PMID- 2979632 OWN - NLM STAT- MEDLINE DCOM- 19920207 LR - 20170214 IS - 0748-7304 (Print) IS - 0748-7304 (Linking) VI - 3 IP - 1 DP - 1988 Spring TI - Axon-sparing lesions of the hypothalamic paraventricular nucleus abolish gonadal responses to photoperiod in male Syrian hamsters. PG - 59-69 AB - Intrahypothalamic injections of the excitotoxin N-methyl-D,L-aspartic acid (NMA) that destroyed the parvocellular regions of the paraventricular nucleus (PVN) prevented gonadal regression in male hamsters (Mesocricetus auratus) kept in short days (LD 6:18). After 17 weeks in short days, these NMA-injected animals had large, functional gonads and displayed all components of male sexual behavior. These findings confirm that neurons of the PVN are part of the pathway that mediates photoperiodism in hamsters. FAU - Brown, M H AU - Brown MH AD - Department of Psychology and Neuroscience, Michigan State University, East Lansing 48824-1117. FAU - Badura, L L AU - Badura LL FAU - Nunez, A A AU - Nunez AA LA - eng GR - MH 37877/MH/NIMH NIH HHS/United States PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, P.H.S. PL - United States TA - J Biol Rhythms JT - Journal of biological rhythms JID - 8700115 RN - 6384-92-5 (N-Methylaspartate) SB - IM MH - Animals MH - Axons/*physiology MH - Cricetinae MH - *Light MH - Male MH - Mesocricetus MH - N-Methylaspartate/pharmacology MH - Paraventricular Hypothalamic Nucleus/drug effects/*physiology MH - *Periodicity MH - Testis/*physiology EDAT- 1988/01/01 00:00 MHDA- 1988/01/01 00:01 CRDT- 1988/01/01 00:00 PHST- 1988/01/01 00:00 [pubmed] PHST- 1988/01/01 00:01 [medline] PHST- 1988/01/01 00:00 [entrez] AID - 10.1177/074873048800300105 [doi] PST - ppublish SO - J Biol Rhythms. 1988 Spring;3(1):59-69. doi: 10.1177/074873048800300105.