PMID- 29722267 OWN - NLM STAT- MEDLINE DCOM- 20181126 LR - 20181126 IS - 1130-0108 (Print) IS - 1130-0108 (Linking) VI - 110 IP - 7 DP - 2018 Jul TI - Recommendations to report and interpret HLA genetic findings in coeliac disease. PG - 458-461 LID - 10.17235/reed.2018.5269/2017 [doi] AB - Coeliac disease (CD) is a chronic autoimmune enteropathy triggered by gluten and related prolamines in genetically predisposed individuals. Although CD is a polygenic disease, there is a strong association with genes of the human leukocyte antigen (HLA) region. Most patients present the HLA-DQ2 heterodimer, specifically the DQ2.5 isoform, which is present in around 90-96% of patients of European ancestry. FAU - Nunez, Concepcion AU - Nunez C AD - Laboratorio de Genetica d Enfermedades Autoinmunes, Hospital Clinico San Carlos, Espana. FAU - Garrote, Jose Antonio AU - Garrote JA AD - Hospital Universitario Rio Hortega. FAU - Arranz, Eduardo AU - Arranz E AD - Universidad de Valladolid-CSIC. FAU - Bilbao, Jose Ramon AU - Bilbao JR AD - Universidad del Pais Vasco; BioCruces. FAU - Fernandez Banares, Fernando AU - Fernandez Banares F AD - Hospital Universitari Mutua Terrassa. FAU - Jimenez, Juana AU - Jimenez J AD - Hospital Universitario Severo Ochoa. FAU - Perucho, Teresa AU - Perucho T AD - Genyca Innova. FAU - Ruiz Casares, Eva AU - Ruiz Casares E AD - Genyca Innova. FAU - Sanchez-Valverde, Felix AU - Sanchez-Valverde F AD - Complejo Hospitalario de Navarra, Pamplona . FAU - Serrano, Juan I AU - Serrano JI AD - Asociacion de Celiacos y Sensibles al Gluten . LA - eng PT - Guideline PT - Journal Article PL - Spain TA - Rev Esp Enferm Dig JT - Revista espanola de enfermedades digestivas JID - 9007566 RN - 0 (HLA Antigens) SB - IM MH - Celiac Disease/*diagnosis/*genetics MH - Genetic Predisposition to Disease MH - HLA Antigens/*genetics MH - Humans EDAT- 2018/05/04 06:00 MHDA- 2018/11/27 06:00 CRDT- 2018/05/04 06:00 PHST- 2018/05/04 06:00 [pubmed] PHST- 2018/11/27 06:00 [medline] PHST- 2018/05/04 06:00 [entrez] AID - 10.17235/reed.2018.5269/2017 [doi] PST - ppublish SO - Rev Esp Enferm Dig. 2018 Jul;110(7):458-461. doi: 10.17235/reed.2018.5269/2017.