PMID- 29855460
OWN - NLM
STAT- MEDLINE
DCOM- 20181016
LR  - 20181114
IS  - 1643-3750 (Electronic)
IS  - 1234-1010 (Print)
IS  - 1234-1010 (Linking)
VI  - 24
DP  - 2018 Jun 1
TI  - Predictive Value of Indocyanine Green Plasma Disappearance Rate on Liver Function 
      and Complications After Liver Transplantation.
PG  - 3661-3669
LID - 10.12659/MSM.907783 [doi]
AB  - BACKGROUND The aim of this study was to investigate the correlation between 
      indocyanine green plasma disappearance rate (ICG-PDR) and allograft function as 
      well as postoperative complications after liver transplantation. MATERIAL AND 
      METHODS In this prospective study, 115 cases of adult liver transplantation 
      performed from 1 June 2016 to 1 December 2016 were enrolled. These 115 patients 
      were divided into a group of PDR <18%/min (50 cases) and a group of PDR >/=18%/min 
      (65 cases). The rates of liver recovery, postoperative complications, and 
      survival were compared between these 2 groups. RESULTS Among the total of 115 
      patients, 111 patients recovered well and were discharged, whereas 4 patients 
      died during the first month after the operation. Between the 2 groups, 
      significant differences were observed in terms of the model for end-stage liver 
      disease (MELD) score, intraoperative bleeding volume, and the level of hemoglobin 
      (Hb), pre-albumin (PA) and total bilirubin (TB) the first week after the 
      operation. Overall, the incidence of hepatic arterial complications and pneumonia 
      was much higher in the PDR<18%/min group (P<0.05). CONCLUSIONS The early 
      postoperative value of ICG-PDR was closely related to graft function and could 
      act as a good predictor for the incidence of postoperative arterial 
      complications.
FAU - Sun, Yan
AU  - Sun Y
AD  - Department of Organ Transplantation, Tianjin First Central Hospital, Tianjin, 
      China (mainland).
FAU - Yu, Lixin
AU  - Yu L
AD  - Department of Organ Transplantation, Tianjin First Central Hospital, Tianjin, 
      China (mainland).
FAU - Liu, Yihe
AU  - Liu Y
AD  - Department of Organ Transplantation, Tianjin First Central Hospital, Tianjin, 
      China (mainland).
LA  - eng
PT  - Journal Article
DEP - 20180601
PL  - United States
TA  - Med Sci Monit
JT  - Medical science monitor : international medical journal of experimental and 
      clinical research
JID - 9609063
RN  - 0 (Biomarkers)
RN  - 0 (Indicators and Reagents)
RN  - IX6J1063HV (Indocyanine Green)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Biomarkers
MH  - Female
MH  - Humans
MH  - Indicators and Reagents/metabolism/pharmacokinetics
MH  - Indocyanine Green/metabolism/pharmacokinetics
MH  - Liver/metabolism
MH  - Liver Function Tests/*methods
MH  - Liver Transplantation/adverse effects
MH  - Male
MH  - Middle Aged
MH  - Postoperative Complications/etiology
MH  - Postoperative Period
MH  - Prognosis
MH  - Prospective Studies
MH  - Transplantation Tolerance/*physiology
PMC - PMC6007494
COIS- Conflict of interest None.
EDAT- 2018/06/02 06:00
MHDA- 2018/10/17 06:00
PMCR- 2018/06/01
CRDT- 2018/06/02 06:00
PHST- 2018/06/02 06:00 [entrez]
PHST- 2018/06/02 06:00 [pubmed]
PHST- 2018/10/17 06:00 [medline]
PHST- 2018/06/01 00:00 [pmc-release]
AID - 907783 [pii]
AID - 10.12659/MSM.907783 [doi]
PST - epublish
SO  - Med Sci Monit. 2018 Jun 1;24:3661-3669. doi: 10.12659/MSM.907783.