PMID- 29769503
OWN - NLM
STAT- MEDLINE
DCOM- 20190618
LR  - 20190618
IS  - 2408-8757 (Electronic)
IS  - 1022-4742 (Linking)
VI  - 27
IP  - 2
DP  - 2018 Apr
TI  - Vitamin D Status in Newly Diagnosed Type 2 Diabetes Patients Attending in a 
      Tertiary Hospital of Bangladesh.
PG  - 362-368
AB  - Vitamin D deficiency is common in patients with type 2 diabetes mellitus (T2DM). 
      Vitamin D status may have a causal role in the onset of T2DM and may influence 
      glycaemic control in these patients. However, data on vitamin D status among 
      Bangladeshi T2DM patients are scarce. The present cross-sectional study was done 
      among newly diagnosed 50 T2DM patients attending outpatient department of Comilla 
      Diabetic Hospital, Bangladesh to address this lacuna. Serum 25(OH)D was measured 
      in all and classified as normal (>/=30ng/mL), insufficient (>20 to 29.9ng/mL), and 
      deficient (</=20ng/mL). Mean serum 25(OH)D level was 27.91+/-2.58ng/mL (mean+/-SEM). 
      Among the study subjects, 30% were D-deficient, 36% were D-insufficient and 34% 
      had normal 25(OH)D. There was no statistical difference of 25(OH)D level between 
      the younger (age <40 years) and older (>/=40 years) patients (28.31+/-4.3 vs. 
      27.44+/-2.6ng/mL, mean+/-SEM; p=0.869); males and females (26.79+/-2.1 vs. 
      31.09+/-8.2ng/mL, mean+/-SEM; p=0.470); among smokers, non-smokers and ex-smokers 
      (26.86+/-4.31, 27.10+/-2.49 and 42.62+/-1.71ng/mL respectively, mean+/-SEM; p=0.363); 
      among normal weight, overweight and obese (30.61+/-6.16, 35.61+/-9.52 and 
      24.27+/-1.71ng/mL respectively, mean+/-SEM; p=0.191); and among normotensive, 
      borderline hypertensive and hypertensive (25.29+/-2.46, 32.57+/-5.32 and 
      20.84+/-3.66ng/mL respectively, mean+/-SEM; p=0.277) patients. 25(OH)D level showed 
      significant negative correlation with body mass index (r= -0.391, p=0.017) and 
      positive correlation (r=0.334, p=0.044) with fasting plasma glucose in male 
      subjects. Age, sex, smoking status, BMI, systolic BP, diastolic BP, family 
      history of DM and smoking status were not found to influence vitamin D level 
      independently. Our study found high frequency of subnormal vitamin D in newly 
      diagnosed T2DM patients. Screening for vitamin D status may be beneficial in T2DM 
      patients.
FAU - Alam, M S
AU  - Alam MS
AD  - Dr Muhammad Shah Alam, Senior Consultant, Comilla Diabetic Hospital, Comilla, 
      Bangladesh.
FAU - Kamrul-Hasan, M
AU  - Kamrul-Hasan M
FAU - Kalam, S T
AU  - Kalam ST
FAU - Selim, S
AU  - Selim S
FAU - Akter, F
AU  - Akter F
FAU - Saifuddin, M
AU  - Saifuddin M
LA  - eng
PT  - Journal Article
PL  - Bangladesh
TA  - Mymensingh Med J
JT  - Mymensingh medical journal : MMJ
JID - 9601799
RN  - 1406-16-2 (Vitamin D)
SB  - IM
MH  - Adult
MH  - Bangladesh
MH  - Cross-Sectional Studies
MH  - *Diabetes Mellitus, Type 2/complications
MH  - Female
MH  - Humans
MH  - Male
MH  - Tertiary Care Centers
MH  - Vitamin D
MH  - Vitamin D Deficiency/blood/complications
EDAT- 2018/05/18 06:00
MHDA- 2019/06/19 06:00
CRDT- 2018/05/18 06:00
PHST- 2018/05/18 06:00 [entrez]
PHST- 2018/05/18 06:00 [pubmed]
PHST- 2019/06/19 06:00 [medline]
PST - ppublish
SO  - Mymensingh Med J. 2018 Apr;27(2):362-368.