PMID- 29880553
OWN - NLM
STAT- MEDLINE
DCOM- 20190826
LR  - 20220318
IS  - 1524-4628 (Electronic)
IS  - 0039-2499 (Linking)
VI  - 49
IP  - 7
DP  - 2018 Jul
TI  - Nonconvulsive Status Epilepticus in Acute Intracerebral Hemorrhage.
PG  - 1759-1761
LID - 10.1161/STROKEAHA.118.021414 [doi]
AB  - BACKGROUND AND PURPOSE: Patients with acute intracerebral hemorrhages (ICHs) 
      often develop nonconvulsive status epilepticus (NCSE). We aimed to identify 
      determinants and the prognostic significance of NCSE among patients with acute 
      ICH. METHODS: Consecutive patients with acute spontaneous ICH who were admitted 
      to a comprehensive stroke center were enrolled. We diagnosed NCSE using the 
      modified Salzburg Consensus Criteria. Factors associated with NCSE and their 
      significance in relation to clinical outcomes were assessed using multivariate 
      logistic regression models. RESULTS: Of 228 patients (136 men; mean age, 68+/-14 
      years), 20 (8.8%) developed NCSE during their hospital stays. In logistic 
      regression models, the adjusted odds ratios (95% confidence intervals) for NCSE 
      were 3.5 (1.2-10.7) for craniotomy and 7.0 (2.2-31.2) for lobar involvement. The 
      patients with NCSE had higher modified Rankin Scale scores at discharge, but NCSE 
      was not independently associated with poor functional outcomes (modified Rankin 
      Scale score, 4-5) or mortality after adjusting for confounders. CONCLUSIONS: NCSE 
      is not a rare complication of acute ICH. Craniotomy and lobar involvement are 
      independently associated with NCSE in patients with acute ICH.
CI  - (c) 2018 American Heart Association, Inc.
FAU - Matsubara, Soichiro
AU  - Matsubara S
AD  - From the Stroke and Epilepsy Center, TMG Asaka Medical Center, Asaka, Saitama, 
      Japan (S.M., T.K., S.E., H.N., Y.K.) matsubara-soichiro@umin.ac.jp.
AD  - Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular 
      Center, Suita, Osaka, Japan (S.M., S.S., K.T).
FAU - Sato, Shoichiro
AU  - Sato S
AD  - Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular 
      Center, Suita, Osaka, Japan (S.M., S.S., K.T).
FAU - Kodama, Tomohiro
AU  - Kodama T
AD  - From the Stroke and Epilepsy Center, TMG Asaka Medical Center, Asaka, Saitama, 
      Japan (S.M., T.K., S.E., H.N., Y.K.).
FAU - Egawa, Satoshi
AU  - Egawa S
AD  - From the Stroke and Epilepsy Center, TMG Asaka Medical Center, Asaka, Saitama, 
      Japan (S.M., T.K., S.E., H.N., Y.K.).
FAU - Nakamoto, Hidetoshi
AU  - Nakamoto H
AD  - From the Stroke and Epilepsy Center, TMG Asaka Medical Center, Asaka, Saitama, 
      Japan (S.M., T.K., S.E., H.N., Y.K.).
FAU - Toyoda, Kazunori
AU  - Toyoda K
AD  - Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular 
      Center, Suita, Osaka, Japan (S.M., S.S., K.T).
FAU - Kubota, Yuichi
AU  - Kubota Y
AD  - From the Stroke and Epilepsy Center, TMG Asaka Medical Center, Asaka, Saitama, 
      Japan (S.M., T.K., S.E., H.N., Y.K.).
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20180607
PL  - United States
TA  - Stroke
JT  - Stroke
JID - 0235266
MH  - Aged
MH  - Aged, 80 and over
MH  - Cerebral Hemorrhage/*complications
MH  - Electroencephalography
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prognosis
MH  - Risk Factors
MH  - Status Epilepticus/*etiology
MH  - Stroke/*complications
OTO - NOTNLM
OT  - cerebral hemorrhage
OT  - electroencephalography
OT  - humans
OT  - patient discharge
OT  - seizure
EDAT- 2018/06/09 06:00
MHDA- 2019/08/27 06:00
CRDT- 2018/06/09 06:00
PHST- 2018/01/10 00:00 [received]
PHST- 2018/05/08 00:00 [revised]
PHST- 2018/05/15 00:00 [accepted]
PHST- 2018/06/09 06:00 [pubmed]
PHST- 2019/08/27 06:00 [medline]
PHST- 2018/06/09 06:00 [entrez]
AID - STROKEAHA.118.021414 [pii]
AID - 10.1161/STROKEAHA.118.021414 [doi]
PST - ppublish
SO  - Stroke. 2018 Jul;49(7):1759-1761. doi: 10.1161/STROKEAHA.118.021414. Epub 2018 
      Jun 7.