PMID- 29737055 OWN - NLM STAT- MEDLINE DCOM- 20190118 LR - 20190118 IS - 1672-173X (Print) IS - 1672-173X (Linking) VI - 49 IP - 2 DP - 2018 Mar TI - [A Retrospective Analysis of Clinical Features of Interstitial Pneumonia with Autoimmune Features]. PG - 174-178 AB - OBJECTIVE: To analyze the clinical features of interstitial pneumonia with autoimmune features (IPAF) and the correlation between them. METHODS: We respectively analyzed the patients with interstitial lung disease (ILD) admitted in our hospital from January 2014 to January 2017. The patients who met all priori requirements and at least one feature of one domain were recuited, and the clinical features and autoimmune diseases related prognosis were analyzed. RESULTS: There were 90 patients recruited,including 38 patients completely met IPAF classification criteria and 52 patients who incompletely met. The average age was (62.34+/-14.98) yr.. The pneumonia pattern of complete IPAF patients was non-specific interstitial pneumonia (NSIP), while it was usually interstitial pneumonia (UIP) in the incomplete IPAF patients. During follow-up,11 patients were diagnosed with autoimmune diseases (4 with complete IPAF,and 7 with incomplete IPAF) . According to Cox regression analysis,completely meet the criteria of IPAF was related to the relapse of disease. CONCLUSION: There exist relation between IPAF and autoimmune diseases. The patients with IPAFmay finally develop into autoimmune diseases. The IPAF classification criteria provide basic structure for this disease,but the limitation of the criteria call for revising by more clinical trials. CI - Copyright(c) by Editorial Board of Journal of Sichuan University (Medical Science Edition). FAU - Cui, Bei-Bei AU - Cui BB AD - Department of Rheumatology and Immunology,West China Hospital,Sichuan University,Chengdu 610041,China. FAU - Wu, Yang AU - Wu Y AD - Department of Rheumatology and Immunology,West China Hospital,Sichuan University,Chengdu 610041,China. FAU - Liu, Huan AU - Liu H AD - Department of Rheumatology and Immunology,West China Hospital,Sichuan University,Chengdu 610041,China. FAU - Chen, Yi-Dan AU - Chen YD AD - Department of Rheumatology and Immunology,West China Hospital,Sichuan University,Chengdu 610041,China. FAU - Xie, Qi-Bing AU - Xie QB AD - Department of Rheumatology and Immunology,West China Hospital,Sichuan University,Chengdu 610041,China. FAU - Yin, Geng AU - Yin G AD - Department of International Medical Center/Greneral Practice,West China Hospital,Sichuan University,Chengdu 610041,China. LA - chi PT - Journal Article PL - China TA - Sichuan Da Xue Xue Bao Yi Xue Ban JT - Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition JID - 101162609 SB - IM MH - Aged MH - Autoimmune Diseases/*complications MH - Humans MH - Lung Diseases, Interstitial/*complications MH - Middle Aged MH - Prognosis MH - Retrospective Studies MH - Tomography, X-Ray Computed OTO - NOTNLM OT - Autoimmune antibodies OT - Autoimmune diseases OT - Classification criteria OT - Interstitial pneumonia with autoimmune features EDAT- 2018/05/08 06:00 MHDA- 2019/01/19 06:00 CRDT- 2018/05/09 06:00 PHST- 2018/05/09 06:00 [entrez] PHST- 2018/05/08 06:00 [pubmed] PHST- 2019/01/19 06:00 [medline] PST - ppublish SO - Sichuan Da Xue Xue Bao Yi Xue Ban. 2018 Mar;49(2):174-178.