PMID- 29788503
OWN - NLM
STAT- MEDLINE
DCOM- 20200422
LR  - 20200422
IS  - 1460-2393 (Electronic)
IS  - 1460-2393 (Linking)
VI  - 111
IP  - 8
DP  - 2018 Aug 1
TI  - Visual analogue scales for interstitial lung disease: a prospective validation 
      study.
PG  - 531-539
LID - 10.1093/qjmed/hcy102 [doi]
AB  - BACKGROUND: Visual analogue scales (VAS) are simple symptom assessment tools 
      which have not been validated in interstitial lung disease (ILD). Simple measures 
      of ILD disease burden would be valuable for non-specialist clinicians monitoring 
      disease away from ILD specialist centres. OBJECTIVE: To validate VAS to assess 
      change in dyspnoea, cough and fatigue in ILD, and to define the minimal 
      clinically important difference (MCID) for change in these. METHODS: Patients of 
      64 with ILD completed VAS for dyspnoea, cough and fatigue. Baseline King's Brief 
      ILD questionnaire (K-BILD) scores, lung function and 6-min walk test results were 
      collected. Tests were repeated 3-6 months later, in addition to a seven-point 
      Likert scale. The MCID was estimated using median change in VAS in patients who 
      reported 'small but just worthwhile change' in symptoms at follow-up. Methods 
      were repeated in a validation cohort of 31 ILD patients to confirm findings. 
      RESULTS: VAS scores were significantly higher for patients who reported a 'small 
      but just worthwhile change' in symptoms vs. 'no change' or 'not worthwhile 
      change' (P < 0.01). The MCID for VAS Dyspnoea was estimated as 22.0 mm and 
      14.5 mm for VAS Fatigue. These results were reproducible in the validation 
      cohort. Results were not significant for VAS Cough. Change in VAS Dyspnoea 
      correlated with change in K-BILD (r = -0.51, P < 0.01), forced vital capacity (r 
      = -0.32, P = 0.01) and 6-min walking distance (r = -0.37, P = 0.01). CONCLUSION: 
      The VAS is valid for assessing change in dyspnoea and fatigue in ILD. The MCID is 
      estimated as 22.0 mm for dyspnoea and 14.5 mm for fatigue. This could be used to 
      monitor disease in settings away from ILD specialist review. MESH DESCRIPTORS: 
      Lung Diseases, Interstitial, Dyspnoea, Fatigue, Cough.
CI  - (c) The Author(s) 2018. Published by Oxford University Press on behalf of the 
      Association of Physicians. All rights reserved. For permissions, please email: 
      journals.permissions@oup.com.
FAU - Yates, H
AU  - Yates H
AD  - Respiratory and Sleep Physiology, Royal Brompton and Harefield NHS Trust, London, 
      UK.
FAU - Adamali, H I
AU  - Adamali HI
AD  - Bristol ILD Service, North Bristol NHS Trust, Bristol, UK.
FAU - Maskell, N
AU  - Maskell N
AD  - Academic Respiratory Unit, University of Bristol, Southmead Hospital, Bristol, 
      UK.
FAU - Barratt, S
AU  - Barratt S
AD  - Bristol ILD Service, North Bristol NHS Trust, Bristol, UK.
FAU - Sharp, C
AU  - Sharp C
AD  - Respiratory Department, Gloucestershire Hospitals NHS Foundation Trust, 
      Gloucester Royal Hospital, Great Western Road, Gloucester, UK.
LA  - eng
PT  - Journal Article
PT  - Observational Study
PT  - Validation Study
PL  - England
TA  - QJM
JT  - QJM : monthly journal of the Association of Physicians
JID - 9438285
SB  - IM
MH  - Aged
MH  - Cough/etiology/*physiopathology/psychology
MH  - Dyspnea/etiology/*physiopathology/psychology
MH  - Fatigue/etiology/*physiopathology/psychology
MH  - Female
MH  - Humans
MH  - Lung Diseases, Interstitial/complications/*physiopathology/psychology
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - Severity of Illness Index
MH  - Surveys and Questionnaires
MH  - Visual Analog Scale
MH  - Vital Capacity/physiology
EDAT- 2018/05/23 06:00
MHDA- 2020/04/23 06:00
CRDT- 2018/05/23 06:00
PHST- 2018/03/10 00:00 [received]
PHST- 2018/04/25 00:00 [revised]
PHST- 2018/05/23 06:00 [pubmed]
PHST- 2020/04/23 06:00 [medline]
PHST- 2018/05/23 06:00 [entrez]
AID - 4996822 [pii]
AID - 10.1093/qjmed/hcy102 [doi]
PST - ppublish
SO  - QJM. 2018 Aug 1;111(8):531-539. doi: 10.1093/qjmed/hcy102.