PMID- 29886622
OWN - NLM
STAT- MEDLINE
DCOM- 20190207
LR  - 20201013
IS  - 1001-0939 (Print)
IS  - 1001-0939 (Linking)
VI  - 41
IP  - 6
DP  - 2018 Jun 12
TI  - [Diagnostic value of endobronchial ultrasonography with guide-sheath combined 
      with virtual bronchoscopy navigation in peripheral lung cancer].
PG  - 472-476
LID - 10.3760/cma.j.issn.1001-0939.2018.06.008 [doi]
AB  - Objective: To explore the diagnostic value and safety of endobronchial 
      ultrasonography with guide-sheath (EBUS-GS) combined with virtual bronchoscopy 
      navigation (VBN) in peripheral lung cancer. Methods: Between Dec. 2015 to Dec. 
      2016, patients with pulmonary solitary nodule suspected of early lung cancer on 
      computed tomography (CT) in Department of Respiratory, Tangdu Hospital, Fourth 
      Military Medical University were enrolled for this study. The patients underwent 
      EBUS-GS transbronchoscopic lung biopsy (TBLB) with or without VBN. The visibility 
      rate, diagnostic yield, influencing factors, the operation time and complications 
      were evaluated in the 2 groups. The data were compared using independent sample t 
      test or chi-squared test. Results: A total of 134 patients were enrolled and 
      completed this study. Among them 74 were males and 60 were females. There were 64 
      cases in the group of EBUS-GS with VBN (VBNA), and 70 in the group without VBN 
      (NVBNA). The visibility rate and diagnosis rate of VBNA group were 87.5% (56/64) 
      and 78.1% (50/64), respectively. The mean time of operation and confirming the 
      target lesions were (25+/-5), (5.8+/-1.3) min, respectively. The visibility rate and 
      diagnosis rate of NVBNA group were 81.4%(57/70) and 75.7%(53/70), respectively. 
      The mean time of operation and confirming the target lesions were (27+/-6), 
      (9.8+/-1.5)min .There was no significant difference in the visibility rate and 
      diagnosis rate between the 2 groups (chi(2)=0.933, P=0.334; chi(2)=0.109, P=0.838). 
      There was no significant difference in the mean operation time between the 2 
      groups(t=0.633, P=0.524). But the time of confirming the target lesions between 
      the 2 groups was statistically different (t=17.41, P<0.01). EBUS-GS-TBLB was well 
      tolerated. No severe complications such as pneumothorax or chest pain were 
      observed. There were 3 patients in the VBNA group and 7 patients in the NVBNA 
      group experiencing a small amount of biopsy site bleeding. The incidence of 
      complications did not differ between the 2 groups(chi(2)=1.366, P=0.330). 
      Conclusions: VBN could not improve the diagnostic yield of EBUS-GS. However, it 
      could shorten the time needed to confirm the target lesions and did not increase 
      the incidence of EBUS-GS complications, indicating that EBUS-GS with VBN was a 
      safe and effective method.
FAU - Fang, F
AU  - Fang F
AD  - Department of Respiratory Medicine, Tangdu Hospital, Fourth Military Medical 
      University, Xi'an 710038, China.
FAU - Pan, L
AU  - Pan L
FAU - Bo, L Y
AU  - Bo LY
FAU - Li, W P
AU  - Li WP
FAU - Fu, E Q
AU  - Fu EQ
FAU - Li, C C
AU  - Li CC
FAU - Jin, F G
AU  - Jin FG
LA  - chi
PT  - Journal Article
PL  - China
TA  - Zhonghua Jie He He Hu Xi Za Zhi
JT  - Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal 
      of tuberculosis and respiratory diseases
JID - 8712226
SB  - IM
MH  - Biopsy/*methods
MH  - Bronchoscopy/*methods
MH  - Endosonography
MH  - Female
MH  - Humans
MH  - Lung/*diagnostic imaging/pathology
MH  - Lung Neoplasms/diagnostic imaging/*pathology
MH  - Male
MH  - Tomography, X-Ray Computed
MH  - Ultrasonography/*methods
OTO - NOTNLM
OT  - Bronchoscopy
OT  - Diagnosis, computer-assisted
OT  - Lung neoplasms
OT  - Ultrasonography
EDAT- 2018/06/12 06:00
MHDA- 2019/02/08 06:00
CRDT- 2018/06/11 06:00
PHST- 2018/06/11 06:00 [entrez]
PHST- 2018/06/12 06:00 [pubmed]
PHST- 2019/02/08 06:00 [medline]
AID - 10.3760/cma.j.issn.1001-0939.2018.06.008 [doi]
PST - ppublish
SO  - Zhonghua Jie He He Hu Xi Za Zhi. 2018 Jun 12;41(6):472-476. doi: 
      10.3760/cma.j.issn.1001-0939.2018.06.008.