PMID- 29865198 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20201001 IS - 2079-4991 (Print) IS - 2079-4991 (Electronic) IS - 2079-4991 (Linking) VI - 8 IP - 6 DP - 2018 Jun 1 TI - Investigating the Synthesis and Characterization of a Novel "Green" H(2)O(2)-Assisted, Water-Soluble Chitosan/Polyvinyl Alcohol Nanofiber for Environmental End Uses. LID - 10.3390/nano8060395 [doi] LID - 395 AB - The present work highlights the formation of a novel green nanofiber based on H(2)O(2)-assisted water-soluble chitosan/polyvinyl alcohol (W(S)CHT/PVA) by using water as an ecofriendly solvent and genipin used as a nontoxic cross-linker. The 20/80 blend ratio was found to have the most optimum uniform fiber morphology. W(S)CHT retained the same structure as W(IS)CHT. The prepared nanofibers were characterized by Scanning electron microscopy (SEM), Fourier transform spectroscopy (FTIR), Thermo gravimetric analysis (TGA), Differential scanning calorimeter (DSC), X-ray diffraction (XRD), Water Contact Angle (WCA) and Ultraviolet-visible spectroscopy (UV-vis). During electrospinning, the crystalline microstructure of the W(S)CHT/PVA underwent better solidification and after cross-linking there was an increase in the melting temperature of the fiber. Swelling ratio studies revealed noticeable increase in hydrophilicity with increase of W(S)CHT, which was further demonstrated by the decrease of contact angle from 64.74 degrees to 14.68 degrees . W(S)CHT/PVA nanofiber mats exhibit excellent UV blocking protection with less than 5% transmittance value and also showed improved in vitro drug release properties with stable release for longer duration (cross-linked fibers) and burst release for shorter duration (uncross linked) fibers. Finally our experimental data demonstrates excellent adsorption ability of Colour Index (C.I.) reactive black 5 (RB5) due to protonated amino groups. FAU - Pervez, Md Nahid AU - Pervez MN AUID- ORCID: 0000-0001-6187-5351 AD - Research Institute for Flexible Materials, School of Textiles and Design, Heriot-Watt University, Galashiels TD1 3HF, UK. nahid.tex92@gmail.com. FAU - Stylios, George K AU - Stylios GK AD - Research Institute for Flexible Materials, School of Textiles and Design, Heriot-Watt University, Galashiels TD1 3HF, UK. g.stylios@hw.ac.uk. LA - eng PT - Journal Article DEP - 20180601 PL - Switzerland TA - Nanomaterials (Basel) JT - Nanomaterials (Basel, Switzerland) JID - 101610216 PMC - PMC6027504 OTO - NOTNLM OT - Hesperetin OT - Reactive black 5 OT - ecofriendly solvent OT - green nanofiber OT - water soluble chitosan COIS- The authors declare no conflicts of interest. EDAT- 2018/06/06 06:00 MHDA- 2018/06/06 06:01 PMCR- 2018/06/01 CRDT- 2018/06/06 06:00 PHST- 2018/05/08 00:00 [received] PHST- 2018/05/30 00:00 [revised] PHST- 2018/05/31 00:00 [accepted] PHST- 2018/06/06 06:00 [entrez] PHST- 2018/06/06 06:00 [pubmed] PHST- 2018/06/06 06:01 [medline] PHST- 2018/06/01 00:00 [pmc-release] AID - nano8060395 [pii] AID - nanomaterials-08-00395 [pii] AID - 10.3390/nano8060395 [doi] PST - epublish SO - Nanomaterials (Basel). 2018 Jun 1;8(6):395. doi: 10.3390/nano8060395.