PMID- 29722861 OWN - NLM STAT- MEDLINE DCOM- 20190409 LR - 20190409 IS - 1532-2092 (Electronic) IS - 1099-5129 (Linking) VI - 20 IP - suppl_2 DP - 2018 May 1 TI - Early and long-term outcomes after manual and remote magnetic navigation-guided catheter ablation for ventricular tachycardia. PG - ii11-ii21 LID - 10.1093/europace/euy057 [doi] AB - AIMS: Remote magnetic navigation (RMN) is a safe and effective means of performing ventricular tachycardia (VT) ablation. It may have advantages over manual catheter ablation due to ease of manoeuvrability and catheter stability. We sought to compare the safety and efficacy of RMN vs. manual VT ablation. METHODS AND RESULTS: Retrospective study of procedural outcomes of 139 consecutive VT ablation procedures (69 RMN, 70 manual ablation) in 113 patients between 2009 and 2015 was performed. Remote magnetic navigation was associated with overall higher acute procedural success (80% vs. 60%, P = 0.01), with a trend to fewer major complications (3% vs. 9% P = 0.09). Seventy-nine patients were followed up for a median of 17.0 [interquartile range (IQR) 3.0-41.0] months for the RMN group and 15.5 (IQR 6.5-30.0) months for manual ablation group. In the ischaemic cardiomyopathy subgroup, RMN was associated with longer survival from the composite endpoint of VT recurrence leading to defibrillator shock, re-hospitalization or repeat catheter ablation and all-cause mortality; single-procedure adjusted hazard ratio (HR) 0.240 (95% CI 0.070-0.821) P = 0.023, multi-procedure HR 0.170 (95% CI 0.046-0.632) P = 0.002. In patients with implanted defibrillators, multi-procedure VT-free survival was superior with RMN, HR 0.199 (95% CI 0.060-0.657) P = 0.003. CONCLUSION: Remote magnetic navigation may improve clinical outcomes after catheter ablation of VT in patients with ischaemic cardiomyopathy. Further prospective clinical studies are required to confirm these findings. FAU - Qian, Pierre AU - Qian P AD - Department of Cardiology, Westmead Hospital, Cnr of Hawkesbury and Darcy Rd, Westmead, Sydney, NSW 2145, Australia. AD - Sydney Medical School, University of Sydney, Sydney, Australia. FAU - De Silva, Kasun AU - De Silva K AD - Department of Cardiology, Westmead Hospital, Cnr of Hawkesbury and Darcy Rd, Westmead, Sydney, NSW 2145, Australia. FAU - Kumar, Saurabh AU - Kumar S AD - Department of Cardiology, Westmead Hospital, Cnr of Hawkesbury and Darcy Rd, Westmead, Sydney, NSW 2145, Australia. FAU - Nadri, Fazlur AU - Nadri F AD - Department of Cardiology, Westmead Hospital, Cnr of Hawkesbury and Darcy Rd, Westmead, Sydney, NSW 2145, Australia. AD - Sydney Medical School, University of Sydney, Sydney, Australia. FAU - Samanta, Rahul AU - Samanta R AD - Department of Cardiology, Westmead Hospital, Cnr of Hawkesbury and Darcy Rd, Westmead, Sydney, NSW 2145, Australia. AD - Sydney Medical School, University of Sydney, Sydney, Australia. FAU - Bhaskaran, Abhishek AU - Bhaskaran A AD - Department of Cardiology, Westmead Hospital, Cnr of Hawkesbury and Darcy Rd, Westmead, Sydney, NSW 2145, Australia. AD - Sydney Medical School, University of Sydney, Sydney, Australia. FAU - Ross, David AU - Ross D AD - Department of Cardiology, Westmead Hospital, Cnr of Hawkesbury and Darcy Rd, Westmead, Sydney, NSW 2145, Australia. AD - Sydney Medical School, University of Sydney, Sydney, Australia. FAU - Sivagangabalan, Gopal AU - Sivagangabalan G AD - Department of Cardiology, Westmead Hospital, Cnr of Hawkesbury and Darcy Rd, Westmead, Sydney, NSW 2145, Australia. AD - School of Medicine, University of Notre Dame Australia, Sydney, Australia. FAU - Cooper, Mark AU - Cooper M AD - Department of Cardiology, Westmead Hospital, Cnr of Hawkesbury and Darcy Rd, Westmead, Sydney, NSW 2145, Australia. FAU - Kizana, Eddy AU - Kizana E AD - Department of Cardiology, Westmead Hospital, Cnr of Hawkesbury and Darcy Rd, Westmead, Sydney, NSW 2145, Australia. AD - Sydney Medical School, University of Sydney, Sydney, Australia. FAU - Davis, Lloyd AU - Davis L AD - Department of Cardiology, Westmead Hospital, Cnr of Hawkesbury and Darcy Rd, Westmead, Sydney, NSW 2145, Australia. AD - School of Medicine, Western Sydney University, Sydney, Australia. FAU - Denniss, Alan Robert AU - Denniss AR AD - Department of Cardiology, Westmead Hospital, Cnr of Hawkesbury and Darcy Rd, Westmead, Sydney, NSW 2145, Australia. AD - Sydney Medical School, University of Sydney, Sydney, Australia. AD - School of Medicine, Western Sydney University, Sydney, Australia. FAU - Thiagalingam, Aravinda AU - Thiagalingam A AD - Department of Cardiology, Westmead Hospital, Cnr of Hawkesbury and Darcy Rd, Westmead, Sydney, NSW 2145, Australia. AD - Sydney Medical School, University of Sydney, Sydney, Australia. FAU - Thomas, Stuart AU - Thomas S AD - Department of Cardiology, Westmead Hospital, Cnr of Hawkesbury and Darcy Rd, Westmead, Sydney, NSW 2145, Australia. AD - Sydney Medical School, University of Sydney, Sydney, Australia. FAU - Kovoor, Pramesh AU - Kovoor P AD - Department of Cardiology, Westmead Hospital, Cnr of Hawkesbury and Darcy Rd, Westmead, Sydney, NSW 2145, Australia. AD - Sydney Medical School, University of Sydney, Sydney, Australia. LA - eng PT - Comparative Study PT - Journal Article PL - England TA - Europace JT - Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology JID - 100883649 SB - IM MH - Action Potentials MH - Adult MH - Aged MH - Cardiac Catheterization/adverse effects/instrumentation/*methods/mortality MH - Cardiac Catheters MH - Catheter Ablation/adverse effects/instrumentation/*methods/mortality MH - Electrophysiologic Techniques, Cardiac MH - Female MH - Heart Rate MH - Humans MH - Magnetics/instrumentation/*methods MH - Magnets MH - Male MH - Middle Aged MH - Recurrence MH - Remote Sensing Technology/instrumentation/*methods MH - Retrospective Studies MH - Risk Factors MH - Surgery, Computer-Assisted/adverse effects/instrumentation/*methods/mortality MH - Tachycardia, Ventricular/diagnosis/mortality/physiopathology/*surgery MH - Time Factors MH - Treatment Outcome EDAT- 2018/05/04 06:00 MHDA- 2019/04/10 06:00 CRDT- 2018/05/04 06:00 PHST- 2017/10/09 00:00 [received] PHST- 2018/03/12 00:00 [accepted] PHST- 2018/05/04 06:00 [entrez] PHST- 2018/05/04 06:00 [pubmed] PHST- 2019/04/10 06:00 [medline] AID - 4983091 [pii] AID - 10.1093/europace/euy057 [doi] PST - ppublish SO - Europace. 2018 May 1;20(suppl_2):ii11-ii21. doi: 10.1093/europace/euy057.