PMID- 29865159
OWN - NLM
STAT- MEDLINE
DCOM- 20190118
LR  - 20230926
IS  - 1660-4601 (Electronic)
IS  - 1661-7827 (Print)
IS  - 1660-4601 (Linking)
VI  - 15
IP  - 6
DP  - 2018 Jun 1
TI  - Which Compounds Contribute Most to Elevated Soil Pollution and the Corresponding 
      Health Risks in Floodplains in the Headwater Areas of the Central European 
      Watershed?
LID - 10.3390/ijerph15061146 [doi]
LID - 1146
AB  - The main topic of this study is a human health risk assessment of a defined 
      exposure scenario in the floodplain soils of the headwater areas of the central 
      European watershed, with the aim of exploring both multivariate and regional data 
      structures. Flood-prone areas are recognized worldwide to be susceptible to 
      contamination and its redistribution. Contributions of various classes of toxic 
      compounds (organochlorine pesticides (OCPs), polycyclic aromatic hydrocarbons 
      (PAHs), polychlorinated biphenyls (PCBs)) to human health risks were assessed in 
      a screening risk assessment. However, due to the relative nature of our data and 
      a high PAH dominancy over the data ensemble, reliance solely on the standard 
      statistical processing of raw data might lead to incomplete insight into the 
      structure of the multivariate data. Explanatory analysis of the data structure 
      using the compositional approach was found to be beneficial to elucidating human 
      health risk profiles and provided robust evidence that a contrast between 
      agricultural and airborne industrial pollution controlled the whole human 
      toxicological variation of persistent organic pollutants (POPs) in floodplain 
      soils. These results were effectively quantified with the subcomposition of 
      benzo(a)pyrene, DDT, and alpha-hexachlorocyclohexane (aHCH), allowing for an 
      interpretation of structural differences in regional pollution patterns, which 
      conferred different extents and compositions of human health risks in floodplain 
      soils.
FAU - Skala, Jan
AU  - Skala J
AD  - Research Institute for Soil and Water Conservation, Zabovreska 250, 15627 Prague, 
      Czech Republic. skala.jan@vumop.cz.
FAU - Vacha, Radim
AU  - Vacha R
AD  - Research Institute for Soil and Water Conservation, Zabovreska 250, 15627 Prague, 
      Czech Republic. vacha.radim@vumop.cz.
FAU - Cupr, Pavel
AU  - Cupr P
AD  - Research Centre for Toxic Compounds in the Environment, Masaryk University, 
      Kamenice 753-5, 62500 Brno, Czech Republic. cupr@recetox.muni.cz.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20180601
PL  - Switzerland
TA  - Int J Environ Res Public Health
JT  - International journal of environmental research and public health
JID - 101238455
RN  - 0 (Environmental Pollutants)
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 0 (Pesticides)
RN  - 0 (Polycyclic Aromatic Hydrocarbons)
RN  - 0 (Soil)
RN  - 0 (Soil Pollutants)
RN  - 319-84-6 (alpha-hexachlorocyclohexane)
RN  - 59NEE7PCAB (Hexachlorocyclohexane)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
SB  - IM
MH  - Algorithms
MH  - *Environmental Monitoring
MH  - Environmental Pollutants/*analysis
MH  - Europe
MH  - *Floods
MH  - Hexachlorocyclohexane/analysis
MH  - Humans
MH  - Hydrocarbons, Chlorinated/analysis
MH  - Pesticides/analysis
MH  - Polychlorinated Biphenyls/analysis
MH  - Polycyclic Aromatic Hydrocarbons/analysis
MH  - Soil/*chemistry
MH  - Soil Pollutants/*analysis
PMC - PMC6025328
OTO - NOTNLM
OT  - compositional data
OT  - floodplain
OT  - human health risk
OT  - soil pollution
COIS- The authors declare that they have no conflicts of interest.
EDAT- 2018/06/06 06:00
MHDA- 2019/01/19 06:00
PMCR- 2018/06/01
CRDT- 2018/06/06 06:00
PHST- 2018/04/13 00:00 [received]
PHST- 2018/05/25 00:00 [revised]
PHST- 2018/05/29 00:00 [accepted]
PHST- 2018/06/06 06:00 [entrez]
PHST- 2018/06/06 06:00 [pubmed]
PHST- 2019/01/19 06:00 [medline]
PHST- 2018/06/01 00:00 [pmc-release]
AID - ijerph15061146 [pii]
AID - ijerph-15-01146 [pii]
AID - 10.3390/ijerph15061146 [doi]
PST - epublish
SO  - Int J Environ Res Public Health. 2018 Jun 1;15(6):1146. doi: 
      10.3390/ijerph15061146.