PMID- 29721450
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220317
IS  - 2240-4554 (Print)
IS  - 2240-4554 (Electronic)
IS  - 2240-4554 (Linking)
VI  - 7
IP  - 4
DP  - 2017 Oct-Dec
TI  - Multibody modelling of ligamentous and bony stabilizers in the human elbow.
PG  - 493-502
LID - 10.11138/mltj/2017.7.4.493 [doi]
AB  - The elbow ligamentous and bony structures play essential roles in the joint 
      stability. Nevertheless, the contribution of different structures to joint 
      stability is not yet clear and a comprehensive experimental investigation into 
      the ligament and osseous constraints changes in relation to joint motions would 
      be uphill and somehow unattainable, due to the impossibility of obtaining all the 
      possible configurations on the same specimen. Therefore, a predictive tool of the 
      joint behavior after the loss of retentive structures would be helpful in 
      designing reconstructive surgeries and in pre-operative planning. In this work, a 
      multibody model consisting of bones and non-linear ligamentous structures is 
      presented and validated through comparison with experimental data. An accurate 
      geometrical model was equipped with non-linear ligaments bundles between 
      optimized origin and insertion points. The joint function was simulated according 
      to maneuvers accomplished in published experimental studies which explored the 
      posteromedial rotatory instability (PMRI) in coronoid and posterior medial 
      collateral ligament (PB) deficient elbows. Moreover, a complete design of 
      experiments (DOE) was explored, investigating the influence of the elbow flexion 
      degree, of the coronoid process and of the medial collateral ligaments (MCL) 
      structures (anterior and posterior bundles) in the elbow joint opening. The 
      implemented computational model accurately predicted the joint behavior with 
      intact and deficient stabilizing structures at each flexion degree, and 
      highlighted the statistically significant influence of the MCL structures 
      (P<0.05) on the elbow stability. The predictive ability of this multibody elbow 
      joint model let foresee that future investigations under different loading 
      scenarios and injured or surgically reconstructed states could be effectively 
      simulated, helping the ligaments reconstruction optimization in terms of bone 
      tunnel localizations and grafts pre-loading. LEVEL OF EVIDENCE: V.
FAU - Terzini, Mara
AU  - Terzini M
AD  - Department of Mechanical and Aerospace Engineering, Politecnico di Torino, 
      Torino, Italy.
FAU - Zanetti, Elisabetta Maria
AU  - Zanetti EM
AD  - Department of Engineering, University of Perugia, Perugia, Italy.
FAU - Audenino, Alberto Luigi
AU  - Audenino AL
AD  - Department of Mechanical and Aerospace Engineering, Politecnico di Torino, 
      Torino, Italy.
FAU - Putame, Giovanni
AU  - Putame G
AD  - Department of Mechanical and Aerospace Engineering, Politecnico di Torino, 
      Torino, Italy.
FAU - Gastaldi, Laura
AU  - Gastaldi L
AD  - Department of Mechanical and Aerospace Engineering, Politecnico di Torino, 
      Torino, Italy.
FAU - Pastorelli, Stefano
AU  - Pastorelli S
AD  - Department of Mechanical and Aerospace Engineering, Politecnico di Torino, 
      Torino, Italy.
FAU - Panero, Elisa
AU  - Panero E
AD  - Department of Mechanical and Aerospace Engineering, Politecnico di Torino, 
      Torino, Italy.
FAU - Sard, Arman
AU  - Sard A
AD  - Hand Surgery Division, AOU CTO, Turin, Italy.
FAU - Bignardi, Cristina
AU  - Bignardi C
AD  - Department of Mechanical and Aerospace Engineering, Politecnico di Torino, 
      Torino, Italy.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20180416
PL  - Italy
TA  - Muscles Ligaments Tendons J
JT  - Muscles, ligaments and tendons journal
JID - 101600853
PMC - PMC5908325
OTO - NOTNLM
OT  - coronoid process
OT  - elbow stability
OT  - medial collateral ligaments
OT  - multibody model
EDAT- 2018/05/04 06:00
MHDA- 2018/05/04 06:01
PMCR- 2018/04/16
CRDT- 2018/05/04 06:00
PHST- 2018/05/04 06:00 [entrez]
PHST- 2018/05/04 06:00 [pubmed]
PHST- 2018/05/04 06:01 [medline]
PHST- 2018/04/16 00:00 [pmc-release]
AID - 493-502 [pii]
AID - 10.11138/mltj/2017.7.4.493 [doi]
PST - epublish
SO  - Muscles Ligaments Tendons J. 2018 Apr 16;7(4):493-502. doi: 
      10.11138/mltj/2017.7.4.493. eCollection 2017 Oct-Dec.