PMID- 29765477 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240325 IS - 1871-4080 (Print) IS - 1871-4099 (Electronic) IS - 1871-4080 (Linking) VI - 12 IP - 3 DP - 2018 Jun TI - Detecting epileptic seizure with different feature extracting strategies using robust machine learning classification techniques by applying advance parameter optimization approach. PG - 271-294 LID - 10.1007/s11571-018-9477-1 [doi] AB - Epilepsy is a neurological disorder produced due to abnormal excitability of neurons in the brain. The research reveals that brain activity is monitored through electroencephalogram (EEG) of patients suffered from seizure to detect the epileptic seizure. The performance of EEG detection based epilepsy require feature extracting strategies. In this research, we have extracted varying features extracting strategies based on time and frequency domain characteristics, nonlinear, wavelet based entropy and few statistical features. A deeper study was undertaken using novel machine learning classifiers by considering multiple factors. The support vector machine kernels are evaluated based on multiclass kernel and box constraint level. Likewise, for K-nearest neighbors (KNN), we computed the different distance metrics, Neighbor weights and Neighbors. Similarly, the decision trees we tuned the paramours based on maximum splits and split criteria and ensemble classifiers are evaluated based on different ensemble methods and learning rate. For training/testing tenfold Cross validation was employed and performance was evaluated in form of TPR, NPR, PPV, accuracy and AUC. In this research, a deeper analysis approach was performed using diverse features extracting strategies using robust machine learning classifiers with more advanced optimal options. Support Vector Machine linear kernel and KNN with City block distance metric give the overall highest accuracy of 99.5% which was higher than using the default parameters for these classifiers. Moreover, highest separation (AUC = 0.9991, 0.9990) were obtained at different kernel scales using SVM. Additionally, the K-nearest neighbors with inverse squared distance weight give higher performance at different Neighbors. Moreover, to distinguish the postictal heart rate oscillations from epileptic ictal subjects, and highest performance of 100% was obtained using different machine learning classifiers. FAU - Hussain, Lal AU - Hussain L AUID- ORCID: 0000-0003-1103-4938 AD - 1Quality Enhancement Cell (QEC), The University of Azad Jammu and Kashmir, City Campus, Muzaffarabad, Azad Kashmir 13100 Pakistan. ISNI: 0000 0001 0699 3419. GRID: grid.413058.b AD - 2Department of Computer Science and IT, The University of Azad Jammu and Kashmir, City Campus, Muzaffarabad, 13100 Pakistan. ISNI: 0000 0001 0699 3419. GRID: grid.413058.b LA - eng PT - Journal Article DEP - 20180125 PL - Netherlands TA - Cogn Neurodyn JT - Cognitive neurodynamics JID - 101306907 PMC - PMC5943212 OTO - NOTNLM OT - Classification OT - Decision tree OT - Ensemble classifier OT - Epilepsy OT - K-nearest neighbors OT - Seizure detection OT - Support vector machine EDAT- 2018/05/17 06:00 MHDA- 2018/05/17 06:01 PMCR- 2019/06/01 CRDT- 2018/05/17 06:00 PHST- 2017/10/09 00:00 [received] PHST- 2017/12/01 00:00 [revised] PHST- 2018/01/18 00:00 [accepted] PHST- 2018/05/17 06:00 [entrez] PHST- 2018/05/17 06:00 [pubmed] PHST- 2018/05/17 06:01 [medline] PHST- 2019/06/01 00:00 [pmc-release] AID - 9477 [pii] AID - 10.1007/s11571-018-9477-1 [doi] PST - ppublish SO - Cogn Neurodyn. 2018 Jun;12(3):271-294. doi: 10.1007/s11571-018-9477-1. Epub 2018 Jan 25.