PMID- 29888237
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240318
IS  - 2297-4725 (Print)
IS  - 2297-475X (Electronic)
IS  - 2297-4725 (Linking)
VI  - 34
IP  - 2
DP  - 2018 Apr
TI  - Diagnostic Investigations of Gastroesophageal Reflux Disease: Who and When to 
      Refer and for What Test?
PG  - 97-100
LID - 10.1159/000488184 [doi]
AB  - BACKGROUND: Due to the high prevalence and incidence of patients with 
      gastroesophageal reflux disease (GERD), the diagnostic workup of patients with 
      symptoms of GERD needs to be balanced between empiric antisecretory therapy and 
      further functional assessment including endoscopy and reflux monitoring. METHODS: 
      This article is based on a literature review (PubMed, Medline) using the terms 
      'gastroesophageal reflux disease' or 'GERD' and 'diagnosis', 'therapy', or 'PPI' 
      with special and critical analysis of the current 'Porto' consensus report. 
      RESULTS AND CONCLUSIONS: Further diagnostics are mandatory in case of alarm 
      symptoms as well as atypical or persistent symptoms under adequate therapy with 
      proton pump inhibitors (PPI). In general, the clinical situation needs to be 
      clarified before sending the patients for reflux monitoring. The question is not 
      only when and whom to test but also how to test: on or off PPI therapy, pH-metry, 
      or combined pH-impedance analysis. These questions have been defined in a recent 
      consensus report of an international panel of experts and are further discussed 
      in this article.
FAU - Kandulski, Arne
AU  - Kandulski A
AD  - Department of Internal Medicine I, University Hospital Regensburg, Regensburg, 
      Germany.
FAU - Moleda, Lukas
AU  - Moleda L
AD  - Department of Internal Medicine I, University Hospital Regensburg, Regensburg, 
      Germany.
FAU - Muller-Schilling, Martina
AU  - Muller-Schilling M
AD  - Department of Internal Medicine I, University Hospital Regensburg, Regensburg, 
      Germany.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20180420
PL  - Switzerland
TA  - Visc Med
JT  - Visceral medicine
JID - 101681546
PMC - PMC5981635
OTO - NOTNLM
OT  - Diagnostics
OT  - Gastroesophageal reflux disease
OT  - Proton pump inhibitors
OT  - Therapy
OT  - pH-metry
EDAT- 2018/06/12 06:00
MHDA- 2018/06/12 06:01
PMCR- 2019/04/01
CRDT- 2018/06/12 06:00
PHST- 2018/06/12 06:00 [entrez]
PHST- 2018/06/12 06:00 [pubmed]
PHST- 2018/06/12 06:01 [medline]
PHST- 2019/04/01 00:00 [pmc-release]
AID - vis-0034-0097 [pii]
AID - 10.1159/000488184 [doi]
PST - ppublish
SO  - Visc Med. 2018 Apr;34(2):97-100. doi: 10.1159/000488184. Epub 2018 Apr 20.