PMID- 29720509
OWN - NLM
STAT- MEDLINE
DCOM- 20181009
LR  - 20221115
IS  - 1600-0617 (Electronic)
IS  - 0905-9180 (Print)
IS  - 0905-9180 (Linking)
VI  - 27
IP  - 148
DP  - 2018 Jun 30
TI  - State of the art in interstitial pneumonia with autoimmune features: a systematic 
      review on retrospective studies and suggestions for further advances.
LID - 10.1183/16000617.0139-2017 [doi]
LID - 170139
AB  - The term interstitial pneumonia with autoimmune features (IPAF) has been proposed 
      to define patients with interstitial lung disease (ILD) associated with 
      autoimmune signs not classifiable for connective tissue diseases (CTDs). This new 
      definition overcomes previous nomenclatures and provides a uniform structure for 
      prospective studies through specific classification criteria.This work evaluates 
      the characteristics of IPAF patients reported in the literature, to highlight 
      potential limits through a comparative analysis and to suggest better performing 
      classification criteria.Four retrospective studies on the IPAF population have 
      been considered. The study subjects differed in age, sex, smoking habit, ILD 
      pattern and outcomes. Another important difference lies in the diverse items 
      considered in the classification criteria. The retrospective design of the 
      studies and the absence from some of them of a rheumatologist clearly involved in 
      the diagnosis may have influenced the data, but current IPAF criteria seem to 
      include a rather heterogeneous population. To overcome these discrepancies, this 
      review suggests a limitation in the use of single items and the exclusion of 
      extremely specific CTD criteria. This should avoid the definition of IPAF for 
      those diseases at different stages or at early onset. The investigation of a 
      functional or morphological cut-off of pulmonary involvement would be useful.
CI  - Copyright (c)ERS 2018.
FAU - Sambataro, Gianluca
AU  - Sambataro G
AD  - Regional Referral Centre for Rare Lung Diseases, A.O.U. "Policlinico-Vittorio 
      Emanuele" Dept of Clinical and Experimental Medicine, University of Catania, 
      Catania, Italy.
AD  - Rheumatology Outpatients, accredited with the National Health System, Artroreuma 
      srl, Mascalucia, CT, Italy.
FAU - Sambataro, Domenico
AU  - Sambataro D
AD  - Rheumatology Outpatients, accredited with the National Health System, Artroreuma 
      srl, Mascalucia, CT, Italy.
FAU - Torrisi, Sebastiano Emanuele
AU  - Torrisi SE
AD  - Regional Referral Centre for Rare Lung Diseases, A.O.U. "Policlinico-Vittorio 
      Emanuele" Dept of Clinical and Experimental Medicine, University of Catania, 
      Catania, Italy.
FAU - Vancheri, Ada
AU  - Vancheri A
AD  - Regional Referral Centre for Rare Lung Diseases, A.O.U. "Policlinico-Vittorio 
      Emanuele" Dept of Clinical and Experimental Medicine, University of Catania, 
      Catania, Italy.
FAU - Pavone, Mauro
AU  - Pavone M
AD  - Regional Referral Centre for Rare Lung Diseases, A.O.U. "Policlinico-Vittorio 
      Emanuele" Dept of Clinical and Experimental Medicine, University of Catania, 
      Catania, Italy.
FAU - Rosso, Roberta
AU  - Rosso R
AD  - Regional Referral Centre for Rare Lung Diseases, A.O.U. "Policlinico-Vittorio 
      Emanuele" Dept of Clinical and Experimental Medicine, University of Catania, 
      Catania, Italy.
FAU - Schisano, Matteo
AU  - Schisano M
AD  - Regional Referral Centre for Rare Lung Diseases, A.O.U. "Policlinico-Vittorio 
      Emanuele" Dept of Clinical and Experimental Medicine, University of Catania, 
      Catania, Italy.
FAU - Crimi, Claudia
AU  - Crimi C
AD  - Regional Referral Centre for Rare Lung Diseases, A.O.U. "Policlinico-Vittorio 
      Emanuele" Dept of Clinical and Experimental Medicine, University of Catania, 
      Catania, Italy.
FAU - Pignataro, Francesca
AU  - Pignataro F
AD  - Day Hospital of Rheumatology, Dept of Rheumatology, ASST G. Pini-CTO, Milan, 
      Italy.
FAU - Fischer, Aryeh
AU  - Fischer A
AD  - Dept of Medicine, University of Colorado School of Medicine, Denver, CO, USA.
FAU - Del Papa, Nicoletta
AU  - Del Papa N
AD  - Day Hospital of Rheumatology, Dept of Rheumatology, ASST G. Pini-CTO, Milan, 
      Italy.
FAU - Vancheri, Carlo
AU  - Vancheri C
AD  - Regional Referral Centre for Rare Lung Diseases, A.O.U. "Policlinico-Vittorio 
      Emanuele" Dept of Clinical and Experimental Medicine, University of Catania, 
      Catania, Italy.
LA  - eng
PT  - Journal Article
PT  - Review
PT  - Systematic Review
DEP - 20180502
PL  - England
TA  - Eur Respir Rev
JT  - European respiratory review : an official journal of the European Respiratory 
      Society
JID - 9111391
SB  - IM
CIN - Eur Respir Rev. 2018 Jun 27;27(148):. PMID: 29950308
MH  - Aged
MH  - *Autoimmunity
MH  - Female
MH  - Humans
MH  - Lung/*immunology/physiopathology
MH  - Lung Diseases, Interstitial/classification/diagnosis/*immunology/physiopathology
MH  - Male
MH  - Middle Aged
MH  - Predictive Value of Tests
MH  - Prognosis
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Terminology as Topic
PMC - PMC9488748
COIS- Conflict of interest: C. Vancheri reports grants and personal fees from Roche and 
      Boehringer Ingelheim, outside the submitted work. Conflict of interest: A. 
      Fischer reports personal fees (consultancy and steering committee) from 
      Boehringer Ingelheim and F Hoffman La Roche, during the conduct of the study.
EDAT- 2018/05/04 06:00
MHDA- 2018/10/10 06:00
PMCR- 2018/05/02
CRDT- 2018/05/04 06:00
PHST- 2017/12/22 00:00 [received]
PHST- 2018/03/29 00:00 [accepted]
PHST- 2018/05/04 06:00 [entrez]
PHST- 2018/05/04 06:00 [pubmed]
PHST- 2018/10/10 06:00 [medline]
PHST- 2018/05/02 00:00 [pmc-release]
AID - 27/148/170139 [pii]
AID - ERR-0139-2017 [pii]
AID - 10.1183/16000617.0139-2017 [doi]
PST - epublish
SO  - Eur Respir Rev. 2018 May 2;27(148):170139. doi: 10.1183/16000617.0139-2017. Print 
      2018 Jun 30.