PMID- 29719035
OWN - NLM
STAT- MEDLINE
DCOM- 20180830
LR  - 20180830
IS  - 1541-8243 (Electronic)
IS  - 0038-4348 (Linking)
VI  - 111
IP  - 4
DP  - 2018 Apr
TI  - Single-Center Retrospective Study of Risk Factors and Predictive Value of 
      Framingham Risk Score of Patients with ST Elevation Myocardial Infarction.
PG  - 226-229
LID - 10.14423/SMJ.0000000000000785 [doi]
AB  - OBJECTIVES: The objective of this study was to identify risk factors and clinical 
      profile of the patients presenting with ST elevation myocardial infarction 
      (STEMI). We further evaluated the utility of the Framingham Risk Score (FRS) in 
      the accurate identification of these patients if used before their coronary 
      event. METHODS: We evaluated the demographic, clinical, and angiographic 
      characteristics of patients admitted with STEMI. We also calculated 
      cardiovascular event risk using the FRS in a subset of patients without prior 
      known coronary artery disease and diabetes mellitus. RESULTS: A total of 44 
      patients, predominantly men (75%) and white (80%), with a mean age of 56 +/- 10 
      years, were included in our analysis. Cigarette smoking was the predominant risk 
      factor (83%) followed by hypertension (77%) and dyslipidemia (68%). The 
      calculated FRS in a subset of patients without prior coronary artery disease or 
      diabetes mellitus was 14.1% +/- 5.8%. Based on the FRS, 8 (36%) patients had a 
      10-year risk >20% and 14 (63%) patients had a 10-year risk between 10% and 20%. 
      CONCLUSIONS: In a series of consecutive patients with STEMI, we observed that 
      high FRS was inadequate in correct identification and risk stratification of the 
      majority of patients who had STEMI. Our study underlines the importance of being 
      familiar with multiple risk scores and choosing the most applicable risk score 
      based on the patient's individual characteristics. In addition, it is important 
      to take into consideration the nontraditional risk factors or measurement of 
      coronary artery calcium as a part of the risk assessment algorithm.
FAU - Ikram, Sohail
AU  - Ikram S
AD  - From the Division of Cardiovascular Medicine, University of Louisville School of 
      Medicine, Louisville, Kentucky.
FAU - Pachika, Ajay
AU  - Pachika A
AD  - From the Division of Cardiovascular Medicine, University of Louisville School of 
      Medicine, Louisville, Kentucky.
FAU - Schuster, Henrike
AU  - Schuster H
AD  - From the Division of Cardiovascular Medicine, University of Louisville School of 
      Medicine, Louisville, Kentucky.
FAU - Ghotra, Aman
AU  - Ghotra A
AD  - From the Division of Cardiovascular Medicine, University of Louisville School of 
      Medicine, Louisville, Kentucky.
FAU - Dotson, Laura
AU  - Dotson L
AD  - From the Division of Cardiovascular Medicine, University of Louisville School of 
      Medicine, Louisville, Kentucky.
FAU - Akbar, Shoaib
AU  - Akbar S
AD  - From the Division of Cardiovascular Medicine, University of Louisville School of 
      Medicine, Louisville, Kentucky.
FAU - Khan, Abdur Rahman
AU  - Khan AR
AD  - From the Division of Cardiovascular Medicine, University of Louisville School of 
      Medicine, Louisville, Kentucky.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - South Med J
JT  - Southern medical journal
JID - 0404522
SB  - IM
MH  - Age Factors
MH  - Aged
MH  - Algorithms
MH  - Angiography/statistics & numerical data
MH  - Demography
MH  - Female
MH  - Humans
MH  - Kentucky/epidemiology
MH  - Middle Aged
MH  - Predictive Value of Tests
MH  - Research Design
MH  - Risk Assessment/*methods
MH  - Risk Factors
MH  - *ST Elevation Myocardial Infarction/diagnosis/epidemiology
MH  - Sex Factors
EDAT- 2018/05/03 06:00
MHDA- 2018/08/31 06:00
CRDT- 2018/05/03 06:00
PHST- 2018/05/03 06:00 [entrez]
PHST- 2018/05/03 06:00 [pubmed]
PHST- 2018/08/31 06:00 [medline]
AID - SMJ50516 [pii]
AID - 10.14423/SMJ.0000000000000785 [doi]
PST - ppublish
SO  - South Med J. 2018 Apr;111(4):226-229. doi: 10.14423/SMJ.0000000000000785.