PMID- 29777494
OWN - NLM
STAT- MEDLINE
DCOM- 20190102
LR  - 20210130
IS  - 1614-7499 (Electronic)
IS  - 0944-1344 (Linking)
VI  - 25
IP  - 21
DP  - 2018 Jul
TI  - Residue behavior and risk assessment of thifluzamide in the maize field 
      ecosystem.
PG  - 21195-21204
LID - 10.1007/s11356-018-2211-z [doi]
AB  - In the present work, the dissipation kinetics and final residue levels of 
      thifluzamide in the maize field ecosystem were investigated. Using a modified 
      quick, easy, cheap, effective, rugged, and safe (QuEChERS) extraction combined 
      with liquid chromatography-tandem mass spectrometric detection (LC-MS/MS), a 
      rapid, sensitive, efficient, and reliable method for extraction and quantitative 
      analysis of thifluzamide residues in maize grain, maize plant, and soil was 
      developed. Satisfactory recoveries of 78.7-97.0% were achieved with relative 
      standard deviations (RSDs) in the range of 1.6 to 8.2%. The limits of detection 
      (LODs) and the limit of quantification (LOQ) were 0.002-0.005 and 
      0.010 mg kg(-1), respectively. The dissipation kinetics of thifluzamide in maize 
      plant was well fitted by the first-order kinetic model with short half-lives of 
      0.19-0.22 days, while thifluzamide degraded slowly in soil with half-lives of 
      4.56-15.85 days. The final residues in maize grain, maize plant, and soil samples 
      collected at the milk stage and the physiological maturity stage were no more 
      than 0.010, 0.807, and 0.278 mg kg(-1), respectively. Given that no maximum 
      residue limit (MRL) for thifluzamide in maize has been established, the safety of 
      this fungicide application was estimated by a dietary risk assessment. The 
      hazard quotient was 0.03%, which was substantially less than 1, indicating that 
      the long-term risk induced by the thifluzamide application on maize at the 
      recommended dose is negligible. These results help governments to develop 
      regulations for the safe use of thifluzamide.
FAU - Ma, Cong
AU  - Ma C
AD  - Food Science and Technology, Grain College, Henan University of Technology, 
      Zhengzhou, 450052, People's Republic of China.
AD  - Institute of Quality Standards and Testing Technology for Agro-Products, Chinese 
      Academy of Agricultural Sciences, Beijing, 100081, People's Republic of China.
FAU - Liu, Zhongdong
AU  - Liu Z
AD  - Food Science and Technology, Grain College, Henan University of Technology, 
      Zhengzhou, 450052, People's Republic of China. liuzhongdong2345@163.com.
FAU - Qi, Yan
AU  - Qi Y
AD  - Institute of Quality Standards and Testing Technology for Agro-Products, Chinese 
      Academy of Agricultural Sciences, Beijing, 100081, People's Republic of China.
FAU - Wang, Shanshan
AU  - Wang S
AUID- ORCID: 0000-0002-9289-8174
AD  - Institute of Quality Standards and Testing Technology for Agro-Products, Chinese 
      Academy of Agricultural Sciences, Beijing, 100081, People's Republic of China. 
      wangshanshan@caas.cn.
FAU - Cao, Xiaolin
AU  - Cao X
AD  - Institute of Quality Standards and Testing Technology for Agro-Products, Chinese 
      Academy of Agricultural Sciences, Beijing, 100081, People's Republic of China.
FAU - Wang, Jing
AU  - Wang J
AD  - Institute of Quality Standards and Testing Technology for Agro-Products, Chinese 
      Academy of Agricultural Sciences, Beijing, 100081, People's Republic of China. 
      w_jing2001@126.com.
FAU - She, Yongxin
AU  - She Y
AD  - Institute of Quality Standards and Testing Technology for Agro-Products, Chinese 
      Academy of Agricultural Sciences, Beijing, 100081, People's Republic of China.
FAU - Shao, Yong
AU  - Shao Y
AD  - Institute of Quality Standards and Testing Technology for Agro-Products, Chinese 
      Academy of Agricultural Sciences, Beijing, 100081, People's Republic of China.
FAU - Shen, Jitai
AU  - Shen J
AD  - Institute of Quality Standards and Testing Technology for Agro-Products, Chinese 
      Academy of Agricultural Sciences, Beijing, 100081, People's Republic of China.
FAU - Zhang, Chao
AU  - Zhang C
AD  - Institute of Quality Standards and Testing Technology for Agro-Products, Chinese 
      Academy of Agricultural Sciences, Beijing, 100081, People's Republic of China.
FAU - Jiang, Zejun
AU  - Jiang Z
AD  - Institute of Quality Standards and Testing Technology for Agro-Products, Chinese 
      Academy of Agricultural Sciences, Beijing, 100081, People's Republic of China.
LA  - eng
GR  - 31401590/National Natural Science Foundation of China/
GR  - 2016YFD0400800/National Key R&D Program of China/
GR  - 1610072017007/Central Public-interest Scientific Institution Basal Research Fund/
PT  - Evaluation Study
PT  - Journal Article
DEP - 20180518
PL  - Germany
TA  - Environ Sci Pollut Res Int
JT  - Environmental science and pollution research international
JID - 9441769
RN  - 0 (Anilides)
RN  - 0 (Pesticide Residues)
RN  - 0 (Soil)
RN  - 0 (Soil Pollutants)
RN  - 0 (Thiazoles)
RN  - 2J3TB6Z254 (thifluzamide)
SB  - IM
MH  - Anilides/*chemistry
MH  - Chromatography, Liquid/*methods
MH  - Ecosystem
MH  - Half-Life
MH  - Kinetics
MH  - Limit of Detection
MH  - Pesticide Residues/*chemistry
MH  - Soil/chemistry
MH  - Soil Pollutants/*chemistry
MH  - Tandem Mass Spectrometry/*methods
MH  - Thiazoles/*chemistry
MH  - Zea mays/chemistry/*growth & development
OTO - NOTNLM
OT  - Dissipation behavior
OT  - Final residues
OT  - LC-MS/MS
OT  - Maize
OT  - Modified QuEChERS extraction
OT  - Risk assessment
OT  - Thifluzamide
EDAT- 2018/05/20 06:00
MHDA- 2019/01/03 06:00
CRDT- 2018/05/20 06:00
PHST- 2018/01/08 00:00 [received]
PHST- 2018/05/01 00:00 [accepted]
PHST- 2018/05/20 06:00 [pubmed]
PHST- 2019/01/03 06:00 [medline]
PHST- 2018/05/20 06:00 [entrez]
AID - 10.1007/s11356-018-2211-z [pii]
AID - 10.1007/s11356-018-2211-z [doi]
PST - ppublish
SO  - Environ Sci Pollut Res Int. 2018 Jul;25(21):21195-21204. doi: 
      10.1007/s11356-018-2211-z. Epub 2018 May 18.