PMID- 29881275 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220317 IS - 1176-6328 (Print) IS - 1178-2021 (Electronic) IS - 1176-6328 (Linking) VI - 14 DP - 2018 TI - Musical dual-task training in patients with mild-to-moderate dementia: a randomized controlled trial. PG - 1381-1393 LID - 10.2147/NDT.S159174 [doi] AB - BACKGROUND/AIMS: Dual-task training may improve dual-task gait performance, balance, and cognition in older adults with and without cognitive impairment. Although music has been widely utilized in dementia management, there are no existing protocols for music-based dual-task training. This randomized controlled study developed a Musical Dual-Task Training (MDTT) protocol that patients with dementia can use to practice walking and making music simultaneously, to enhance attention control in patients during dual-tasking. METHODS: Twenty-eight adults diagnosed with mild-to-moderate dementia were assigned to the MDTT (n=15) or control groups (n=13). The MDTT group received MDTT, while the control group participated in non-musical cognitive and walking activities. The effects of MDTT were evaluated through the primary outcome of attention control, and secondary outcomes of dual-task performance, balance, falls efficacy, and agitation. RESULTS: The MDTT group showed a significant improvement in attention control, while the control group did not (P<0.001). A significant effect favored MDTT over control treatment for the secondary outcome of falls efficacy (P=0.02) and agitation (P<0.01). CONCLUSION: MDTT, a music therapy intervention that demands a high level of cognitive processing, enhances attention control, falls efficacy, and helps alleviate agitation in patients with mild-to-moderate dementia. FAU - Chen, Yu-Ling AU - Chen YL AD - Department of Music, Southwestern Oklahoma State University, Weatherford, OK, USA. AD - Division of Music Education and Music Therapy, University of Kansas, Lawrence, KS, USA. FAU - Pei, Yu-Cheng AU - Pei YC AD - Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Taoyuan, Taiwan. AD - Center of Vascularized Tissue Allograft, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan. AD - School of Medicine, Chang Gung University, Taoyuan, Taiwan. AD - Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan. LA - eng PT - Journal Article DEP - 20180530 PL - New Zealand TA - Neuropsychiatr Dis Treat JT - Neuropsychiatric disease and treatment JID - 101240304 PMC - PMC5985768 OTO - NOTNLM OT - agitation OT - attention OT - dementia OT - incidental falls OT - music therapy COIS- Disclosure The authors report no conflicts of interest in this work. EDAT- 2018/06/09 06:00 MHDA- 2018/06/09 06:01 PMCR- 2018/05/30 CRDT- 2018/06/09 06:00 PHST- 2018/06/09 06:00 [entrez] PHST- 2018/06/09 06:00 [pubmed] PHST- 2018/06/09 06:01 [medline] PHST- 2018/05/30 00:00 [pmc-release] AID - ndt-14-1381 [pii] AID - 10.2147/NDT.S159174 [doi] PST - epublish SO - Neuropsychiatr Dis Treat. 2018 May 30;14:1381-1393. doi: 10.2147/NDT.S159174. eCollection 2018.