PMID- 29807344
OWN - NLM
STAT- MEDLINE
DCOM- 20180822
LR  - 20191210
IS  - 1879-1298 (Electronic)
IS  - 0045-6535 (Linking)
VI  - 207
DP  - 2018 Sep
TI  - Degradation of triclosan by chlorine dioxide: Reaction 
      mechanism,2,4-dichlorophenol accumulation and toxicity evaluation.
PG  - 449-456
LID - S0045-6535(18)30914-7 [pii]
LID - 10.1016/j.chemosphere.2018.05.065 [doi]
AB  - The mechanism and toxicity of TCS degradation by ClO(2) was investigated. 
      Intermediate products during the oxidation process were identified by GC/MS and 
      LC/MS. A microtox bioassay and a SOS/umu assay were employed to evaluate the 
      acute toxicity and genotoxicity of the resulting solutions during the 
      chlorination process. The results showed that the reaction between TCS and ClO(2) 
      was of second-order overall. The pseudo first-order rate constants (k(obs)) 
      exhibited significant dependence on solution pH and chlorine dioxide 
      concentration, with the apparent second-order rate constant, k(app), being 
      7.07 x 10(4) M(-1)s(-1) in the pH range of 6.80-7.02. TCS decomposition was 
      accompanied by the accumulation of 2,4-dichlorophenol (2,4-DCP), and the maximum 
      molar yield ratios of 2,4-DCP/TCS were in the range of 31.71%-35.43%. The major 
      intermediates identified were 2,7/2,8-dichlorodibenzop-dioxin (2,7/2.8-Cl(2)DD), 
      2,4-DCP, 2,4,6-trichlorophenol (2,4,6-TCP), tetraclosan and pentaclosan. The 
      proposed mechanism for TCS oxidation involved the cleavage of the ether link in 
      TCS, chlorination of the phenolic ring and ring closure of a single TCS molecule. 
      The transformation and degradation of TCS led to reduction of the acute toxicity 
      and genotoxicity. However, irregular fluctuations in the toxicity changes 
      indicated that the oxidation of TCS was not a simultaneous detoxification 
      process.
CI  - Copyright (c) 2018 Elsevier Ltd. All rights reserved.
FAU - Li, Qingsong
AU  - Li Q
AD  - Water Resources and Environmental Institute, Xiamen University of Technology, 
      Xiamen, 361005, China. Electronic address: leetsingsong@sina.com.
FAU - Yu, Jianwei
AU  - Yu J
AD  - Key Laboratory of Drinking Water Science and Technology, Research Center for 
      Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; 
      University of the Chinese Academy of Sciences, Beijing, 100019, China. Electronic 
      address: jwyu@rcees.ac.cn.
FAU - Chen, Weizhu
AU  - Chen W
AD  - Third Institute of Oceanography, State Oceanic Administration, People Republic of 
      China, Xiamen, 361005, China. Electronic address: chen1050@gmail.com.
FAU - Ma, Xiaoyan
AU  - Ma X
AD  - College of Civil Engineering and Architecture, Zhejiang University of Technology, 
      Hangzhou, 310014, China. Electronic address: mayaner620@sohu.com.
FAU - Li, Guoxin
AU  - Li G
AD  - Water Resources and Environmental Institute, Xiamen University of Technology, 
      Xiamen, 361005, China. Electronic address: 2011111701@xmut.edu.cn.
FAU - Chen, Guoyuan
AU  - Chen G
AD  - Water Resources and Environmental Institute, Xiamen University of Technology, 
      Xiamen, 361005, China. Electronic address: chengy@xmut.edu.cn.
FAU - Deng, Jing
AU  - Deng J
AD  - College of Civil Engineering and Architecture, Zhejiang University of Technology, 
      Hangzhou, 310014, China. Electronic address: zjut_djing@163.com.
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
DEP - 20180514
PL  - England
TA  - Chemosphere
JT  - Chemosphere
JID - 0320657
RN  - 0 (Chlorine Compounds)
RN  - 0 (Chlorophenols)
RN  - 0 (Oxides)
RN  - 0 (Water Pollutants, Chemical)
RN  - 4NM5039Y5X (Triclosan)
RN  - 8061YMS4RM (chlorine dioxide)
RN  - R669TG1950 (2,4-dichlorophenol)
SB  - IM
MH  - Aliivibrio fischeri/*drug effects/genetics
MH  - Chlorine Compounds/*chemistry
MH  - Chlorophenols/metabolism/*toxicity
MH  - Halogenation
MH  - Oxidation-Reduction
MH  - Oxides/*chemistry
MH  - Salmonella typhimurium/*drug effects/genetics
MH  - Toxicity Tests, Acute/*methods
MH  - Triclosan/*chemistry
MH  - Water Pollutants, Chemical/analysis
OTO - NOTNLM
OT  - Chlorine dioxide
OT  - Degradation intermediates
OT  - Toxicity
OT  - Triclosan
EDAT- 2018/05/29 06:00
MHDA- 2018/08/23 06:00
CRDT- 2018/05/29 06:00
PHST- 2018/01/03 00:00 [received]
PHST- 2018/05/10 00:00 [revised]
PHST- 2018/05/12 00:00 [accepted]
PHST- 2018/05/29 06:00 [pubmed]
PHST- 2018/08/23 06:00 [medline]
PHST- 2018/05/29 06:00 [entrez]
AID - S0045-6535(18)30914-7 [pii]
AID - 10.1016/j.chemosphere.2018.05.065 [doi]
PST - ppublish
SO  - Chemosphere. 2018 Sep;207:449-456. doi: 10.1016/j.chemosphere.2018.05.065. Epub 
      2018 May 14.