PMID- 29763669
OWN - NLM
STAT- MEDLINE
DCOM- 20181123
LR  - 20181123
IS  - 1873-0442 (Electronic)
IS  - 1477-8939 (Linking)
VI  - 25
DP  - 2018 Sep-Oct
TI  - Travel-related health problems in the immunocompromised traveller: An exploratory 
      study.
PG  - 50-57
LID - S1477-8939(18)30095-4 [pii]
LID - 10.1016/j.tmaid.2018.05.005 [doi]
AB  - BACKGROUND: Immunocompromised travellers (ICTs) are at increased risk of 
      travel-related health problems. Therefore, they are advised to attend specialised 
      pre-travel clinics for advice on vaccination, malaria chemoprophylaxis and 
      on-demand antibiotics. However, studies yield conflicting data regarding 
      travel-related health problems encountered by ICTs; questioning the rationale for 
      certain advices, and particularly the advice of on-demand antibiotics. OBJECTIVE: 
      To evaluate self-reported travel-related health problems, antibiotic use, medical 
      visits and risk behaviours in ICTs and controls. METHODS: We conducted a 
      questionnaire-based observational study with pilot character. We recruited 
      participants from a (medical) pre-travel clinic. Telephone interviews were 
      conducted 2-4 weeks post-travelling, applying a structured questionnaire. 
      RESULTS: We included 30 ICTs and 30 controls. More ICTs than controls reported 
      travel-related health problems, antibiotic use and medical visits, although not 
      statistically significant. Travellers' diarrhoea appeared to be more severe in 
      ICTs. Furthermore one ICT was hospitalized post-travel due to pneumonia. Of ICTs, 
      2/30 (7%) used on demand antibiotics while not indicated (according to the 
      protocol of the Dutch national coordinating centre for travel advice or 
      prescribed by a physician). Reversely, 6/30 (20%) did not use on demand 
      antibiotics while actually indicated according to this protocol. DISCUSSION: Our 
      findings substantiate the recommendation of on demand antibiotics. However, ICTs 
      did often not use on demand antibiotics correctly; they therefore need very 
      careful instructions.
CI  - Copyright (c) 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.
FAU - van Aalst, Marielle
AU  - van Aalst M
AD  - Centre of Tropical Medicine and Travel Medicine, Department of Infectious 
      Diseases, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 
      1100AZ, Amsterdam, The Netherlands.
FAU - van Ruissen, Marella C E
AU  - van Ruissen MCE
AD  - Centre of Tropical Medicine and Travel Medicine, Department of Infectious 
      Diseases, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 
      1100AZ, Amsterdam, The Netherlands.
FAU - Verhoeven, Roos
AU  - Verhoeven R
AD  - Centre of Tropical Medicine and Travel Medicine, Department of Infectious 
      Diseases, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 
      1100AZ, Amsterdam, The Netherlands.
FAU - de Bree, Godelieve J
AU  - de Bree GJ
AD  - Centre of Tropical Medicine and Travel Medicine, Department of Infectious 
      Diseases, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 
      1100AZ, Amsterdam, The Netherlands; Amsterdam Institute for Global Health and 
      Development, Paasheuvelweg 25, 1105BP, Amsterdam, The Netherlands.
FAU - Goorhuis, Abraham
AU  - Goorhuis A
AD  - Centre of Tropical Medicine and Travel Medicine, Department of Infectious 
      Diseases, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 
      1100AZ, Amsterdam, The Netherlands.
FAU - Grobusch, Martin P
AU  - Grobusch MP
AD  - Centre of Tropical Medicine and Travel Medicine, Department of Infectious 
      Diseases, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 
      1100AZ, Amsterdam, The Netherlands. Electronic address: m.p.grobusch@amc.uva.nl.
LA  - eng
PT  - Journal Article
DEP - 20180512
PL  - Netherlands
TA  - Travel Med Infect Dis
JT  - Travel medicine and infectious disease
JID - 101230758
RN  - 0 (Anti-Bacterial Agents)
SB  - IM
MH  - Adult
MH  - Anti-Bacterial Agents/administration & dosage
MH  - Data Collection
MH  - Diarrhea/prevention & control
MH  - Humans
MH  - *Immunocompromised Host
MH  - Middle Aged
MH  - Risk Factors
MH  - Surveys and Questionnaires
MH  - *Travel
MH  - *Travel-Related Illness
MH  - Vaccination
OTO - NOTNLM
OT  - Immunocompromised traveller
OT  - Immunodeficiency
OT  - Travel
OT  - Travellers' diarrhoea
EDAT- 2018/05/16 06:00
MHDA- 2018/11/24 06:00
CRDT- 2018/05/16 06:00
PHST- 2018/03/21 00:00 [received]
PHST- 2018/05/03 00:00 [revised]
PHST- 2018/05/09 00:00 [accepted]
PHST- 2018/05/16 06:00 [pubmed]
PHST- 2018/11/24 06:00 [medline]
PHST- 2018/05/16 06:00 [entrez]
AID - S1477-8939(18)30095-4 [pii]
AID - 10.1016/j.tmaid.2018.05.005 [doi]
PST - ppublish
SO  - Travel Med Infect Dis. 2018 Sep-Oct;25:50-57. doi: 10.1016/j.tmaid.2018.05.005. 
      Epub 2018 May 12.