PMID- 29809362
OWN - NLM
STAT- MEDLINE
DCOM- 20180628
LR  - 20191113
IS  - 0015-5497 (Print)
IS  - 0015-5497 (Linking)
VI  - 64
IP  - 4
DP  - 2016
TI  - Hematological Alterations as a Response to Exposure to Selected Fungicides in 
      Common Carp (Cyprinus carpio L.).
PG  - 235-244
AB  - The aim of the present study was to assess the hematological response of common 
      carp to fungicides and to determine recovery patterns in fungicide-free water. 
      Fish were exposed to mancozeb, prochloraz or tebuconazole (at concentrations of 
      1.0, 1.0 and 2.5 mg 1(-)(1), respectively) for 14 days followed by a 30-day recovery 
      period. The following hematological parameters were examined after 1, 3 and 14 
      days of exposure as well as after recovery time: red blood cells (RBC), 
      hematocrit (Het), total hemoglobin concentration (Hb), mean corpuscular volume 
      (MCV), mean corpuscular hemoglobin concentration (MCHC), mean corpuscular 
      hemoglobin (MCH), total number of leukocytes (WBC) and leukograms. All analyzed 
      parameters revealed alterations in relation to control samples. The pattern of 
      these changes was irregular, showing either an increase or decrease at different 
      time points of the experiment and not all observed differences were statistically 
      significant. The most noticeable fungicide-specific changes were,observed on the 
      1st and 14th days of chemical exposure. The majority of the parameters under 
      investigation returned to the control levels after a detoxication period. 
      However, some of the exerted effects were irreversible (Hb, MCH, MCHC and WBC for 
      fish subjected to mancozeb; Hb, MCH, MCHC and monocyte count for fish subjected 
      to prochloraz; Hct and monocyte number for fish subjected to tebuconazole). All 
      of the observed hematoloaical changes were not toxin-soecific.
FAU - Lutnicka, Hanna
AU  - Lutnicka H
FAU - Bojarski, Bartosz
AU  - Bojarski B
FAU - Ludwikowska, Agnieszka
AU  - Ludwikowska A
FAU - Wronska, Danuta
AU  - Wronska D
FAU - Kaminska, Teresa
AU  - Kaminska T
FAU - Szczygiel, Joanna
AU  - Szczygiel J
FAU - Troszok, Agnieszka
AU  - Troszok A
FAU - Szambelan, Katarzyna
AU  - Szambelan K
FAU - Formicki, Grzegorz
AU  - Formicki G
LA  - eng
PT  - Journal Article
PL  - Poland
TA  - Folia Biol (Krakow)
JT  - Folia biologica
JID - 2984758R
RN  - 0 (Fungicides, Industrial)
RN  - 0 (Hemoglobins)
RN  - 0 (Water Pollutants, Chemical)
SB  - IM
MH  - Animals
MH  - Carps/*blood
MH  - Erythrocyte Count/veterinary
MH  - Fish Diseases/blood/*chemically induced
MH  - Fungicides, Industrial/*toxicity
MH  - Hematocrit/veterinary
MH  - Hemoglobins/metabolism
MH  - Leukocyte Count/veterinary
MH  - Water Pollutants, Chemical/*toxicity
EDAT- 2016/01/01 00:00
MHDA- 2016/01/01 00:01
CRDT- 2018/05/30 06:00
PHST- 2018/05/30 06:00 [entrez]
PHST- 2016/01/01 00:00 [pubmed]
PHST- 2016/01/01 00:01 [medline]
AID - 10.3409/fb64_4.235 [doi]
PST - ppublish
SO  - Folia Biol (Krakow). 2016;64(4):235-244. doi: 10.3409/fb64_4.235.