PMID- 29774220
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 2307-8960 (Print)
IS  - 2307-8960 (Electronic)
IS  - 2307-8960 (Linking)
VI  - 6
IP  - 5
DP  - 2018 May 16
TI  - Serum matrix metalloproteinase 3 in detecting remitting seronegative symmetrical 
      synovitis with pitting edema syndrome: A case report.
PG  - 84-87
LID - 10.12998/wjcc.v6.i5.84 [doi]
AB  - We report a case of remitting seronegative symmetrical synovitis with pitting 
      edema (RS3PE) syndrome in a 71-year-old woman. She referred to our hospital with 
      finger stiffness, edema of both hands and feet, pain of bilateral shoulder, 
      wrist, metacarpophalangeal, proximal interphalangeal, and ankle joints. 
      Rheumatoid factor was negative, human leukocyte antigen -B7 antigen was positive. 
      Moreover, matrix metalloproteinase 3 (MMP-3) was high. She was diagnosed with 
      RS3PE syndrome, and treatment with prednisolone (15 mg/d) was started. One week 
      after prednisolone treatment initiation, CRP decreased to negative, and joint 
      pain was almost completely resolved. However, hand stiffness persisted, and MMP-3 
      level was still high. Thus, prednisolone dose was increased to 20 mg/d, and the 
      stiffness resolved. Twenty days after treatment initiation, MMP-3 was normalized. 
      MMP-3 was more indicative of RS3PE syndrome symptoms than CRP. Thus, MMP-3 seems 
      to be more sensitive to RS3PE syndrome symptoms.
FAU - Kenzaka, Tsuneaki
AU  - Kenzaka T
AD  - Department of Internal Medicine, Hyogo Prefectural Kaibara Hospital, Hyogo 
      669-3395, Japan.
FAU - Goda, Ken
AU  - Goda K
AD  - Department of Internal Medicine, Hyogo Prefectural Kaibara Hospital, Hyogo 
      669-3395, Japan.
LA  - eng
PT  - Case Reports
PL  - United States
TA  - World J Clin Cases
JT  - World journal of clinical cases
JID - 101618806
PMC - PMC5955732
OTO - NOTNLM
OT  - Remitting seronegative symmetrical synovitis with pitting edema syndrome
OT  - Serum matrix metalloproteinase 3
COIS- Conflict-of-interest statement: The authors declare that they have no competing 
      interests.
EDAT- 2018/05/19 06:00
MHDA- 2018/05/19 06:01
PMCR- 2018/05/16
CRDT- 2018/05/19 06:00
PHST- 2017/12/22 00:00 [received]
PHST- 2018/02/15 00:00 [revised]
PHST- 2018/03/07 00:00 [accepted]
PHST- 2018/05/19 06:00 [entrez]
PHST- 2018/05/19 06:00 [pubmed]
PHST- 2018/05/19 06:01 [medline]
PHST- 2018/05/16 00:00 [pmc-release]
AID - 10.12998/wjcc.v6.i5.84 [doi]
PST - ppublish
SO  - World J Clin Cases. 2018 May 16;6(5):84-87. doi: 10.12998/wjcc.v6.i5.84.