PMID- 29850454 OWN - NLM STAT- MEDLINE DCOM- 20190211 LR - 20190215 IS - 2291-2797 (Electronic) IS - 2291-2789 (Print) IS - 2291-2789 (Linking) VI - 2018 DP - 2018 TI - Long-Term Management of Recurrent Cholecystitis after Initial Conservative Treatment: Endoscopic Transpapillary Gallbladder Stenting. PG - 3983707 LID - 10.1155/2018/3983707 [doi] LID - 3983707 AB - BACKGROUND: Endoscopic transpapillary gallbladder stenting (ETGBS) is an effective procedure for treating high-risk patients with acute cholecystitis and severe comorbidities. However, the efficacy of ETGBS for recurrent cholecystitis (RC) remains unclear. This study aimed to explore its efficacy in patients with RC for whom cholecystectomy is contraindicated because of its high surgical risk. METHODS: Data on 19 high-risk patients who had undergone ETGBS for RC after initial conservative therapy in our institution between June 2006 and May 2012 were retrospectively examined. The primary outcome was the clinical success rate, which was defined as no recurrences of acute cholecystitis after ETGBS until death or the end of the follow-up period. Secondary outcomes were technical success rate and adverse events (AEs). RESULTS: The clinical success rate of ETGBS was 100%, the technical success rate 94.7%, and AE rate 5%: one patient developed procedure-related mild acute pancreatitis. The clinical courses of all patients were as follows: four died of nonbiliary disease, and the remaining 15 were subsequently treated conservatively. The median duration of follow-up was 14.95 months (range 3-42 months). CONCLUSIONS: ETGBS is an effective alternative for managing RC in high-risk patients with severe comorbidities. FAU - Kamada, Hideki AU - Kamada H AUID- ORCID: 0000-0002-0715-645X AD - Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan. FAU - Kobara, Hideki AU - Kobara H AD - Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan. FAU - Uchida, Naohito AU - Uchida N AD - Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan. FAU - Kato, Kiyohito AU - Kato K AD - Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan. FAU - Fujimori, Takayuki AU - Fujimori T AD - Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan. FAU - Kobayashi, Kiyoyuki AU - Kobayashi K AD - Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan. FAU - Yamashita, Takuma AU - Yamashita T AD - Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan. FAU - Ono, Masahiro AU - Ono M AD - Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan. FAU - Aritomo, Yuichi AU - Aritomo Y AD - Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan. FAU - Tsutsui, Kunihiko AU - Tsutsui K AD - Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan. FAU - Okano, Keiichi AU - Okano K AD - Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan. FAU - Suzuki, Yasuyuki AU - Suzuki Y AD - Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan. FAU - Masaki, Tsutomu AU - Masaki T AD - Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan. LA - eng PT - Journal Article DEP - 20180412 PL - Egypt TA - Can J Gastroenterol Hepatol JT - Canadian journal of gastroenterology & hepatology JID - 101623613 SB - IM MH - Aged MH - Aged, 80 and over MH - Ampulla of Vater MH - Cholangiopancreatography, Endoscopic Retrograde/adverse effects/*methods MH - Cholecystitis, Acute/*therapy MH - Conservative Treatment MH - Female MH - Gallbladder MH - Humans MH - Male MH - Middle Aged MH - Recurrence MH - Retreatment MH - Retrospective Studies MH - *Stents/adverse effects MH - Time Factors PMC - PMC5925167 EDAT- 2018/06/01 06:00 MHDA- 2019/02/12 06:00 PMCR- 2018/04/12 CRDT- 2018/06/01 06:00 PHST- 2017/05/29 00:00 [received] PHST- 2017/12/19 00:00 [revised] PHST- 2018/01/14 00:00 [accepted] PHST- 2018/06/01 06:00 [entrez] PHST- 2018/06/01 06:00 [pubmed] PHST- 2019/02/12 06:00 [medline] PHST- 2018/04/12 00:00 [pmc-release] AID - 10.1155/2018/3983707 [doi] PST - epublish SO - Can J Gastroenterol Hepatol. 2018 Apr 12;2018:3983707. doi: 10.1155/2018/3983707. eCollection 2018.