PMID- 29863096
OWN - NLM
STAT- MEDLINE
DCOM- 20191104
LR  - 20191104
IS  - 1347-4820 (Electronic)
IS  - 1346-9843 (Linking)
VI  - 82
IP  - 8
DP  - 2018 Jul 25
TI  - Prognostic Value of Electrocardiography in Patients With Fulminant Myocarditis 
      Supported by Percutaneous Venoarterial Extracorporeal Membrane Oxygenation　- 
      Analysis From the CHANGE PUMP Study.
PG  - 2089-2095
LID - 10.1253/circj.CJ-18-0136 [doi]
AB  - BACKGROUND: Fulminant myocarditis (FM) presents various abnormal findings on ECG, 
      the prognostic impact of which has not been not fully elucidated. The aim of this 
      study was therefore to clarify the prognostic value of ECG data in FM patients 
      supported by venoarterial extracorporeal membrane oxygenation 
      (VA-ECMO).Methods and Results:In this multicenter chart review, we investigated 
      99 patients with FM supported by VA-ECMO. The final cohort consisted of 87 
      patients (mean age, 52+/-16 years; female, 42%) after 12 patients who required 
      conversion to other forms of mechanical circulatory support were excluded. The 
      median LVEF was 14.5%. At the time of VA-ECMO initiation, 38 patients (44%) had 
      arrhythmias including atrial fibrillation (6%), complete atrioventricular block 
      (CAVB; 17%), and ventricular tachycardia or fibrillation (VT/VF; 15%). Of the 49 
      patients with sinus rhythm (SR), 26 had QRS duration >/=120 ms (wide QRS). On 
      logistic regression analysis, wide QRS predicted in-hospital death in patients 
      with SR (OR, 3.6; 95% CI: 1.07-13.61, P=0.04). Compared with SR with narrow QRS 
      (QRS duration <120 ms), CAVB and VT/VF had a higher risk of in-hospital death 
      (CAVB: OR, 7.20; 95% CI: 1.78-34.15, P=0.005; VT/VF: OR, 8.10; 95% CI: 
      1.86-42.31, P=0.005). CONCLUSIONS: In patients with FM, CAVB and VT/VF carried a 
      higher risk of in-hospital death. Wide QRS also predicted a higher risk of 
      in-hospital death in patients with SR.
FAU - Sawamura, Akinori
AU  - Sawamura A
AD  - Department of Cardiology, Nagoya University Graduate School of Medicine.
FAU - Okumura, Takahiro
AU  - Okumura T
AD  - Department of Cardiology, Nagoya University Graduate School of Medicine.
FAU - Ito, Masaaki
AU  - Ito M
AD  - Department of Cardiology and Nephrology, Mie University Graduate School of 
      Medicine.
FAU - Ozaki, Yukio
AU  - Ozaki Y
AD  - Department of Cardiology, Fujita Health University.
FAU - Ohte, Nobuyuki
AU  - Ohte N
AD  - Department of Cardio-Renal Medicine and Hypertension, Nagoya City University 
      Graduate School of Medical Sciences.
FAU - Amano, Tetsuya
AU  - Amano T
AD  - Department of Cardiology, Aichi Medical University Hospital.
FAU - Murohara, Toyoaki
AU  - Murohara T
AD  - Department of Cardiology, Nagoya University Graduate School of Medicine.
CN  - CHANGE PUMP Investigators
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20180601
PL  - Japan
TA  - Circ J
JT  - Circulation journal : official journal of the Japanese Circulation Society
JID - 101137683
SB  - IM
MH  - Adult
MH  - Aged
MH  - Arrhythmias, Cardiac/*mortality
MH  - Atrial Fibrillation/mortality
MH  - Atrioventricular Block/mortality
MH  - Electrocardiography/*methods
MH  - Extracorporeal Membrane Oxygenation/*methods
MH  - Female
MH  - Hospital Mortality
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocarditis/*diagnosis/therapy
MH  - Prognosis
MH  - Tachycardia, Ventricular/mortality
OTO - NOTNLM
OT  - Electrocardiogram
OT  - Extracorporeal circulation
OT  - Myocarditis
OT  - Prognosis
EDAT- 2018/06/05 06:00
MHDA- 2019/11/05 06:00
CRDT- 2018/06/05 06:00
PHST- 2018/06/05 06:00 [pubmed]
PHST- 2019/11/05 06:00 [medline]
PHST- 2018/06/05 06:00 [entrez]
AID - 10.1253/circj.CJ-18-0136 [doi]
PST - ppublish
SO  - Circ J. 2018 Jul 25;82(8):2089-2095. doi: 10.1253/circj.CJ-18-0136. Epub 2018 Jun 
      1.