PMID- 29842831
OWN - NLM
STAT- MEDLINE
DCOM- 20180905
LR  - 20180905
IS  - 1536-7290 (Electronic)
IS  - 1536-7290 (Linking)
VI  - 18
IP  - 8
DP  - 2018 Sep
TI  - Response of brain-derived neurotrophic factor to combining cognitive and physical 
      exercise.
PG  - 1119-1127
LID - 10.1080/17461391.2018.1470676 [doi]
AB  - PURPOSE: Brain-derived neurotrophic factor (BDNF) is well known for its potential 
      to promote brain plasticity. It has been proposed that combining cognitive and 
      physical exercise (CCPE) may have the potential to generate more synergistic 
      benefits in cognitive function than either cognitive exercise (CE) or physical 
      exercise (PE) alone. The purpose of this study was to examine acute responses of 
      peripheral BDNF levels and cognitive performance to CE, PE, and CCPE. METHODS: 
      Thirteen healthy adult men participated in four experimental sessions; a 30-min 
      CE, a 30-min cycling PE at an intensity of 60% peak oxygen uptake, a 30-min CCPE 
      at the same intensity as PE, and a 30-min session of complete rest. Plasma BDNF 
      levels and cognitive performance were measured before and after each session. 
      RESULTS: Both PE and CCPE significantly increased plasma BDNF levels (p < .05). 
      CE led to no significant increase (p >/= .05), and there was no significant 
      difference in peripheral BDNF levels between PE and CCPE (p >/= .05). No session 
      induced a significant change in cognitive performance (p >/= .05). CONCLUSIONS: Our 
      study suggests that CE and PE have different responses of peripheral BDNF levels 
      and that CCPE had no additional or synergistic effect on peripheral BDNF levels 
      compared with PE alone. This study offers further insights into the potential 
      mechanisms underlying the respective roles of CE, PE, and CCPE for peripheral 
      BDNF levels and cognitive performance.
FAU - Miyamoto, Toshiaki
AU  - Miyamoto T
AD  - a Department of Physical Therapy, School of Rehabilitation , Hyogo University of 
      Health Sciences , Kobe , Japan.
FAU - Hashimoto, Saya
AU  - Hashimoto S
AD  - a Department of Physical Therapy, School of Rehabilitation , Hyogo University of 
      Health Sciences , Kobe , Japan.
FAU - Yanamoto, Hideya
AU  - Yanamoto H
AD  - a Department of Physical Therapy, School of Rehabilitation , Hyogo University of 
      Health Sciences , Kobe , Japan.
FAU - Ikawa, Mai
AU  - Ikawa M
AD  - a Department of Physical Therapy, School of Rehabilitation , Hyogo University of 
      Health Sciences , Kobe , Japan.
FAU - Nakano, Yoshiki
AU  - Nakano Y
AD  - a Department of Physical Therapy, School of Rehabilitation , Hyogo University of 
      Health Sciences , Kobe , Japan.
FAU - Sekiyama, Takashi
AU  - Sekiyama T
AD  - a Department of Physical Therapy, School of Rehabilitation , Hyogo University of 
      Health Sciences , Kobe , Japan.
FAU - Kou, Keihou
AU  - Kou K
AD  - b School of Nursing , Hyogo University of Health Sciences , Kobe , Japan.
FAU - Kashiwamura, Shin-Ichiro
AU  - Kashiwamura SI
AD  - c General Education Center, Hyogo University of Health Sciences , Kobe , Japan.
AD  - d Institute for Advanced Medical Sciences, Hyogo College of Medicine , 
      Nishinomiya , Japan.
FAU - Takeda, Chisako
AU  - Takeda C
AD  - b School of Nursing , Hyogo University of Health Sciences , Kobe , Japan.
FAU - Fujioka, Hiroyuki
AU  - Fujioka H
AD  - a Department of Physical Therapy, School of Rehabilitation , Hyogo University of 
      Health Sciences , Kobe , Japan.
LA  - eng
PT  - Journal Article
DEP - 20180529
PL  - Germany
TA  - Eur J Sport Sci
JT  - European journal of sport science
JID - 101146739
RN  - 0 (Brain-Derived Neurotrophic Factor)
RN  - 7171WSG8A2 (BDNF protein, human)
SB  - IM
MH  - Bicycling/physiology
MH  - Brain/*physiology
MH  - Brain-Derived Neurotrophic Factor/*physiology
MH  - *Cognition
MH  - *Exercise
MH  - Humans
MH  - Learning
MH  - Male
MH  - Memory
MH  - Oxygen Consumption
MH  - Stroop Test
MH  - Young Adult
OTO - NOTNLM
OT  - Exercise
OT  - aerobic exercise
OT  - brain-derived neurotrophic factor
OT  - cognition
OT  - dual-task
EDAT- 2018/05/31 06:00
MHDA- 2018/09/06 06:00
CRDT- 2018/05/30 06:00
PHST- 2018/05/31 06:00 [pubmed]
PHST- 2018/09/06 06:00 [medline]
PHST- 2018/05/30 06:00 [entrez]
AID - 10.1080/17461391.2018.1470676 [doi]
PST - ppublish
SO  - Eur J Sport Sci. 2018 Sep;18(8):1119-1127. doi: 10.1080/17461391.2018.1470676. 
      Epub 2018 May 29.