PMID- 29871253
OWN - NLM
STAT- MEDLINE
DCOM- 20180830
LR  - 20181202
IS  - 2096-7993 (Print)
IS  - 2096-7993 (Linking)
VI  - 31
IP  - 4
DP  - 2017 Feb 20
TI  - [Research advancement in related genes of Meniere's disease].
PG  - 318-323
LID - 10.13201/j.issn.1001-1781.2017.04.019 [doi]
AB  - Starting from rational bases for a genetic approach to Meniere's disease (MD), we 
      explored the numerous reports published in literature and summarized the recent 
      advances in understanding of the genetic fundaments of the disease. The research 
      advances related to the genetic fundaments of MD were reviewed. The incidence of 
      MD presents as familial clustering and hasdifference in geographical and racial, 
      no certain gene associated with MD was found. At present, studies concentrate on 
      those genes, such as human leukocyte antigen (HLA), DFNA9, chromosome 12, 
      macrophage migration inhibitory factor(MIF), KCNE, and heat shock protein (HSP). 
      However, there have much arguments in diagnose, classify and pathophysiology of 
      MD, resulting in different conclusion and prospect. The characteristics of MD 
      strongly suggest a certain role for genetic factors in the development of MD, no 
      convincing evidence for an association with any gene exists. To make a more 
      strict quality control and continue explore the genetic factors of MD, will be 
      meaningful in the future.
CI  - Copyright(c) by the Editorial Department of Journal of Clinical Otorhinolaryngology 
      Head and Neck Surgery.
FAU - Li, Y J
AU  - Li YJ
FAU - Jin, Z G
AU  - Jin ZG
FAU - Xu, X R
AU  - Xu XR
LA  - chi
PT  - Journal Article
PT  - Review
PL  - China
TA  - Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
JT  - Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical 
      otorhinolaryngology, head, and neck surgery
JID - 101303164
SB  - IM
MH  - Genetic Predisposition to Disease/*genetics
MH  - Humans
MH  - Meniere Disease/*genetics
OTO - NOTNLM
OT  - Meniere disease
OT  - genes
OT  - vertigo
COIS- The authors of this article and the planning committee members and staff have no 
      relevant financial relationships with commercial interests to disclose.
EDAT- 2017/02/20 00:00
MHDA- 2018/08/31 06:00
CRDT- 2018/06/06 06:00
PHST- 2016/10/12 00:00 [received]
PHST- 2018/06/06 06:00 [entrez]
PHST- 2017/02/20 00:00 [pubmed]
PHST- 2018/08/31 06:00 [medline]
AID - 10.13201/j.issn.1001-1781.2017.04.019 [doi]
PST - ppublish
SO  - Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2017 Feb 20;31(4):318-323. doi: 
      10.13201/j.issn.1001-1781.2017.04.019.