PMID- 29796031 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200930 IS - 1735-0328 (Print) IS - 1726-6890 (Electronic) IS - 1726-6882 (Linking) VI - 17 IP - Suppl DP - 2018 Winter TI - Vitamin D Deficiency Predicts the ST Elevation Type of Myocardial Infarction in Patients with Acute Coronary Syndrome. PG - 73-78 AB - According to studies, a significant association exists between the low levels of vitamin D and cardiovascular diseases such as myocardial infarction (MI). In a prospective case control study, 88 patients with acute coronary syndrome (ACS) including ST elevation myocardial infarction (STEMI) and Non-STEMI were enrolled. The plasma level of 25-hydroxy vitamin D [25(OH) D] was obtained at the time of acute MI. To assess the association between study variables logistic regression analysis was done. The overall rate of vitamin D deficiency was documented in 59.1% with the significantly higher prevalence rate in STEMI group (77.5% versus 43.7%; p = 0.001). In STEMI group, the plasma level of 25(OH) vitamin D was significantly lower than non-STEMI group (13.5 +/- 7.7 versus 24.3 +/- 14.9; p = 0.001). Vitamin D deficiency was the main predictor in occurring the ST elevation type of MI (Odd ratio: 8.1, 95% CI: 2.3 - 28.2; p = 0.001). The results of the present study demonstrated a higher prevalence of vitamin D deficiency among ACS patients. Furthermore, vitamin D deficiency was responsible for occurring ST elevation type of MI among ACS patients. Large studies are needed to confirm these findings. FAU - Safaie, Naser AU - Safaie N AD - Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. FAU - Rezaee, Haleh AU - Rezaee H AD - Department of Clinical Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran. FAU - Seif Dvati, Babak AU - Seif Dvati B AD - Department of Clinical Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran. FAU - Entezari-Maleki, Taher AU - Entezari-Maleki T AD - Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. AD - Department of Clinical Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran. LA - eng PT - Journal Article PL - Netherlands TA - Iran J Pharm Res JT - Iranian journal of pharmaceutical research : IJPR JID - 101208407 PMC - PMC5958326 OTO - NOTNLM OT - Acute coronary syndrome OT - Myocardial infarction OT - Non-STEMI OT - STEMI OT - Vitamin D deficiency EDAT- 2018/05/26 06:00 MHDA- 2018/05/26 06:01 PMCR- 2018/01/01 CRDT- 2018/05/26 06:00 PHST- 2018/05/26 06:00 [entrez] PHST- 2018/05/26 06:00 [pubmed] PHST- 2018/05/26 06:01 [medline] PHST- 2018/01/01 00:00 [pmc-release] AID - ijpr-17-073 [pii] PST - ppublish SO - Iran J Pharm Res. 2018 Winter;17(Suppl):73-78.