PMID- 29804925
OWN - NLM
STAT- MEDLINE
DCOM- 20190520
LR  - 20191210
IS  - 1573-2509 (Electronic)
IS  - 0920-9964 (Linking)
VI  - 201
DP  - 2018 Nov
TI  - Factor structure of the positive and negative syndrome scale (PANSS) in people at 
      ultra high risk (UHR) for psychosis.
PG  - 85-90
LID - S0920-9964(18)30281-0 [pii]
LID - 10.1016/j.schres.2018.05.024 [doi]
AB  - INTRODUCTION: The Positive and Negative Syndrome Scale (PANSS), a comprehensive 
      psychopathology assessment scale used in the evaluation of psychopathology in 
      schizophrenia, is also often used in the Ultra-High-Risk (UHR) population. This 
      paper examined the dimensional structure of the PANSS in a UHR sample. METHODS: A 
      total of 168 individuals assessed to be at UHR for psychosis on the Comprehensive 
      Assessment of At-Risk Mental States (CAARMS) were evaluated on the PANSS, Calgary 
      Depression Scale for Schizophrenia (CDSS), Beck Anxiety Inventory (BAI), Brief 
      Assessment of Cognition in Schizophrenia (BACS), and Global Assessment of 
      Functioning (GAF). Exploratory factor analysis (EFA) of the PANSS was performed 
      to identify the factorial structure. Convergent validity was explored with the 
      CAARMS, CDSS, BAI and BACS. RESULTS: EFA of the PANSS yielded five symptom 
      factors - Positive, Negative, Cognition/Disorganization, Anxiety/Depression, and 
      Hostility. This 5-factor solution showed good convergent validity with the CAARMS 
      composite score, CDSS, BAI, and BACS. Positive, Negative and Anxiety/Depression 
      factors were associated with functioning. CONCLUSION: The reported PANSS factor 
      structure may serve to improve the understanding and measurement of clinical 
      symptom dimensions manifested in people with UHR for future research and clinical 
      setting.
CI  - Copyright (c) 2018 Elsevier B.V. All rights reserved.
FAU - Yang, Zixu
AU  - Yang Z
AD  - Research Division, Institute of Mental Health, Singapore, Singapore.
FAU - Lim, Keane
AU  - Lim K
AD  - Research Division, Institute of Mental Health, Singapore, Singapore.
FAU - Lam, Max
AU  - Lam M
AD  - Research Division, Institute of Mental Health, Singapore, Singapore.
FAU - Keefe, Richard
AU  - Keefe R
AD  - Department of Psychiatry & Behavioral Sciences, Duke University Medical Center, 
      Durham, USA.
FAU - Lee, Jimmy
AU  - Lee J
AD  - Research Division, Institute of Mental Health, Singapore, Singapore; Department 
      of Psychosis, Institute of Mental Health, Singapore, Singapore; Lee Kong Chian 
      School of Medicine, Nanyang Technological University, Singapore, Singapore. 
      Electronic address: jimmy_lee@imh.com.sg.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Validation Study
DEP - 20180524
PL  - Netherlands
TA  - Schizophr Res
JT  - Schizophrenia research
JID - 8804207
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Factor Analysis, Statistical
MH  - Female
MH  - Humans
MH  - Longitudinal Studies
MH  - Male
MH  - *Psychiatric Status Rating Scales
MH  - Psychotic Disorders/*diagnosis
MH  - Risk
MH  - Young Adult
OTO - NOTNLM
OT  - Factor
OT  - Functioning
OT  - PANSS
OT  - UHR
OT  - Validity
EDAT- 2018/05/29 06:00
MHDA- 2019/05/21 06:00
CRDT- 2018/05/29 06:00
PHST- 2017/10/31 00:00 [received]
PHST- 2018/03/29 00:00 [revised]
PHST- 2018/05/13 00:00 [accepted]
PHST- 2018/05/29 06:00 [pubmed]
PHST- 2019/05/21 06:00 [medline]
PHST- 2018/05/29 06:00 [entrez]
AID - S0920-9964(18)30281-0 [pii]
AID - 10.1016/j.schres.2018.05.024 [doi]
PST - ppublish
SO  - Schizophr Res. 2018 Nov;201:85-90. doi: 10.1016/j.schres.2018.05.024. Epub 2018 
      May 24.