PMID- 29885827
OWN - NLM
STAT- MEDLINE
DCOM- 20190311
LR  - 20190311
IS  - 1874-1754 (Electronic)
IS  - 0167-5273 (Linking)
VI  - 271
DP  - 2018 Nov 15
TI  - Prognostic value of myocardial deformation imaging by cardiac magnetic resonance 
      feature-tracking in patients with a first ST-segment elevation myocardial 
      infarction.
PG  - 387-391
LID - S0167-5273(18)31109-4 [pii]
LID - 10.1016/j.ijcard.2018.05.082 [doi]
AB  - AIM: Scarce data are available whether cardiac magnetic resonance (CMR) 
      assessment of myocardial deformation provides independent and incremental 
      prognostic information in patients with ST-segment elevation myocardial 
      infarction (STEMI). The aim of the present study was to investigate the 
      prognostic utility of CMR feature-tracking derived left ventricular (LV) global 
      circumferential strain (GCS) in STEMI patients. METHODS: A total of 180 patients 
      (mean age 60 +/- 12 years, 72% male) admitted because of a first STEMI were 
      included. CMR with late gadolinium enhancement (LGE) imaging was performed to 
      assess LV function, infarct size, and microvascular obstruction. The 
      feature-tracking analysis was applied to cine-CMR short-axis images to assess LV 
      GCS. Patients were followed-up for a median of 95 months. The outcome event was a 
      composite endpoint including cardiovascular death, aborted sudden cardiac death, 
      and hospitalization for heart failure. RESULTS: During follow-up, 40 (22%) 
      patients experienced at least 1 event. After adjustment for other clinical and 
      CMR imaging characteristics, LV GCS remained significantly and independently 
      associated with the outcome event (HR 1.16 per %; 95% CI 1.07-1.25; p < 0.001). A 
      significant increase of global chi(2) was observed when adding LV GCS to a model 
      including clinical and non-contrast CMR variables (chi(2) change = 8.2; p = 0.004) 
      and to a model including clinical, non-contrast and LGE variables (chi(2) 
      change = 4.8; p = 0.028). CONCLUSION: LV GCS assessed by CMR feature-tracking can 
      predict a worse long-term prognosis in patients admitted with a first STEMI. More 
      importantly, the predictive ability of LV GCS is incremental to other clinical 
      and CMR variables.
CI  - Copyright (c) 2018 Elsevier B.V. All rights reserved.
FAU - Nucifora, Gaetano
AU  - Nucifora G
AD  - Department of Heart Health, South Australian Health & Medical Research Institute, 
      Adelaide, Australia; School of Medicine, Flinders University, Bedford Park, 
      Adelaide, Australia; Northwest Heart Centre, Wythenshawe Hospital, Manchester 
      University NHS Foundation Trust, Manchester, UK. Electronic address: 
      gaetano.nucifora@flinders.edu.au.
FAU - Muser, Daniele
AU  - Muser D
AD  - Cardiothoracic Department, Azienda Sanitaria Universitaria Integrata, Udine, 
      Italy.
FAU - Tioni, Chiara
AU  - Tioni C
AD  - Cardiothoracic Department, Azienda Sanitaria Universitaria Integrata, Udine, 
      Italy; Postgraduate School of Cardiovascular Sciences, University of Trieste, 
      Trieste, Italy.
FAU - Shah, Ranjit
AU  - Shah R
AD  - Department of Heart Health, South Australian Health & Medical Research Institute, 
      Adelaide, Australia; School of Medicine, Flinders University, Bedford Park, 
      Adelaide, Australia; Department of Cardiovascular Medicine, Flinders Medical 
      Centre, Bedford Park, Adelaide, Australia.
FAU - Selvanayagam, Joseph B
AU  - Selvanayagam JB
AD  - Department of Heart Health, South Australian Health & Medical Research Institute, 
      Adelaide, Australia; School of Medicine, Flinders University, Bedford Park, 
      Adelaide, Australia; Department of Cardiovascular Medicine, Flinders Medical 
      Centre, Bedford Park, Adelaide, Australia.
LA  - eng
PT  - Journal Article
DEP - 20180526
PL  - Netherlands
TA  - Int J Cardiol
JT  - International journal of cardiology
JID - 8200291
SB  - IM
MH  - Aged
MH  - Female
MH  - Follow-Up Studies
MH  - Heart/*diagnostic imaging/physiopathology
MH  - Humans
MH  - Magnetic Resonance Imaging, Cine/*methods/trends
MH  - Male
MH  - Middle Aged
MH  - Patient Admission/trends
MH  - Prognosis
MH  - ST Elevation Myocardial Infarction/*diagnostic imaging/mortality/physiopathology
OTO - NOTNLM
OT  - Cardiac magnetic resonance
OT  - Feature-tracking
OT  - Global circumferential strain
OT  - Prognosis
OT  - ST-elevation myocardial infarction
EDAT- 2018/06/11 06:00
MHDA- 2019/03/12 06:00
CRDT- 2018/06/11 06:00
PHST- 2018/02/17 00:00 [received]
PHST- 2018/04/26 00:00 [revised]
PHST- 2018/05/22 00:00 [accepted]
PHST- 2018/06/11 06:00 [pubmed]
PHST- 2019/03/12 06:00 [medline]
PHST- 2018/06/11 06:00 [entrez]
AID - S0167-5273(18)31109-4 [pii]
AID - 10.1016/j.ijcard.2018.05.082 [doi]
PST - ppublish
SO  - Int J Cardiol. 2018 Nov 15;271:387-391. doi: 10.1016/j.ijcard.2018.05.082. Epub 
      2018 May 26.