PMID- 29775427
OWN - NLM
STAT- MEDLINE
DCOM- 20180917
LR  - 20180917
IS  - 1944-0057 (Electronic)
IS  - 1944-0057 (Linking)
VI  - 35
IP  - 8
DP  - 2018 Aug
TI  - Determination of fipronil and its metabolites in chicken egg, muscle and cake by 
      a modified QuEChERS method coupled with LC-MS/MS.
PG  - 1543-1552
LID - 10.1080/19440049.2018.1472395 [doi]
AB  - An easy-to-use method for determining the levels of fipronil and its metabolites 
      (fipronil-desulfinyl, fipronil-sulfone and fipronil-sulfide) in chicken egg, 
      muscle and cake was developed and validated using a modified quick, easy, cheap, 
      effective, rugged and safe (QuEChERS) approach coupled with liquid 
      chromatography-tandem mass spectrometry (LC-MS/MS) analysis. The samples were 
      extracted using acetonitrile, salted out with sodium chloride at -20 degrees C, and then 
      purified by combined PSA and C18 phases and anhydrous magnesium sulphate. The 
      recoveries were 80.4-119% with relative standard deviations (RSDs) < 10% for the 
      different matrixes. The validated method was used to analyse the target compounds 
      in 214 real samples collected in Beijing. The metabolite fipronil-sulfone was 
      detected in most of the samples and was identified as the main residue in the egg 
      and cake. The method was validated using a proficiency test for fipronil in 
      products of animal origin published by Wageningen University & Research in 2017.
FAU - Guo, Qiaozhen
AU  - Guo Q
AD  - a College of Science , Beijing University of Chemical Technology , Beijing , 
      China.
AD  - b Beijing Key Laboratory of Diagnostic and Traceability Technologies for Food 
      Poisoning , Beijing Center for Disease Control & Prevention , Beijing , China.
FAU - Zhao, Shan
AU  - Zhao S
AD  - b Beijing Key Laboratory of Diagnostic and Traceability Technologies for Food 
      Poisoning , Beijing Center for Disease Control & Prevention , Beijing , China.
FAU - Zhang, Jing
AU  - Zhang J
AD  - b Beijing Key Laboratory of Diagnostic and Traceability Technologies for Food 
      Poisoning , Beijing Center for Disease Control & Prevention , Beijing , China.
FAU - Qi, Kailun
AU  - Qi K
AD  - b Beijing Key Laboratory of Diagnostic and Traceability Technologies for Food 
      Poisoning , Beijing Center for Disease Control & Prevention , Beijing , China.
FAU - Du, Zhenxia
AU  - Du Z
AD  - a College of Science , Beijing University of Chemical Technology , Beijing , 
      China.
FAU - Shao, Bing
AU  - Shao B
AD  - b Beijing Key Laboratory of Diagnostic and Traceability Technologies for Food 
      Poisoning , Beijing Center for Disease Control & Prevention , Beijing , China.
AD  - c Beijing Advanced Innovation Center for Food Nutrition and Human Health , China 
      Agricultural University , Beijing , China.
LA  - eng
PT  - Journal Article
DEP - 20180619
PL  - England
TA  - Food Addit Contam Part A Chem Anal Control Expo Risk Assess
JT  - Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & 
      risk assessment
JID - 101485040
RN  - 0 (Insecticides)
RN  - 0 (Pyrazoles)
RN  - QGH063955F (fipronil)
SB  - IM
MH  - Animals
MH  - Chickens
MH  - Chromatography, Liquid
MH  - Food Contamination/*analysis
MH  - Insecticides/*analysis/metabolism
MH  - Muscles/*chemistry
MH  - Ovum/*chemistry
MH  - Pyrazoles/*analysis/metabolism
MH  - Tandem Mass Spectrometry
OTO - NOTNLM
OT  - Fipronil and its metabolites
OT  - cake
OT  - chicken egg
OT  - muscle
OT  - ultra-performance liquid chromatography-tandem mass spectrometry
EDAT- 2018/05/19 06:00
MHDA- 2018/09/18 06:00
CRDT- 2018/05/19 06:00
PHST- 2018/05/19 06:00 [pubmed]
PHST- 2018/09/18 06:00 [medline]
PHST- 2018/05/19 06:00 [entrez]
AID - 10.1080/19440049.2018.1472395 [doi]
PST - ppublish
SO  - Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2018 
      Aug;35(8):1543-1552. doi: 10.1080/19440049.2018.1472395. Epub 2018 Jun 19.