - 0 (Receptors, Complement) RN - 0 (Receptors, Complement 3d) SB - IM MH - Antigens, Differentiation, B-Lymphocyte/*analysis MH - HTLV-I Antigens/analysis MH - HTLV-I Infections/*immunology MH - Humans MH - Leukemia-Lymphoma, Adult T-Cell/*immunology MH - Receptors, Complement/*analysis MH - Receptors, Complement 3d MH - Rosette Formation PMC - PMC5917600 EDAT- 1988/07/01 00:00 MHDA- 1988/07/01 00:01 PMCR- 1988/07/01 CRDT- 1988/07/01 00:00 PHST- 1988/07/01 00:00 [pubmed] PHST- 1988/07/01 00:01 [medline] PHST- 1988/07/01 00:00 [entrez] PHST- 1988/07/01 00:00 [pmc-release] AID - CAE805 [pii] AID - 10.1111/j.1349-7006.1988.tb00039.x [doi] PST - ppublish SO - Jpn J Cancer Res. 1988 Jul;79(7):805-8. doi: 10.1111/j.1349-7006.1988.tb00039.x.