PMID- 29768089 OWN - NLM STAT- MEDLINE DCOM- 20190204 LR - 20221207 IS - 1557-8518 (Electronic) IS - 1540-4196 (Linking) VI - 16 IP - 6 DP - 2018 Aug TI - Commentary on: "Effects of Regular Physical Activity on the Cognitive Performance of Type 2 Diabetic Patients: A Systematic Review" by Podolski et al. (Metab Syndr Relat Disord 2017;15:481-493). PG - 255-261 LID - 10.1089/met.2018.0021 [doi] AB - Type 2 diabetes mellitus (T2DM) imparts an increased risk for cognitive decline, specifically executive function, which is important to maintain for diabetes self-management. There is evidence to suggest that exercise improves cognition in healthy older adults; however, the literature in adults with T2DM is lacking. This commentary is in complement to Podolski et al.'s systematic review evaluating the effects of physical activity on cognitive function in adults with T2DM. We have included eight additional studies and further highlight their conclusions on the heterogeneity of the literature thus far. Three current issues with the literature are as follows: (1) variability in interventions (e.g., aerobic, resistance, lifestyle, and yoga), (2) variability in cognitive outcome measures, and (3) lack of detailed description of the population studied, for example, baseline glycated hemoglobin (A1C) values. Overall, making it difficult to compare these studies and draw final conclusions. Thus, the efficacy for exercise to improve cognition in adults with T2DM is not yet well understood. Potential ways to mitigate these limitations could be for future studies that (1) use robust methodology whenever possible, that is, randomized controlled trials, (2) to follow current guideline-derived exercise recommendations for adults with T2DM, and (3) utilize cognitive outcome measures that are consistent across studies. The hope is that these consistencies in turn will help to determine the efficacy of exercise on cognitive function in adults with T2DM and therefore, allow national organizations to develop recommendations and guidelines for healthcare practitioners to follow. FAU - Shellington, Erin M AU - Shellington EM AD - 1 Department of Kinesiology, Faculty of Health Sciences, Western University , London, Canada . FAU - Reichert, Sonja M AU - Reichert SM AD - 2 Centre for Studies in Family Medicine, Department of Family Medicine, Schulich School of Medicine and Dentistry, Western University , London, Canada . FAU - Petrella, Robert J AU - Petrella RJ AD - 2 Centre for Studies in Family Medicine, Department of Family Medicine, Schulich School of Medicine and Dentistry, Western University , London, Canada . LA - eng PT - Comment PT - Journal Article DEP - 20180516 PL - United States TA - Metab Syndr Relat Disord JT - Metabolic syndrome and related disorders JID - 101150318 RN - 0 (Glycated Hemoglobin A) SB - IM CON - Metab Syndr Relat Disord. 2017 Dec;15(10):481-493. PMID: 29160740 MH - Aged MH - Cognition MH - Cognitive Dysfunction MH - *Diabetes Mellitus, Type 2 MH - Exercise MH - *Glycated Hemoglobin MH - Humans OTO - NOTNLM OT - cognitive function OT - exercise OT - type 2 diabetes mellitus EDAT- 2018/05/17 06:00 MHDA- 2019/02/05 06:00 CRDT- 2018/05/17 06:00 PHST- 2018/05/17 06:00 [pubmed] PHST- 2019/02/05 06:00 [medline] PHST- 2018/05/17 06:00 [entrez] AID - 10.1089/met.2018.0021 [doi] PST - ppublish SO - Metab Syndr Relat Disord. 2018 Aug;16(6):255-261. doi: 10.1089/met.2018.0021. Epub 2018 May 16.