PMID- 29804405
OWN - NLM
STAT- MEDLINE
DCOM- 20181211
LR  - 20181211
IS  - 0376-2491 (Print)
IS  - 0376-2491 (Linking)
VI  - 98
IP  - 18
DP  - 2018 May 15
TI  - [Clinical manifestations analysis of patients diagnosed with primary pulmonary 
      mucosa-associated lymphoid tissue lymphoma].
PG  - 1419-1423
LID - 10.3760/cma.j.issn.0376-2491.2018.18.010 [doi]
AB  - Objective: To analyze the clinical features of pulmonary mucosa-associated 
      lymphoid tissue (MALT) lymphoma. Methods: A total of 14 cases diagnosed with 
      primary pulmonary MALT lymphoma were collected from May 2007 to May 2017 in 
      Zhongshan Hospital, Fudan University. The clinical features, pathological 
      characteristics, diagnosis, treatment and prognosis were retrospectively 
      analyzed. Results: All 14 cases were pathologically diagnosed with primary 
      pulmonary MALT lymphoma. The biopsy tissues were obtained through the 
      Video-assisted Thoracoscopic Surgery (VATS) (4 cases), percutaneous puncture (2 
      cases), and bronchoscopy (8 cases). Cell types of these tumors were 
      centrocyte-like cells (10 cases), lymphocytoid cells (2 cases), and monocytoid B 
      cells (2 cases). The B cell clonality was detected by IgH cloning test in 4 cases 
      and 3 of them were demonstrated with monoclonal strips. MALT1 breakup gene was 
      positive in 3 out of 6 examined cases using fluorescence in situ hybridization 
      (FISH). As for the treatment, 8 patients underwent chemotherapy, 5 patients 
      underwent surgical resection and 1 patient abandoned treatment. Twelve patients 
      were followed up to 9 years. The tumor recurrence occurred in 2 patients and 
      resulted their death. Conclusions: The clinical manifestations of primary 
      pulmonary MALT lymphoma are lack of specificity. The pathology, 
      immunohistochemistry, IgH cloning test and MALT1 breakup gene tested by FISH are 
      the criteria for diagnosis.
FAU - Bao, C
AU  - Bao C
AD  - Respiratory Department, Zhongshan Hospital, Fudan University, Shanghai 200032, 
      China.
FAU - Wang, X C
AU  - Wang XC
FAU - Hu, X L
AU  - Hu XL
FAU - Hou, D N
AU  - Hou DN
FAU - Chen, C C
AU  - Chen CC
FAU - Song, Y L
AU  - Song YL
FAU - Yang, D
AU  - Yang D
LA  - chi
PT  - Journal Article
PL  - China
TA  - Zhonghua Yi Xue Za Zhi
JT  - Zhonghua yi xue za zhi
JID - 7511141
SB  - IM
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - *Lymphoma, B-Cell, Marginal Zone
MH  - Neoplasm Recurrence, Local
MH  - Retrospective Studies
MH  - Translocation, Genetic
OTO - NOTNLM
OT  - Diagnosis
OT  - Lymphoma, B-cell, marginal zone
OT  - Pathology
OT  - Treatment
EDAT- 2018/05/29 06:00
MHDA- 2018/12/12 06:00
CRDT- 2018/05/28 06:00
PHST- 2018/05/28 06:00 [entrez]
PHST- 2018/05/29 06:00 [pubmed]
PHST- 2018/12/12 06:00 [medline]
AID - 10.3760/cma.j.issn.0376-2491.2018.18.010 [doi]
PST - ppublish
SO  - Zhonghua Yi Xue Za Zhi. 2018 May 15;98(18):1419-1423. doi: 
      10.3760/cma.j.issn.0376-2491.2018.18.010.